Surprise: Mobile Devices Don't Help Office Ergonomics
Surprise: Mobile devices don't help office ergonomics
"For decades, ergonomics was billed as a way to get people to stay at their desks longer and more productively," notes Dr. James Levine, director of obesity solutions at the Mayo Clinic, in… Continue reading
Susceptibility Genes Are Enriched in Those of the HSV-1/host Interactome in Psychiatric and Neurological Disorders.
Susceptibility genes are enriched in those of the HSV-1/host interactome in psychiatric and neurological disorders.
Pathog Dis. 2013 Aug 3;
Carter CJ
Herpes simplex (HSV-1) can promote beta-amyloid deposition and tau phosphorylation, demyelination or cognitive deficits relevant to Alzheimer’s disease or multiple sclerosis and to many neuropsychiatric disorders with which it has been implicated. A seroprevalence much higher than disease incidence has called into question any primary causal role. However, as also the case with risk promoting polymorphisms, (also present in control populations) any causal effects are likely to be conditional. During its life cycle, the virus binds to many proteins and modifies the expression of multiple genes creating a host/pathogen interactome involving 1347 host genes. This dataset is heavily enriched in the susceptibility genes for multiple sclerosis (P= 1.3E-99) >Alzheimer’s disease > schizophrenia > Parkinsonism > depression> bipolar disorder> childhood obesity> chronic fatigue> autism > and anorexia (P=0.047) but not ADHD, a relationship maintained for GWAS datasets in multiple sclerosis and Alzheimer’s… Continue reading
Outcomes Research Study Reveals Strong Effectiveness of Wilderness-Based …
Outcomes Research Study Reveals Strong Effectiveness of Wilderness-Based …
The prospective, IRB (Institutional Review Board) approved, multi-site clinical study sampled young adults from three treatment sites: two wilderness-based treatment programs and one treatment-as-usual inpatient program. The study assessed participants …… Continue reading
[Functional and Aesthetic Rehabilitation of Microtia in Children and Adolescents].
[Functional and aesthetic rehabilitation of microtia in children and adolescents].
HNO. 2013 Aug; 61(8): 655-61
Hempel JM, Braun T, Berghaus A
Microtia leads to a severe functional and aesthetic handicap. Traditionally, the auricle is often reconstructed with cartilage transplants,… Continue reading
Addictive Behaviors Related to Opioid Use for Chronic Pain: A Population-Based Study.
Addictive behaviors related to opioid use for chronic pain: A population-based study.
Pain. 2013 Jul 29;
Højsted J, Ekholm O, Kurita GP, Juel K, Sjøgren P
The growing body of research showing increased opioid use in patients with chronic… Continue reading
Epidemiology of Drug Use Among Biracial/ethnic Youth and Young Adults: Results From a U.S. Population-Based Survey.
Epidemiology of drug use among biracial/ethnic youth and young adults: results from a U.S. population-based survey.
J Psychoactive Drugs. 2013 Apr-Jun; 45(2): 99-111
Clark TT, Nguyen AB, Kropko J
This study estimates the prevalence of cigarette, alcohol, and marijuana… Continue reading
Tentative Evidence for Striatal Hyperactivity in Adolescent Cannabis-Using Boys: A Cross-Sectional Multicenter fMRI Study.
Tentative evidence for striatal hyperactivity in adolescent cannabis-using boys: a cross-sectional multicenter fMRI study.
J Psychoactive Drugs. 2013 Apr-Jun; 45(2): 156-67
Jager G, Block RI, Luijten M, Ramsey NF
Adolescents’ risk-taking behavior has been linked to a maturational imbalance… Continue reading
Mechanisms of Resistance to Sorafenib and the Corresponding Strategies in Hepatocellular Carcinoma.
Mechanisms of resistance to sorafenib and the corresponding strategies in hepatocellular carcinoma.
World J Hepatol. 2013 Jul 27; 5(7): 345-52
Zhai B, Sun XY
Sorafenib, the unique drug as first-line treatment for advanced hepatocellular carcinoma (HCC), has opened a… Continue reading