Rehab Centers Network

Statin a day keeps cancer at bay.

World J Clin Oncol. 2013 May 10; 4(2): 43-6
Singh S, Singh PP

In addition to cholesterol reduction, statins, currently the most commonly prescribed drug in the world, have been shown to have anti-neoplastic and immunomodulatory effects. Several observational studies and meta-analyses have shown reduction in risk of multiple cancers. More recently there has been an increasing interest in the potential role of statins as adjuvant therapy after cancer diagnosis and in modifying cancer mortality. Although post-hoc analyses of randomized controlled trials of statins for cardiovascular outcomes have not shown reduction in the risk of cancer mortality with statin use, these studies lack sufficient power to detect a significant difference in cancer outcomes. Recently, in a Danish nationwide population-based cohort study, Nielsen et al showed a 15% reduction in all-cause and cancer-specific mortality in statin users as compared to non-users. Improved survival with statin exposure was seen in 13/27 cancer subtypes, including the 4 most common cancers – lung, prostate, colorectal and breast. In this commentary, we examine this important study, review its implications and limitations, and briefly discuss impact of other drugs like metformin and aspirin that also exhibit anti-neoplastic effects. HubMed – drug

Chronic Unpredictable Stress (CUS)-Induced Anxiety and Related Mood Disorders in a Zebrafish Model: Altered Brain Proteome Profile Implicates Mitochondrial Dysfunction.

PLoS One. 2013; 8(5): e63302
Chakravarty S, Reddy BR, Sudhakar SR, Saxena S, Das T, Meghah V, Brahmendra Swamy CV, Kumar A, Idris MM

Anxiety and depression are major chronic mood disorders, and the etiopathology for each appears to be repeated exposure to diverse unpredictable stress factors. Most of the studies on anxiety and related mood disorders are performed in rodents, and a good model is chronic unpredictable stress (CUS). In this study, we have attempted to understand the molecular basis of the neuroglial and behavioral changes underlying CUS-induced mood disorders in the simplest vertebrate model, the zebrafish, Danio rerio. Zebrafish were subjected to a CUS paradigm in which two different stressors were used daily for 15 days, and thorough behavioral analyses were performed to assess anxiety and related mood disorder phenotypes using the novel tank test, shoal cohesion and scototaxis. Fifteen days of exposure to chronic stressors appears to induce an anxiety and related mood disorder phenotype. Decreased neurogenesis, another hallmark of anxiety and related disorders in rodents, was also observed in this zebrafish model. The common molecular markers of rodent anxiety and related disorders, corticotropin-releasing factor (CRF), calcineurin (ppp3r1a) and phospho cyclic AMP response element binding protein (pCREB), were also replicated in the fish model. Finally, using 2DE FTMS/ITMSMS proteomics analyses, 18 proteins were found to be deregulated in zebrafish anxiety and related disorders. The most affected process was mitochondrial function, 4 of the 18 differentially regulated proteins were mitochondrial proteins: PHB2, SLC25A5, VDAC3 and IDH2, as reported in rodent and clinical samples. Thus, the zebrafish CUS model and proteomics can facilitate not only uncovering new molecular targets of anxiety and related mood disorders but also the routine screening of compounds for drug development. HubMed – depression

McGill EDP: Eating Disorders on Campus – For more information, check out our website http://www.mcgill.ca/mentalhealth/edp or search for us on Facebook.

Alternative approach to treating mental illness offered at Bloomfield practice
The center treats an array of mental illnesses including Schizophrenia, bipolar, obsessive compulsive, eating disorders, depression, anxiety, insomnia, TIC disorder, ADD and autism spectrum disorder. Advance Biomedical Treatment Center has great … Read more on Foothills Media Group

Charge Rolf Harris or clear him
Given that it was billed as "the perfect treat for all the family", it certainly doesn't appear that he's viewed by police as any sort of ongoing safety risk. It's fair to say, however, … She claims she developed an eating disorder and even attempted … Read more on Herald Sun

Taste and Smell Disorders Are Devastating and Surprisingly Common
Eating is essential for our survival, and enjoyment of food and drink ensures this process is maintained. These senses also serve as a hazard warning system to help us avoid dangers such as gas leaks and spoiled … CP: The ear dominates the ear, nose … Read more on Slate Magazine

Rehabilitation Center – A proposed Rehabilitation Centre in India near Allahabad, UP to treat alcohol and drug addicts. http://www.missionoftherisenchrist.org/rehab.html.

