Cell cycle

A Retrospective Audit to Evaluate the Effect of the Change in Midazolam Concentration From 10 Mg/5 Ml to 5 Mg/5 Ml Ampoules on Midazolam Doses Given to Sedation Patients Following the Rapid Response Report (RRR).

A retrospective audit to evaluate the effect of the change in midazolam concentration from 10 mg/5 ml to 5 mg/5 ml ampoules on midazolam doses given to sedation patients following the rapid response report (RRR).

SAAD Dig. 2013 Jan;… Continue reading →

Reduced Susceptibility of Plasmodium Falciparum to Artesunate in Southern Myanmar.

Reduced Susceptibility of Plasmodium falciparum to Artesunate in Southern Myanmar.

PLoS One. 2013; 8(3): e57689
Kyaw MP, Nyunt MH, Chit K, Aye MM, Aye KH, Aye MM, Lindegardh N, Tarning J, Imwong M, Jacob CG, Rasmussen C, Perin J,… Continue reading →

Novel Phenolic Inhibitors of Small/Intermediate-Conductance Ca(2+)-Activated K(+) Channels, KCa3.1 and KCa2.3.

Novel Phenolic Inhibitors of Small/Intermediate-Conductance Ca(2+)-Activated K(+) Channels, KCa3.1 and KCa2.3.

PLoS One. 2013; 8(3): e58614
Oliván-Viguera A, Valero MS, Murillo MD, Wulff H, García-Otín AL, Arbonés-Mainar JM, Köhler R

BACKGROUND: KCa3.1 channels are calcium/calmodulin-regulated voltage-independent K(+) channels that… Continue reading →

Acute Dystonia After Using Single Dose Duloxetine: Case Report.

Acute Dystonia after Using Single Dose Duloxetine: Case Report.

Psychiatry Investig. 2013 Mar; 10(1): 95-97
Karaka? U?urlu G, Onen S, Bay?nd?rl? D, Cayköylü A

Duloxetine is a balanced and potent serotonin and noradrenaline reuptake inhibitor which is known to… Continue reading →

Weak Affinity Chromatography for Evaluation of Stereoisomers in Early Drug Discovery.

Weak Affinity Chromatography for Evaluation of Stereoisomers in Early Drug Discovery.

J Biomol Screen. 2013 Mar 11;
Duong-Thi MD, Bergström M, Fex T, Svensson S, Ohlson S, Isaksson R

In early drug discovery (e.g., in fragment screening), recognition of… Continue reading →

Efficient Generation of Stable Bispecific IgG1 by Controlled Fab-Arm Exchange.

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.

Proc Natl Acad Sci U S A. 2013 Mar 11;
Labrijn AF, Meesters JI, de Goeij BE, van den Bremer ET, Neijssen J, van Kampen MD, Strumane K, Verploegen… Continue reading →

Bioequivalence Study of Pantoprazole Sodium-HPBCD and Conventional Pantoprazole Sodium Enteric-Coated Tablet Formulations.

Bioequivalence Study of Pantoprazole Sodium-HPBCD and Conventional Pantoprazole Sodium Enteric-Coated Tablet Formulations.

ISRN Pharmacol. 2013; 2013: 347457
Kamdi SP, Palkar PJ

The objective of this study was to investigate the bioequivalence of two formulations of 40?mg pantoprazole sodium enteric-coated… Continue reading →

Generation and Validation of a Zebrafish Model of EAST (Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy) Syndrome.

Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome.

Dis Model Mech. 2013 Feb 14;
Mahmood F, Mozere M, Zdebik AA, Stanescu HC, Tobin J, Beales PL, Kleta R, Bockenhauer D, Russell… Continue reading →

Effectiveness of the Histone Deacetylase Inhibitor (S)-2 Against LNCaP and PC3 Human Prostate Cancer Cells.

Effectiveness of the Histone Deacetylase Inhibitor (S)-2 against LNCaP and PC3 Human Prostate Cancer Cells.

PLoS One. 2013; 8(3): e58267
Laurenzana A, Balliu M, Cellai C, Romanelli MN, Paoletti F

Histone deacetylase inhibitors (HDACi) represent a promising class of… Continue reading →

Future Prospects for Pharmacogenetics in the Quest for Personalized Medicine.

Future prospects for pharmacogenetics in the quest for personalized medicine.

J Psychosoc Nurs Ment Health Serv. 2012 Dec; 50(12): 13-6
Howland RH

Understanding pharmacogenetic differences in drug response and tolerability has been an important area of research in personalized… Continue reading →