Comparing the Effectiveness of Acceptance-Based Behavior Therapy and Applied Relaxation on Acceptance of Internal Experiences, Engagement in Valued Actions and Quality of Life in Generalized Anxiety Disorder.
Comparing the effectiveness of acceptance-based behavior therapy and applied relaxation on acceptance of internal experiences, engagement in valued actions and quality of life in generalized anxiety disorder.
J Res Med Sci. 2013 Feb; 18(2): 118-22
Zargar F, Farid AA,… Continue reading
Use of Micronutrients Attenuates Cannabis and Nicotine Abuse as Evidenced From a Reversal Design: A Case Study.
Use of micronutrients attenuates cannabis and nicotine abuse as evidenced from a reversal design: a case study.
J Psychoactive Drugs. 2013 Apr-Jun; 45(2): 168-78
Harrison R, Rucklidge JJ, Blampied N
Prior research shows that micronutrients, particularly amino acids, can… Continue reading
Specific Amino Acids Inhibit Food Intake via the Area Postrema or Vagal Afferents.
Specific Amino Acids Inhibit Food Intake via the Area Postrema or Vagal Afferents.
J Physiol. 2013 Jul 29;
Jordi J, Herzog B, Camargo SM, Boyle CN, Lutz TA, Verrey F
To maintain nutrient homeostasis the central nervous system integrates… Continue reading
The Pharmacists’ Potential to Provide Targets for Interventions to Optimize Pharmacotherapy in Patients With Asthma.
The pharmacists’ potential to provide targets for interventions to optimize pharmacotherapy in patients with asthma.
Int J Clin Pharm. 2013 Jul 26;
van Boven JF, Hiddink EG, Stuurman-Bieze AG, Schuiling-Veninga CC, Postma MJ, Vegter S
Background Despite of pharmacists’ specialized knowledge of medication and his/her regular contact with patients, the expertise of the pharmacist may not be used enough yet. Furthermore, the potential of pharmacy dispensing data is underestimated. Objective To provide targets for tailored interventions in asthma patients and to illustrate the potential value of pharmacists in the identification of these targets using individual pharmacy dispensing data. Setting We performed a cross sectional retrospective analysis assessing the quality of asthma patients’ pharmacotherapeutic treatment. Method Drug dispensing data from 2008 to 2009 were retrieved from a Dutch pharmacy database. All asthma patients were screened for potential suboptimal pharmacotherapy in 2009. Results were projected to a single community pharmacy to provide an estimate of the number of patients eligible for potential interventions. Main outcome measures (1) frequent use of short-acting ?-agonists without preventive medication, (2) concomitant use of ?-blockers, (3) multiple short courses of oral corticosteroids without using inhaled corticosteroids and 4) use of long-acting ?-agonist without inhaled corticosteroids. Results A total of 8,504 patients were eligible for analysis of the quality of their asthma treatment. 20.9 % of all asthma patients used >100 DDD short-acting ?-agonists… Continue reading
Opportunities for Reversible Inhibitors of Monoamine Oxidase-a (RIMAs) in the Treatment of Depression.
Opportunities for reversible inhibitors of monoamine oxidase-A (RIMAs) in the treatment of depression.
CNS Spectr. 2012 Sep; 17(3): 107-20
Lum CT, Stahl SM
Treatment-resistant depression (TRD) may be implicated in 33–57% of depression cases. The currently available effective treatments… Continue reading
SLC1 Glutamate Transporters and Diseases: Psychiatric Diseases and Pathological Pain.
SLC1 Glutamate Transporters and Diseases: Psychiatric Diseases and Pathological Pain.
Curr Mol Pharmacol. 2013 Jul 22;
Nakagawa T, Kaneko S
The solute carrier family 1 (SLC1) consists of two neutral amino acid transporters and five high-affinity excitatory amino acid… Continue reading
Clinical Approach to Fever in the Neurosurgical Intensive Care Unit: Focus on Drug Fever.
Clinical approach to fever in the neurosurgical intensive care unit: Focus on drug fever.
Surg Neurol Int. 2013; 4(Suppl 5): S318-22
Cunha BA
As fever is one of the cardinal signs of infection, the presence of fever in a patient in the neurosurgical intensive care unit (NSICU) raises the question of whether it is infectious in etiology. Infectious and noninfectious causes of fever in the NSICU may be determined based upon assessment of clinical signs and symptoms, the degree of temperature elevation, the relationship of the pulse to the fever (e.g., an infectious process resulting in hyperpyrexia and bradycardia), and when the fever occurs (e.g., related to the length of stay in the NSICU). There are many noninfectious disorders which contribute to temperatures >102°F in the NSICU; these include drug fevers, deep vein thrombosis, phlebitis/pulmonary embolism, acute myocardial infarction, atelectasis, dehydration, acute gout flare, malignancy, acute pancreatitis, transfusion associated hepatitis, and hemorrhage. Infectious rather than noninfectious disorders, however, are more typically associated with high-grade fevers (>102°F.) in the NSICU, and nosocomial pneumonia, (synonymous with ventilator-associated pneumonia [VAP]), is the leading culprit,… Continue reading
Enhanced Bactericidal Potency of Nanoliposomes by Modification of the Fusion Activity Between Liposomes and Bacterium.
Enhanced bactericidal potency of nanoliposomes by modification of the fusion activity between liposomes and bacterium.
Int J Nanomedicine. 2013; 8: 2351-2360
Ma Y, Wang Z, Zhao W, Lu T, Wang R, Mei Q, Chen T
Pseudomonas aeruginosa represents a… Continue reading
Blunted Re-Feeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-Cre-Expressing Neurons.
Blunted Re-feeding Response And Increased Locomotor Activity In Mice Lacking FoxO1 In Synapsin-Cre-Expressing Neurons.
Diabetes. 2013 Jul 8;
Ren H, Plum-Morschel L, Gutierrez-Juarez R, Lu TY, Kim-Muller JY, Heinrich G, Wardlaw SL, Silver R, Accili D
Successful development of… Continue reading