Drug discovery

Anyone Know of Good & Effective Dual Diagnosis Rehab Centers?

Published April 25, 2014

Question by Anthony B: Anyone know of good & effective dual diagnosis rehab centers?
I’ve decided to get myself some help and need advice on treatment centers. I need a place that specializes in mental-illness(more specifically, bipolar) along… Continue reading →

Ketamine Can Treat Severe Depression

Published April 9, 2014

Ketamine Can Treat Severe Depression
(Source: The first UK study of the use of ketamine intravenous infusions in people with treatment-resistant depression has been carried out in an NHS clinic by researchers at Oxford Health NHS Foundation Trust and the… Continue reading →

Savino “Sonny” J. D'Angelico

Published October 13, 2013

Savino “Sonny” J. D'Angelico
In lieu of flowers, memorial donations can be made in Sonny's name to St. Jude's Children's Research Center, 501 St. Jude's Place, Memphis, TN, 38105; to St. Joseph's Church, 164 Broadway, Fort Edward, NY 12828; or… Continue reading →

Why Are Most Chemo Drugs Synthetic Rather Than Biogenic?

Published September 28, 2013

Question by yug_zohoth: Why are most chemo drugs synthetic rather than biogenic?
I’m curious to know why cancer chemotherapy still relies on the usage and further “drug discovery” of synthetic drugs which are injected into the bloodstream and thus affect… Continue reading →

OLANZAPINE ACTIVATES HEPATIC MAMMALIAN TARGET of RAPAMYCIN (MTOR): NEW MECHANISTIC INSIGHT INTO METABOLIC DYSREGULATION WITH ATYPICAL ANTIPSYCHOTIC DRUGS.

Published August 10, 2013

OLANZAPINE ACTIVATES HEPATIC MAMMALIAN TARGET OF RAPAMYCIN (mTOR): NEW MECHANISTIC INSIGHT INTO METABOLIC DYSREGULATION WITH ATYPICAL ANTIPSYCHOTIC DRUGS.

J Pharmacol Exp Ther. 2013 Aug 7;
Schmidt RH, Jokinen JD, Massey VL, Falkner KC, Shi X, Yin X, Zhang X,… Continue reading →

Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids.

Published August 6, 2013

Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids.

Chem Sci. 2013 Apr 1; 4(4): 1646-1657
Boyer N, Morrison KC, Kim J, Hergenrother PJ, Movassaghi M

The epipolythiodiketopiperazine (ETP) alkaloids are a highly complex class of natural products with potent anticancer… Continue reading →

Adherence to Treatment With Imatinib in Chronic Myeloid Leukemia: A Study of the First Decade of Responses Obtained at a Brazilian Hospital.

Published August 3, 2013

Adherence to treatment with imatinib in chronic myeloid leukemia: a study of the first decade of responses obtained at a Brazilian hospital.

Rev Bras Hematol Hemoter. 2013; 35(3): 174-9
Dos Reis SR, Quixadá AT, Nunes ST, Cid DM, de… Continue reading →

Drug Dependence: Cancer Medicine.

Published July 17, 2013

Drug dependence: Cancer medicine.

Contemp Clin Dent. 2013 Jan; 4(1): 1
Damle SG

HubMed – drug

State of the globe: antimicrobial stewardship guides rationale use of antimicrobials to enable faster cure and prevent drug resistance.

J Glob Infect Dis… Continue reading →

Mutation in Ribosomal Protein S5 Leads to Spectinomycin Resistance in Neisseria Gonorrhoeae.

Published July 14, 2013

Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae.

Front Microbiol. 2013; 4: 186
Ilina EN, Malakhova MV, Bodoev IN, Oparina NY, Filimonova AV, Govorun VM

Spectinomycin remains a useful reserve option for therapy of gonorrhea.… Continue reading →

Combined Radio- and Chemotherapy for Non-Small Cell Lung Cancer: Systematic Review of Landmark Studies Based on Acquired Citations.

Published July 13, 2013

Combined Radio- and Chemotherapy for Non-Small Cell Lung Cancer: Systematic Review of Landmark Studies Based on Acquired Citations.

Front Oncol. 2013; 3: 176
Nieder C, Pawinski A, Andratschke NH

The important role of combined chemoradiation for several groups of… Continue reading →