Cell cycle

Rapid and Selective Access to Three Distinct Sets of Indole-Based Heterocycles From a Single Set of Ugi-Adducts Under Microwave Heating.

Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating.

Chem Commun (Camb). 2013 Mar 1;
Zhang L, Zhao F, Zheng M, Zhai Y, Liu H

Three distinct sets… Continue reading →

Kinetic Modeling-Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.

Kinetic Modeling-Based Detection of Genetic Signatures that Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.

Cancer Res. 2013 Feb 27;
Vera J, Schmitz U, Lai X, Engelmann D, Khan FM, Wolkenhauer O, Putzer BM

Drug resistance is a major cause of… Continue reading →

Drug and Alcohol Rehabilitation: GL3, a Novel 4?-Anilino-4′-O-Demethyl-4-Desoxypodophyllotoxin Analog, Traps Topoisomerase II Cleavage Complexes and Exerts Anticancer Activities.

GL3, a Novel 4?-Anilino-4′-O-Demethyl-4-Desoxypodophyllotoxin Analog, Traps Topoisomerase II Cleavage Complexes and Exerts Anticancer Activities.

Filed under: Drug and Alcohol Rehabilitation

Transl Oncol. 2013 Feb; 6(1): 75-82
Yang XC, Qian SJ, Wang L, Liao SD, Cao J, Hu YZ, He… Continue reading →

Translational Regulation of RPA2 via Internal Ribosomal Entry Site and by eIF3a.

Translational regulation of RPA2 via internal ribosomal entry site and by eIF3a.

Filed under: Drug and Alcohol Rehabilitation

Carcinogenesis. 2013 Feb 7;
Yin JY, Dong ZZ, Liu RY, Chen J, Liu ZQ, Zhang JT

RPA2 is a subunit of… Continue reading →

Striatal Glutamate Release in L-DOPA-Induced Dyskinetic Animals.

Striatal Glutamate Release in l-DOPA-Induced Dyskinetic Animals.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(2): e55706
Nevalainen N, Lundblad M, Gerhardt GA, Strömberg I

l-DOPA-induced dyskinesia is a common side effect developed after chronic treatment with 3,4-dihydroxyphenyl-l-alanine… Continue reading →

Addiction Rehab: Novel Hsp90 Inhibitor NVP-AUY922 Radiosensitizes Prostate Cancer Cells.

Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells.

Filed under: Addiction Rehab

Cancer Biol Ther. 2013 Jan 28; 14(4):
Gandhi N, Wild AT, Chettiar ST, Aziz K, Kato Y, Gajula RP, Williams RD, Cades JA, Annadanam A, Song D,… Continue reading →

Drug and Alcohol Rehabilitation: In Vivo Cell Reprogramming Towards Pluripotency by Virus-Free Overexpression of Defined Factors.

In Vivo Cell Reprogramming towards Pluripotency by Virus-Free Overexpression of Defined Factors.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(1): e54754
Yilmazer A, de Lázaro I, Bussy C, Kostarelos K

The ability to induce the reprogramming of… Continue reading →

Drug and Alcohol Rehabilitation: Bispidine-Amino Acid Conjugates Act as a Novel Scaffold for the Design of Antivirals That Block Japanese Encephalitis Virus Replication.

Bispidine-amino Acid conjugates act as a novel scaffold for the design of antivirals that block Japanese encephalitis virus replication.

Filed under: Drug and Alcohol Rehabilitation

PLoS Negl Trop Dis. 2013 Jan; 7(1): e2005
Haridas V, Rajgokul KS, Sadanandan S,… Continue reading →

Drug and Alcohol Rehabilitation: In Vivo Targeting of ADAM9 Gene Expression Using Lentivirus-Delivered shRNA Suppresses Prostate Cancer Growth by Regulating REG4 Dependent Cell Cycle Progression.

In Vivo Targeting of ADAM9 Gene Expression Using Lentivirus-Delivered shRNA Suppresses Prostate Cancer Growth by Regulating REG4 Dependent Cell Cycle Progression.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(1): e53795
Liu CM, Hsieh CL, He YC, Lo… Continue reading →

Drug and Alcohol Rehabilitation: The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a P53-Dependent Cell Cycle Arrest.

The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(1): e53791
Cui X, Witalison EE, Chumanevich AP, Chumanevich AA, Poudyal… Continue reading →