Molecular mechanisms

Transcriptome Sequencing of Gene Expression in the Brain of the HIV-1 Transgenic Rat.

Transcriptome Sequencing of Gene Expression in the Brain of the HIV-1 Transgenic Rat.

PLoS One. 2013; 8(3): e59582
Li MD, Cao J, Wang S, Wang J, Sarkar S, Vigorito M, Ma JZ, Chang SL

The noninfectious HIV-1 transgenic (HIV-1Tg)… Continue reading

Peptide Aptamers: Tools to Negatively or Positively Modulate HSPB1(27) Function.

Peptide aptamers: tools to negatively or positively modulate HSPB1(27) function.

Philos Trans R Soc Lond B Biol Sci. 2013; 368(1617): 20120075
Gibert B, Simon S, Dimitrova V, Diaz-Latoud C, Arrigo AP

Human HSP27 (HSPB1) is a molecular chaperone sensor… Continue reading

Molecular Mechanisms of Cannabinoid Addiction.

Molecular mechanisms of cannabinoid addiction.

Curr Opin Neurobiol. 2013 Mar 12;
Fratta W, Fattore L

Cannabis is the world’s most widely used illicit substance, with an estimated number of 119-224 million users worldwide. In recent years we assisted to… Continue reading

Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations.

Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations.

J Young Pharm. 2012 10; 4(4): 199-200
Manikandan S

HubMed – drug

 

The Role of Phenethyl Isothiocyanate on Bladder Cancer ADM Resistance Reversal and Its Molecular Mechanism.

Anat Rec (Hoboken)… Continue reading

How ‘person-centered’ Care Helped Guide Me Toward Recovery From Mental Illness.

How ‘person-centered’ care helped guide me toward recovery from mental illness.

Health Aff (Millwood). 2013 Mar; 32(3): 622-6
Clayton AR

A community psychiatry researcher reflects on the treatment she received in her youth for post-traumatic stress disorder and depression-and… Continue reading

The Μ Opioid Receptor and Ligands Acting at the Μ Opioid Receptor, as Therapeutics and Potential Therapeutics.

The µ Opioid Receptor and Ligands Acting at the µ Opioid Receptor, as Therapeutics and Potential Therapeutics.

Curr Pharm Des. 2013 Feb 20;
Spetea M, Asim MF, Wolber G, Schmidhammer H

Although the µ opioid receptor (MOR) was pharmacologically… Continue reading

Gene-Environment Interactions in Major Depressive Disorder.

Gene-environment interactions in major depressive disorder.

Can J Psychiatry. 2013 Feb; 58(2): 76-83
Klengel T, Binder EB

Family, twin, and epidemiologic studies have suggested that both genes and environment are important risk factors for the development of major depressive… Continue reading

Transcriptional Mechanisms of Drug Addiction.

Transcriptional mechanisms of drug addiction.

Clin Psychopharmacol Neurosci. 2012 Dec; 10(3): 136-43
Nestler EJ

Regulation of gene expression is considered a plausible mechanism of drug addiction given the stability of behavioral abnormalities that define an addicted state. Numerous transcription… Continue reading

Addiction Rehab: Addiction: A Drug-Induced Disorder of Memory Reconsolidation.

Addiction: a drug-induced disorder of memory reconsolidation.

Filed under: Addiction Rehab

Curr Opin Neurobiol. 2013 Feb 14;
Tronson NC, Taylor JR

Persistent maladaptive memories that maintain drug seeking and are resistant to extinction are a hallmark of addiction. As… Continue reading

Drug and Alcohol Rehabilitation: Virus Host Protein Interaction Network Analysis Reveals That the HEV ORF3 Protein May Interrupt the Blood Coagulation Process.

Virus Host Protein Interaction Network Analysis Reveals That the HEV ORF3 Protein May Interrupt the Blood Coagulation Process.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(2): e56320
Geng Y, Yang J, Huang W, Harrison TJ, Zhou Y,… Continue reading