epithelial cells

Chemotherapy for Cholangiocarcinoma: An Update.

...  for cholangiocarcinoma: An update. World J Gastrointest Oncol. 2013 Jul 15; 5(7): 171-6Ramírez-Merino N, Aix SP, Cortés-Funes H Cholangiocarcinomas (bile duct cancers) are a heterogeneous group of malignancies arising from the epithelial cells of the intrahepatic, perihilar and extrahepatic… Continue reading

Strategies to Increase Drug Penetration in Solid Tumors.

...  led to a longer survival period, the death rate of patients with solid tumors has not changed during the last decades. Emerging studies have identified several physical barriers that limit the therapeutic efficacy of cancer therapeutic agents such as… Continue reading

Mutation in Ribosomal Protein S5 Leads to Spectinomycin Resistance in Neisseria Gonorrhoeae.

...  Lisdahl and Price, 2012), with a special emphasis on recent prospective longitudinal studies (e.g., White et al., 2011; Hicks et al., 2012; Meier et al., 2012). Finally, we will explore potential clinical and public health implications of these findings.… Continue reading

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation.

...  is amenable to adaptation for the sensitive detection of additional emerging resistance mutations in cancer. HubMed – drug   Regulation of the Epithelial-Mesenchymal Transition by Claudin-3 and Claudin-4. PLoS One. 2013; 8(6): e67496Lin X, Shang X, Manorek G, Howell… Continue reading

Pakistan’s Drug Problem.

...  drug problem. Lancet. 2013 Jun 22; 381(9884): 2153-4Yaqub F HubMed – drug   Effects of propofol on damage of rat intestinal epithelial cells induced by heat stress and lipopolysaccharides. Braz J Med Biol Res. 2013 Jun 25; Tang J,… Continue reading

Evaluating Baculovirus as a Vector for Human Prostate Cancer Gene Therapy.

...  prostate biopsies, in two- or three-dimensional cultures, were used. We also evaluated BV in vivo in murine prostate cancer xenograft models. BV was capable of preferentially transducing invasive malignant prostate cancer cell lines compared to early stage cancers and… Continue reading

Tumor Burden Talks in Cancer Treatment With PEGylated Liposomal Drugs.

...  significantly improve locomotor activity and rescue dopaminergic neuronal loss and in Parkinson’s disease rats’ brain. These results indicated the rabies virus glycoprotein peptide modified brain-targeted nanoparticles were promising gene delivery system for RNA interference to achieve anti-apoptotic and anti-inflammation… Continue reading

Histone Acetylation-Mediated Regulation of the Hippo Pathway.

...  M, Wang P, Sun C, He W, Wang F Intestinal barrier dysfunction occurs in many intestinal diseases, in which proinflammatory cytokines play critical roles. However, researchers are still on the way to defining the underlying mechanisms and to evaluate… Continue reading

A Review of Potential Harmful Interactions Between Anticoagulant/Antiplatelet Agents and Chinese Herbal Medicines.

...  CONCLUSIONSSIGNIFICANCE: Conventional anticoagulants and antiplatelet drugs were documented to have harmful interactions with some commonly used single entity CHMs. For those patients who are taking conventional anti-clotting medications with CHMs for cardiovascular or cerebrovascular diseases, the potential risks of… Continue reading

In Vitro Model Systems to Study Androgen Receptor Signaling in Prostate Cancer.

...  to facilitate in vitro investigations into the role of AR signaling in PCa development and progression. These different model systems mimic distinct stages of this heterogeneous disease and exhibit differences with respect to AR expression/status and androgen responsiveness. Technological… Continue reading