Hepatitis C

Recombinant Human Butyrylcholinesterase as a New-Age Bioscavenger Drug: Development of the Expression System.

Published April 5, 2013

Recombinant human butyrylcholinesterase as a new-age bioscavenger drug: development of the expression system.

Acta Naturae. 2013 Jan; 5(1): 73-84
Ilyushin DG, Haertley OM, Bobik TV, Shamborant OG, Surina EA, Knorre VD, Masson P, Smirnov IV, Gabibov AG, Ponomarenko NA… Continue reading →

Workplace Bullying – What’s It Got to Do With General Practice?

Published April 4, 2013

Workplace bullying – What’s it got to do with general practice?

Aust Fam Physician. 2013 Apr; 42(4): 186-8
Askew DA, Schluter PJ, Dick ML

Workplace bullying is repeated systematic, interpersonal abusive behaviours that negatively affect the targeted individual and… Continue reading →

[Video Game and Internet Addiction : The Current State of Research.]

Published April 4, 2013

[Video game and internet addiction : The current state of research.]

Nervenarzt. 2013 Apr 4;
Rehbein F, Mößle T, Arnaud N, Rumpf HJ

The use of interactive screen media is widespread and for some users leads to pathological symptoms… Continue reading →

5-Fluorouracil Potentiates the Anti-Cancer Effect of Oxaliplatin on Colo320 Colorectal Adenocarcinoma Cells.

Published March 30, 2013

5-Fluorouracil potentiates the anti-cancer effect of oxaliplatin on Colo320 colorectal adenocarcinoma cells.

J Gastrointestin Liver Dis. 2013 Mar; 22(1): 37-43
Berindan-Neagoe I, Braicu C, Pileczki V, Cojocneanu Petric R, Miron N, Balacescu O, Iancu D, Ciuleanu T

BACKGROUND &… Continue reading →

RASopathic Skin Eruptions During Vemurafenib Therapy.

Published March 23, 2013

RASopathic Skin Eruptions during Vemurafenib Therapy.

PLoS One. 2013; 8(3): e58721
Rinderknecht JD, Goldinger SM, Rozati S, Kamarashev J, Kerl K, French LE, Dummer R, Belloni B

Vemurafenib is a potent inhibitor of V600 mutant BRAF with significant impact… Continue reading →

Analysis of Novel Melphalan Hydrolysis Products Formed Under Isolated Lung Perfusion Conditions Using Liquid Chromatography/tandem Mass Spectrometry.

Published March 16, 2013

Analysis of novel melphalan hydrolysis products formed under isolated lung perfusion conditions using liquid chromatography/tandem mass spectrometry.

Rapid Commun Mass Spectrom. 2013 Apr 15; 27(7): 835-841
Boschmans J, de Bruijn E, Van Schil P, Lemière F

RATIONALE: Melphalan is a widely used cytotoxic agent in cancer treatments. This phenylalanine analog has been shown an effective drug in the treatment of breast cancer, multiple myeloma and melanoma of the extremities. A good knowledge of the drug’s degradation and metabolism are crucial for understanding its activity during cancer treatments. METHODS: The formation of hydrolysis products of melphalan is studied using ultra-performance liquid chromatography (UPLC) tandem mass spectrometry (MS/MS). Aqueous melphalan solutions were incubated at elevated temperatures and analyzed by UPLC/MS/MS. Two previously described hydrolysis products, mono- and dihydroxymelphalan (MOH and DOH), were formed in vitro and could be characterized during MS/MS and high-resolution experiments. RESULTS: Novel compounds with m/z values >500?Da were discovered.… Continue reading →

“We Lost All We Had in a Second”: Coping With Grief and Loss After a Natural Disaster.

Published March 9, 2013

“We lost all we had in a second”: coping with grief and loss after a natural disaster.

World Psychiatry. 2013 Feb; 12(1): 69-75
Ekanayake S, Prince M, Sumathipala A, Siribaddana S, Morgan C

Natural disasters cause immense suffering among… Continue reading →

Cytochrome P450 2E1 Gene Polymorphisms/Haplotypes and Anti-Tuberculosis Drug-Induced Hepatitis in a Chinese Cohort.

Published March 6, 2013

Cytochrome P450 2E1 Gene Polymorphisms/Haplotypes and Anti-Tuberculosis Drug-Induced Hepatitis in a Chinese Cohort.

PLoS One. 2013; 8(2): e57526
Tang S, Lv X, Zhang Y, Wu S, Yang Z, Xia Y, Tu D, Deng P, Ma Y, Chen D, Zhan… Continue reading →

Functional and Structural Neural Network Characterization of Serotonin Transporter Knockout Rats.

Published March 2, 2013

Functional and structural neural network characterization of serotonin transporter knockout rats.

PLoS One. 2013; 8(2): e57780
van der Marel K, Homberg JR, Otte WM, Dijkhuizen RM

Brain serotonin homeostasis is crucially maintained by the serotonin transporter (5-HTT), and its… Continue reading →

The Combined Propranolol/TSST Paradigm – a New Method for Psychoneuroendocrinology.

Published March 2, 2013

The Combined Propranolol/TSST Paradigm – A New Method for Psychoneuroendocrinology.

PLoS One. 2013; 8(2): e57567
Andrews J, Pruessner JC

Upon perception of a stimulus as stressful, the human brain reacts with the activation of the hypothalamus-pituitary-adrenal (HPA) axis and… Continue reading →

Recombinant Human Butyrylcholinesterase as a New-Age Bioscavenger Drug: Development of the Expression System.

RASopathic Skin Eruptions During Vemurafenib Therapy.

Analysis of Novel Melphalan Hydrolysis Products Formed Under Isolated Lung Perfusion Conditions Using Liquid Chromatography/tandem Mass Spectrometry.

Cytochrome P450 2E1 Gene Polymorphisms/Haplotypes and Anti-Tuberculosis Drug-Induced Hepatitis in a Chinese Cohort.

Functional and Structural Neural Network Characterization of Serotonin Transporter Knockout Rats.

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