How ‘person-centered’ Care Helped Guide Me Toward Recovery From Mental Illness.

How ‘person-centered’ care helped guide me toward recovery from mental illness.

Health Aff (Millwood). 2013 Mar; 32(3): 622-6
Clayton AR

A community psychiatry researcher reflects on the treatment she received in her youth for post-traumatic stress disorder and depression-and calls for more recovery-oriented care to be available nationwide. HubMed – depression


Molecular Neurobiology of Depression: PET Findings on the Elusive Correlation with Symptom Severity.

Front Psychiatry. 2013; 4: 8
Smith DF, Jakobsen S

Molecular mechanisms in the brain are assumed to cause the symptoms and severity of neuropsychiatric disorders. This review concerns the elusive nature of relationships between the severity of depressive disorders and neuromolecular processes studied by positron emission tomography (PET). Recent PET studies of human depression have focused on serotonergic, dopaminergic, muscarinic, nicotinic, and GABAergic receptors, as well as central processes dependent on monoamine oxidase, phosphodiesterase type 4, amyloid plaques, neurofibrillar tangles, and P-glycoprotein. We find that reliable causal links between neuromolecular mechanisms and relief from depressive disorders have yet to be convincingly demonstrated. This situation may contribute to the currently limited use of PET for exploring the neuropathways that are currently viewed as being responsible for beneficial effects of antidepressant treatment regimes. HubMed – depression