cell death

Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids.

Published August 6, 2013

Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids.

Chem Sci. 2013 Apr 1; 4(4): 1646-1657
Boyer N, Morrison KC, Kim J, Hergenrother PJ, Movassaghi M

The epipolythiodiketopiperazine (ETP) alkaloids are a highly complex class of natural products with potent anticancer… Continue reading →

Use of Micronutrients Attenuates Cannabis and Nicotine Abuse as Evidenced From a Reversal Design: A Case Study.

Published August 3, 2013

Use of micronutrients attenuates cannabis and nicotine abuse as evidenced from a reversal design: a case study.

J Psychoactive Drugs. 2013 Apr-Jun; 45(2): 168-78
Harrison R, Rucklidge JJ, Blampied N

Prior research shows that micronutrients, particularly amino acids, can… Continue reading →

Specific Amino Acids Inhibit Food Intake via the Area Postrema or Vagal Afferents.

Published August 1, 2013

Specific Amino Acids Inhibit Food Intake via the Area Postrema or Vagal Afferents.

J Physiol. 2013 Jul 29;
Jordi J, Herzog B, Camargo SM, Boyle CN, Lutz TA, Verrey F

To maintain nutrient homeostasis the central nervous system integrates… Continue reading →

Antiproliferative Activity of New Benzimidazole Derivatives.

Published July 29, 2013

Antiproliferative activity of new benzimidazole derivatives.

Acta Biochim Pol. 2013 Jul 25;
B?aszczak-?wi?tkiewicz K, Olszewska P, Mikiciuk-Olasik E

A series of new benzimidazole derivatives were synthesized and tested in vitro for possible anticancer activity. Their effect of proliferation into… Continue reading →

Differential Impact of Two Risk Communications on Antipsychotic Prescribing to People With Dementia in Scotland: Segmented Regression Time Series Analysis 2001-2011.

Published July 24, 2013

Differential impact of two risk communications on antipsychotic prescribing to people with dementia in Scotland: segmented regression time series analysis 2001-2011.

PLoS One. 2013; 8(7): e68976
Guthrie B, Clark SA, Reynish EL, McCowan C, Morales DR

Regulatory risk communications… Continue reading →

Bisphosphonate Drug Holiday: Who, When and How Long.

Published July 18, 2013

Bisphosphonate drug holiday: who, when and how long.

Ther Adv Musculoskelet Dis. 2013 Jun; 5(3): 107-11
Diab DL, Watts NB

Bisphosphonates have been widely used in the treatment of osteoporosis with robust data from numerous placebo-controlled trials demonstrating efficacy… Continue reading →

Autophagy in Breast Cancer and Its Implications for Therapy.

Published July 11, 2013

Autophagy in breast cancer and its implications for therapy.

Am J Cancer Res. 2013; 3(3): 251-65
Jain K, Paranandi KS, Sridharan S, Basu A

Autophagy is an evolutionarily conserved process of cellular self-digestion that serves as a mechanism to… Continue reading →

Imaging Tumor Response Following Liver-Directed Intra-Arterial Therapy.

Published June 30, 2013

Imaging tumor response following liver-directed intra-arterial therapy.

Abdom Imaging. 2013 Jun 27;
Guo Y, Yaghmai V, Salem R, Lewandowski RJ, Nikolaidis P, Larson AC, Miller FH

Liver-directed intra-arterial therapies are palliative treatment options for patients with unresectable liver cancer;… Continue reading →

Parthenolide Enhances Dacarbazine Activity Against Melanoma Cells.

Published June 27, 2013

Parthenolide enhances dacarbazine activity against melanoma cells.

Anticancer Drugs. 2013 Jun 21;
Koprowska K, Hartman ML, Sztiller-Sikorska M, Czyz ME

Dacarbazine induces a clinical response only in 15% of melanoma patients. New treatment strategies may involve combinations of drugs… Continue reading →

The Effect of Pioglitazone on the Alzheimer’s Disease-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.

Published June 19, 2013

The effect of pioglitazone on the Alzheimer’s disease-induced apoptosis in human umbilical vein endothelial cells.

Int J Prev Med. 2013 May; 4(Suppl 2): S205-10
Dehghani L, Meamar R, Askari G, Khorvash F, Shaygannejad V, Pour AF, Javanmard SH

Alzheimer’s… Continue reading →