United States — the Threat of Malpractice. How Much Does It Contribute…?
Question by titou: United States — The threat of malpractice. How much does it contribute…?
…to MDs “herding” into prescribing the same diagnosis, treatment and particularly medication?
I am thinking particularly of psychiatry, but perhaps this phenomenon happens in… Continue reading
Nucleus Accumbens Surgery for Addiction.
Nucleus Accumbens Surgery for Addiction.
Filed under: Addiction Rehab
World Neurosurg. 2012 Oct 6;
Li N, Wang J, Wang XL, Chang CW, Ge SN, Gao L, Wu HM, Zhao HK, Geng N, Gao GD
Opiate addiction remains intractable in… Continue reading
Rehabilitation for Ataxia Following Chemotherapy for Burkitt Lymphoma Involving the Rectum.
Rehabilitation for ataxia following chemotherapy for burkitt lymphoma involving the rectum.
Filed under: Rehab Centers
Ann Rehabil Med. 2012 Aug; 36(4): 578-83
Kim HS, Jung CO, Jeon HR, Sung LH
Burkitt lymphoma is a type of B-cell lymphoma that… Continue reading
Depression “cures”? Whats Your Preference? Medication or Other..?
Question by o: Depression “cures”? Whats your preference? Medication or other..?
So depression runs in my family…..I mean like serious manic-depression.
Unfortunately……all of my family members have gone with the “quick fix” of a hearty combination of… Continue reading
New Depression Treatment: New Depression Treatments – Old Versus New Depression Treatments
New Depression treatments replace some of the old ones so there can be no discussion of new depression treatments without at least a brief mention of old treatments. Let’s look at some of the old treatments first as it might… Continue reading
Addiction Rehab: [Addictive Internet Use as a Comorbid Disorder Among Clients of an Adolescent Psychiatry – Prevalence and Psychopathological Symptoms].
[Addictive internet use as a comorbid disorder among clients of an adolescent psychiatry – prevalence and psychopathological symptoms].
Filed under: Addiction Rehab
Z Kinder Jugendpsychiatr Psychother. 2012 Sep; 40(5): 331-9
Müller KW, Ammerschläger M, Freisleder FJ, Beutel ME, Wölfling… Continue reading
Role of Reactive Oxygen Species in the Synergistic Cytotoxicity of Safingol-Based Combination Regimens With Conventional Chemotherapeutics.
Role of reactive oxygen species in the synergistic cytotoxicity of safingol-based combination regimens with conventional chemotherapeutics.
Filed under: Drug and Alcohol Rehabilitation
Oncol Lett. 2011 Sep 1; 2(5): 905-910
Ling LU, Tan KB, Chiu GN
Exploiting the sensitivity of cancer cells to reactive oxygen species (ROS) has been suggested as a strategy for the selective elimination of cancer cells. In this study, the ROS-generating sphingolipid safingol was combined with various conventional chemotherapeutics, and the potential synergism of the safingol-based combination regimen was assessed using a panel of cancer cell lines. The IC(50) values of safingol using as a single agent were 1.4-6.3 µM, which are concentrations that are clinically achievable. While synergism was dependent on the drug molar ratios, a 4:1 molar ratio of safingol to conventional chemotherapeutics exhibited a moderate to strong synergism in MDA-MB-231, JIMT-1, SKOV-3, U937 and KB cells, with combination indices ranging from 0.07 to 0.77. Furthermore, the addition of safingol may reduce the concentrations of conventional chemotherapeutics required to achieve 90% cell-kill by 1 to >3 log-folds. A significant… Continue reading