F.A.S.T. response to stroke symptoms
Risk factors for stroke include untreated high blood pressure, abnormal heartbeat, smoking, excessive alcohol use, high cholesterol, uncontrolled diabetes, excess weight, lack of regular exercise and untreated circulation problems. Daly said the … Read more on The Union of Grass Valley

An observational study of nutrition and physical activity behaviors, knowledge, and advice in pregnancy.

BMC Pregnancy Childbirth. 2013 May 20; 13(1): 115
de Jersey SJ, Nicholson JM, Callaway LK, Daniels LA

BACKGROUND: Maternal obesity, excess weight gain and lifestyle behaviours during pregnancy have been associated with future overweight and other adverse health outcomes for mothers and babies. This study compared the nutrition and physical activity behaviours of Australian healthy (BMI <= 25k/m2) and overweight (BMI >= 25kg/m2) pregnant women and described their knowledge and receipt of health professional advice early in pregnancy. METHODS: Pregnant women (n=58) aged 29+/-5 (mean+/-s.d.) years were recruited at 16+/-2 weeks gestation from an Australian metropolitan hospital.. Height and weight were measured using standard procedures and women completed a self administered semi-quantitative survey. RESULTS: Healthy and overweight women had very similar levels of knowledge, behaviour and levels of advice provided except where specifically mentioned. Only 8% and 36% of participants knew the correct recommended daily number of fruit and vegetable serves respectively. Four percent of participants ate the recommended 5 serves/day of vegetables. Overweight women were less likely than healthy weight women to achieve the recommended fruit intake (4% vs. 8%, p=0.05), and more likely to consume soft drinks or cordial (55% vs 43%, p=0.005) and take away foods (37% vs. 25%, p=0.002) once a week or more. Less than half of all women achieved sufficient physical activity. Despite 80% of women saying they would have liked education about nutrition, physical activity and weight gain, particularly at the beginning of pregnancy, less than 50% were given appropriate advice regarding healthy eating and physical activity. CONCLUSION: Healthy pregnancy behaviour recommendations were not being met, with overweight women less likely to meet some of the recommendations. Knowledge of dietary recommendations was poor and health care professional advice was limited. There are opportunities to improve the health care practices and education pregnant women received to improve knowledge and behaviours. Pregnant women appear to want this. HubMed – eating

Type of mask may impact on continuous positive airway pressure adherence in apneic patients.

PLoS One. 2013; 8(5): e64382
Borel JC, Tamisier R, Dias-Domingos S, Sapene M, Martin F, Stach B, Grillet Y, Muir JF, Levy P, Series F, Pepin JL,

In obstructive sleep apnea patients (OSA), continuous positive airway pressure (CPAP) adherence is crucial to improve symptoms and cardiometabolic outcomes. The choice of mask may influence CPAP adherence but this issue has never been addressed properly.To evaluate the impact of nasal pillows, nasal and oronasal masks on CPAP adherence in a cohort of OSA.Newly CPAP treated OSA participating in “Observatoire Sommeil de la Fédération de Pneumologie”, a French national prospective cohort, were included between March 2009 and December 2011. Anthropometric data, medical history, OSA severity, sleepiness, depressive status, treatment modalities (auto-CPAP versus fixed pressure, pressure level, interface type, use of humidifiers) and CPAP-related side effects were included in multivariate analysis to determine independent variables associated with CPAP adherence.2311 OSA (age?=?57(12) years, apnea+hypopnea index?=?41(21)/h, 29% female) were included. Nasal masks, oronasal masks and nasal pillows were used by 62.4, 26.2 and 11.4% of the patients, respectively. In univariate analysis, oronasal masks and nasal pillows were associated with higher risk of CPAP non-adherence. CPAP non-adherence was also associated with younger age, female gender, mild OSA, gastroesophageal reflux, depression status, low effective pressure and CPAP-related side effects. In multivariate analysis, CPAP non-adherence was associated with the use of oronasal masks (OR?=?2.0; 95%CI?=?1.6; 2.5), depression, low effective pressure, and side effects.As oronasal masks negatively impact on CPAP adherence, a nasal mask should be preferred as the first option. Patients on oronasal masks should be carefully followed. HubMed – depression

Wendy Adams & Kevin Tyson- www.danceforselfesteem.org – 2nd Annual Celebrity Dance Challenge, Thursday Oct. 21st @ 7pm, 14th Street Playhouse, Atlanta GA Fashioned after hit shows like So You Think You Can Dance T…

