cell death

The Influence of Aging on Poststroke Depression Using a Rat Model via Middle Cerebral Artery Occlusion.

The influence of aging on poststroke depression using a rat model via middle cerebral artery occlusion.

Cogn Affect Behav Neurosci. 2013 Jun 13;
Boyko M, Kutz R, Gruenbaum BF, Cohen H, Kozlovsky N, Gruenbaum SE, Shapira Y, Zlotnik A… Continue reading

Animal Models of Nicotine Exposure: Relevance to Second-Hand Smoking, Electronic Cigarette Use, and Compulsive Smoking.

Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking.

Front Psychiatry. 2013; 4: 41
Cohen A, George O

Much evidence indicates that individuals use tobacco primarily to experience the psychopharmacological properties of nicotine… Continue reading

Evaluating Baculovirus as a Vector for Human Prostate Cancer Gene Therapy.

Evaluating baculovirus as a vector for human prostate cancer gene therapy.

PLoS One. 2013; 8(6): e65557
Swift SL, Rivera GC, Dussupt V, Leadley RM, Hudson LC, Ma de Ridder C, Kraaij R, Burns JE, Maitland NJ, Georgopoulos LJ

Gene… Continue reading

Assessing a Potential Role of Host Pannexin 1 During Chlamydia Trachomatis Infection.

Assessing a Potential Role of Host Pannexin 1 during Chlamydia trachomatis Infection.

PLoS One. 2013; 8(5): e63732
McKuen MJ, Dahl G, Fields KA

Pannexin 1 (Panx1) is a plasma membrane channel glycoprotein that plays a role in innate immune… Continue reading

Exploiting Tumor Vulnerabilities: Epigenetics, Cancer Metabolism and the mTOR Pathway in the Era of Personalized Medicine.

Exploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of Personalized Medicine.

Cancer Res. 2013 May 17;
Muñoz-Pinedo C, González-Suárez E, Portela A, Gentilella A, Esteller M

Patient stratification according to drug responses, together with… Continue reading

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(Ethylsulfinyl)-6-(Trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Drug Metab Dispos. 2013 May 7;
Eng H, Sharma R, McDonald TS, Edmonds DJ, Fortin JP, Li X, Stevens… Continue reading

Effects of 5-Fluorouracil in Nuclear and Cellular Morphology, Proliferation, Cell Cycle, Apoptosis, Cytoskeletal and Caveolar Distribution in Primary Cultures of Smooth Muscle Cells.

Effects of 5-Fluorouracil in nuclear and cellular morphology, proliferation, cell cycle, apoptosis, cytoskeletal and caveolar distribution in primary cultures of smooth muscle cells.

PLoS One. 2013; 8(4): e63177
Filgueiras Mde C, Morrot A, Soares PM, Costa ML, Mermelstein C… Continue reading

Suboxone Pharma Foibles/FDA Does Its Job Well.

Suboxone Pharma Foibles/FDA Does Its Job Well.

R I Med J (2013). 2013; 96(4): 13
Gordon A, Kretzschmar A, Gilbert E

HubMed – addiction

 

Pyrvinium targets autophagy addiction to promote cancer cell death.

Cell Death Dis. 2013;… Continue reading

Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions.

Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions.

PLoS One. 2013; 8(4): e62576
D’Agnillo F, Williams MC, Moayeri M, Warfel JM

Vascular leakage pathologies such as pleural effusion and hemorrhage are hallmarks of anthrax pathogenesis. We… Continue reading

Access to Cardiac Rehabilitation Does Not Equate to Attendance.

Access to cardiac rehabilitation does not equate to attendance.

Eur J Cardiovasc Nurs. 2013 Apr 17;
Clark RA, Coffee N, Turner D, Eckert KA, van Gaans D, Wilkinson D, Stewart S, Tonkin AM

Background/Aims:Timely access to appropriate cardiac care… Continue reading