Adverse drug reaction

Tumor Burden Talks in Cancer Treatment With PEGylated Liposomal Drugs.

Tumor Burden Talks in Cancer Treatment with PEGylated Liposomal Drugs.

PLoS One. 2013; 8(5): e63078
Lin YY, Kao HW, Li JJ, Hwang JJ, Tseng YL, Lin WJ, Lin MH, Ting G, Wang HE

PEGylated liposomes are important drug carriers that can passively target tumor by enhanced permeability and retention (EPR) effect in neoplasm lesions. This study demonstrated that tumor burden determines the tumor uptake, and also the tumor response, in cancer treatment with PEGylated liposomal drugs in a C26/tk-luc colon carcinoma-bearing mouse model.Empty PEGylated liposomes (NanoX) and those encapsulated with VNB (NanoVNB) were labeled with In-111 to obtain InNanoX and InVNBL in high labeling yield and radiochemical purity (all >90%). BALB/c mice bearing either small… Continue reading

Evaluation of the Effect of Probiotic (Inersan®) Alone, Combination of Probiotic With Doxycycline and Doxycycline Alone on Aggressive Periodontitis – a Clinical and Microbiological Study.

Evaluation of the effect of probiotic (inersan®) alone, combination of probiotic with doxycycline and doxycycline alone on aggressive periodontitis – a clinical and microbiological study.

J Clin Diagn Res. 2013 Mar; 7(3): 595-600
Shah MP, Gujjari SK, Chandrasekhar VS… Continue reading

Bleeding Complications and Liver Injuries During Phenprocoumon Treatment: A Multicentre Prospective Observational Study in Internal Medicine Departments.

Bleeding complications and liver injuries during phenprocoumon treatment: a multicentre prospective observational study in internal medicine departments.

Dtsch Arztebl Int. 2013 Apr; 110(14): 244-52
Schmiedl S, Rottenkolber M, Szymanski J, Siegmund W, Hippius M, Farker K, Drewelow B, Hasford… Continue reading

Azacitidine in the Management of Patients With Myelodysplastic Syndromes.

Azacitidine in the management of patients with myelodysplastic syndromes.

Ther Adv Hematol. 2012 Dec; 3(6): 355-73
Khan C, Pathe N, Fazal S, Lister J, Rossetti JM

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoeitic disorders characterized by… Continue reading

Serious Treatment Related Adverse Drug Reactions Amongst Anti-Retroviral Naïve MDR-TB Patients.

Serious Treatment Related Adverse Drug Reactions amongst Anti-Retroviral Naïve MDR-TB Patients.

PLoS One. 2013; 8(4): e58817
Van der Walt M, Lancaster J, Odendaal R, Davis JG, Shean K, Farley J

Globally treatment outcomes for multidrug-resistant Mycobacterium tuberculosis (MDR-TB) remain… Continue reading

Antimicrobial Susceptibility and Molecular Subtypes of Staphylococcus Aureus Isolated From Pig Tonsils and Cow’s Milk in China.

Antimicrobial susceptibility and molecular subtypes of Staphylococcus aureus isolated from pig tonsils and cow’s milk in China.

Can J Vet Res. 2012 Oct; 76(4): 268-74
Zhang C, Song L, Chen H, Liu Y, Qin Y, Ning Y

This study… Continue reading

Label-Free Recognition of Drug Resistance via Impedimetric Screening of Breast Cancer Cells.

Label-Free Recognition of Drug Resistance via Impedimetric Screening of Breast Cancer Cells.

PLoS One. 2013; 8(3): e57423
Eker B, Meissner R, Bertsch A, Mehta K, Renaud P

We present a novel study on label-free recognition and distinction of drug… Continue reading

Rapid and Selective Access to Three Distinct Sets of Indole-Based Heterocycles From a Single Set of Ugi-Adducts Under Microwave Heating.

Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating.

Chem Commun (Camb). 2013 Mar 1;
Zhang L, Zhao F, Zheng M, Zhai Y, Liu H

Three distinct sets… Continue reading

Drug and Alcohol Rehabilitation: Evaluation of Linear Classifiers on Articles Containing Pharmacokinetic Evidence of Drug-Drug Interactions.

Evaluation of linear classifiers on articles containing pharmacokinetic evidence of drug-drug interactions.

Filed under: Drug and Alcohol Rehabilitation

Pac Symp Biocomput. 2013; 409-20
Kolchinsky A, Lourenço A, Li L, Rocha LM

Background. Drug-drug interaction (DDI) is a major cause… Continue reading

iADRs: Towards Online Adverse Drug Reaction Analysis.

iADRs: towards online adverse drug reaction analysis.

Filed under: Drug and Alcohol Rehabilitation

Springerplus. 2012 Dec; 1(1): 72
Lin WY, Li HY, Du JW, Feng WY, Lo CF, Soo VW

Adverse Drug Reaction (ADR) is one of the most… Continue reading