Calm urged in wake of dog theft reports
Review for man's faked injury compo · Broken arm. A MEDICAL panel found a man incapable of working because he suffered from a disorder that made him feign injury. … Face-eating victim plays guitar in video · Face-chewing victim Ronald Poppo on the … Read more on Herald Sun

'Forget diets, get an eating disorder': Shocking pro-anorexia websites urging …
This comes after hospital admissions for eating disorders in England rose by 16% between June 2011 and June 2012 according to the Health and Social Care Information Centre (HSCIC). Pro-anorexia websites condemn curvy women for their crimes against … Read more on Mancunian Matters

Rabbitte cool on plea to censor eating disorder websites
“The parents of children affected by these eating disorders have told me they have found evidence of these sites being accessed by their children,” said the Kerry North-West Limerick TD. “It is a similar problem with suicide in that there is just too … Read more on Irish Examiner

Are All Herbs Toxic #488 –

Is Ginger Really Better Than Drugs for Pain?
While betamethasone has been used for decades to relieve pain, it is also linked with many serious side-effects, including: vision problems, weight gain, swelling, shortness of breath, depression, seizures, pancreatitis, heart arrhythmias, muscle … Read more on Ecorazzi

A national treasure with heart-rending songs
The compelling Demons confronts self-doubt and depression as Berninger sings, with brutal honesty: "When I walk into a room, I do not light it up." Slipped captures this …. UK Eurovision remedy? Little Boots reckons she could be the UK's Eurovision … Read more on Irish Independent

EXCLUSIVE: Jared Evan – The New Prince Of Hip-Hop Blues
JaredEvan. View Comments. Share with Shortlink: A direct line can be drawn between Blues and Hip-Hop. Legendary blues artists like Muddy Waters, Robert Johnson, John Lee Hooker, and B.B.King helped lay the foundation of using music as a cathartic … Read more on AllHipHop

Permanent mechanical deformation of an intrathecal baclofen pump secondary to scuba diving: a case report.

Spinal Cord. 2013 May 21;
Draulans N, Roels E, Kiekens C, Nuttin B, Peers K

Study design:Case report.Objectives:To describe the case of a spinal cord injury patient that went scuba diving resulting in a mechanical deformation of his intrathecal baclofen pump.Setting:University Hospitals Leuven, Belgium.Methods:Case report.Results:Diving below 10 meters of depth can result in irreversible mechanical damage of the drug reservoir of an intrathecal baclofen pump.Conclusion:Patients with an intrathecal baclofen pump should be warned for the risks associated with scuba diving and should not dive more than 10 meters below sea level.Spinal Cord advance online publication, 21 May 2013; doi:10.1038/sc.2013.43. HubMed – rehab

Neglected traumatic spinal cord injuries: experience sharing from Pakistan.

Spinal Cord. 2013 May 21;
Rathore FA

HubMed – rehab

Examining factors that contribute to the process of resilience following spinal cord injury.

[Laryngeal mask anesthesia in video-assisted thoracoscopic surgery for pulmonary bulla: comparison with intubation anesthesia].

Nan Fang Yi Ke Da Xue Xue Bao. 2013 May; 33(5): 756-60
Cai KC, Wang XD, Ye J, Diao DW, He JX, Liu J, Huang ZY, Wu H

OBJEVTIVE: ToTo assess the feasibility and safety of thoracoscopic bulla resection under laryngeal mask anesthesia with low tidal volume high-frequency lung ventilation.Sixty patients with pulmonary bulla were randomized into two groups (n=30) to undergo video-assisted thoracoscopic surgery (VATS) for bulla resection with laryngeal mask anesthesia and high-frequency low tidal volume lung ventilation general anesthesia and or with intubation anesthesia and one-lung ventilation through double-lumen endotracheal intubation.No significant differences were found in anesthesia time, surgery time, intraoperative lowest SpO2, intraoperative highest PetCO2, operative field, anesthetic effects, or blood loss between the two groups. The post-operative WBC and NEU% showed significantly smaller increments in the mask anesthesia group than in the intubation group, and the postoperative awake time, initial eating time, ambulation time, in-hospital stay, and drainage time were significantly shortened in the former group with also lower incidences of gastrointestinal reactions, throat discomfort and hoarseness.Thoracoscopic bulla resection under laryngeal mask anesthesia with low tidal volume high-frequency lung ventilation is safe and feasible and results in better patient satisfaction and shorter in-hospital stay than procedures performed under intubation anesthesia with one-lung ventilation. HubMed – eating