tumor cells

Cellular Switch Controls Growth of Brain Tumor Cells

Cellular switch controls growth of brain tumor cells
Researchers believe that the protein, found in most glioblastomas, can be targeted to develop a drug treatment for these highly malignant brain tumors. The study was published online Aug. … “Our study… Continue reading

Molecular Distribution of Amino Acid Substitutions on Neuraminidase From the 2009 (H1N1) Human Influenza Pandemic Virus.

Molecular distribution of amino acid substitutions on neuraminidase from the 2009 (H1N1) human influenza pandemic virus.

Bioinformation. 2013; 9(13): 673-9
Quiliano M, Valdivia-Olarte H, Olivares C, Requena D, Gutiérrez AH, Reyes-Loyola P, Tolentino-Lopez LE, Sheen P, Briz V, Muñoz-Fernández… Continue reading

Randomized Trials Built on Sand: Examples From COPD, Hormone Therapy, and Cancer.

Randomized Trials Built on Sand: Examples from COPD, Hormone Therapy, and Cancer.

Rambam Maimonides Med J. 2012 Jul; 3(3): e0014
Suissa S

The randomized controlled trial is the fundamental study design to evaluate the effectiveness of medications and receive… Continue reading

Strategies to Increase Drug Penetration in Solid Tumors.

Strategies to increase drug penetration in solid tumors.

Front Oncol. 2013; 3: 193
Choi IK, Strauss R, Richter M, Yun CO, Lieber A

Despite significant improvement in modalities for treatment of cancer that led to a longer survival period,… Continue reading

Antiproliferative Activity of New Benzimidazole Derivatives.

Antiproliferative activity of new benzimidazole derivatives.

Acta Biochim Pol. 2013 Jul 25;
B?aszczak-?wi?tkiewicz K, Olszewska P, Mikiciuk-Olasik E

A series of new benzimidazole derivatives were synthesized and tested in vitro for possible anticancer activity. Their effect of proliferation into… Continue reading

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

PLoS One. 2013; 8(6): e68016
Gründemann C, Thell K, Lengen K, Garcia-Käufer M, Huang YH, Huber R, Craik DJ, Schabbauer G, Gruber CW

Cyclotides are a diverse and abundant… Continue reading

Autophagy in Breast Cancer and Its Implications for Therapy.

Autophagy in breast cancer and its implications for therapy.

Am J Cancer Res. 2013; 3(3): 251-65
Jain K, Paranandi KS, Sridharan S, Basu A

Autophagy is an evolutionarily conserved process of cellular self-digestion that serves as a mechanism to… Continue reading

Critical Appraisal of Ranibizumab in the Treatment of Diabetic Macular Edema.

Critical appraisal of ranibizumab in the treatment of diabetic macular edema.

Clin Ophthalmol. 2013; 7: 1257-67
Stewart MW

Diabetic retinopathy is the leading cause of blindness among individuals of working age in industrialized nations, with most of the vision… Continue reading

Identification of (2-Aminopropyl)indole Positional Isomers in Forensic Samples.

Identification of (2-aminopropyl)indole positional isomers in forensic samples.

Drug Test Anal. 2013 Jul 8;
Scott KR, Power JD, McDermott SD, O’Brien JE, Talbot BN, Barry MG, Kavanagh PV

In 2012, 5-(2-aminopropyl)indole (5-API, 5-IT) was reported by Norwegian authorities to… Continue reading

Exceptions to and Deviations From the INN Common Stem System.

Exceptions to and deviations from the INN common stem system.

Prescrire Int. 2013 May; 22(138): 138-9

For various reasons, mainly related to the history of the drug and of drug nomenclature, some INNs lack a common stem. As INN… Continue reading