Clinical trial

Correlation of Angiogenic Biomarker Signatures With Clinical Outcomes in Metastatic Colorectal Cancer Patients Receiving Capecitabine, Oxaliplatin, and Bevacizumab.

Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab.

Cancer Med. 2013 Apr; 2(2): 234-42
Liu Y, Starr MD, Bulusu A, Pang H, Wong NS, Honeycutt W, Amara A, Hurwitz… Continue reading

Multidrug-Resistance and Extended Spectrum Beta-Lactamase Production in Uropathogenic E. Coli Which Were Isolated From Hospitalized Patients in Kolkata, India.

Multidrug-Resistance and Extended Spectrum Beta-Lactamase Production in Uropathogenic E. Coli which were Isolated from Hospitalized Patients in Kolkata, India.

J Clin Diagn Res. 2013 Mar; 7(3): 449-53
Mukherjee M, Basu S, Mukherjee SK, Majumder M

Background and Objective: Urinary… Continue reading

Vagal Nerve Stimulator: Evolving Trends.

Vagal nerve stimulator: Evolving trends.

J Nat Sci Biol Med. 2013 Jan; 4(1): 8-13
Ogbonnaya S, Kaliaperumal C

Over three decades ago, it was found that intermittent electrical stimulation from the vagus nerve produces inhibition of neural processes, which… Continue reading

Find Novel Dual-Agonist Drugs for Treating Type 2 Diabetes by Means of Cheminformatics.

Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics.

Drug Des Devel Ther. 2013; 7: 279-88
Liu L, Ma Y, Wang RL, Xu WR, Wang SQ, Chou KC

The high prevalence of type 2 diabetes… Continue reading

Update on the Treatment of Non-Small-Cell Lung Cancer: Focus on the Cost-Effectiveness of New Agents.

Update on the treatment of non-small-cell lung cancer: focus on the cost-effectiveness of new agents.

Clinicoecon Outcomes Res. 2013; 5: 137-41
Vergnenègre A, Borget I, Chouaid C

The incidence of lung cancer and the cost of drug treatment have… Continue reading

Can MDMA Play a Role in the Treatment of Substance Abuse?

Can MDMA Play a Role in the Treatment of Substance Abuse?

Curr Drug Abuse Rev. 2013 Apr 29;
Jerome L, Shira Schuster MA, Yazar-Klosinski BB

A wider array of treatments are needed for people with substance abuse disorders. Some… Continue reading

Human Experimental Pain Models: A Review of Standardized Methods in Drug Development.

Human experimental pain models: A review of standardized methods in drug development.

J Res Med Sci. 2012 Jun; 17(6): 587-95
Reddy KS, Naidu MU, Rani PU, Rao TR

Human experimental pain models are essential in understanding the pain mechanisms… Continue reading

THE SERTRALINE VERSUS ELECTRICAL CURRENT THERAPY for TREATING DEPRESSION CLINICAL STUDY (SELECT-TDCS): RESULTS of the CROSSOVER and FOLLOW-UP PHASES.

THE SERTRALINE VERSUS ELECTRICAL CURRENT THERAPY FOR TREATING DEPRESSION CLINICAL STUDY (SELECT-TDCS): RESULTS OF THE CROSSOVER AND FOLLOW-UP PHASES.

Depress Anxiety. 2013 Apr 26;
Valiengo L, Benseñor IM, Goulart AC, de Oliveira JF, Zanao TA, Boggio PS, Lotufo PA,… Continue reading

Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions.

Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions.

PLoS One. 2013; 8(4): e62576
D’Agnillo F, Williams MC, Moayeri M, Warfel JM

Vascular leakage pathologies such as pleural effusion and hemorrhage are hallmarks of anthrax pathogenesis. We… Continue reading

Chlamydophila Pneumoniae Infection and Cardiovascular Disease.

Chlamydophila pneumoniae infection and cardiovascular disease.

N Am J Med Sci. 2013 Mar; 5(3): 169-81
Joshi R, Khandelwal B, Joshi D, Gupta OP

Atherosclerosis is a multifactorial vascular inflammatory process; however, the inciting cause for inflammation remains unclear. Two… Continue reading