Addiction Rehab

KCNQ Channels Regulate Age-Related Memory Impairment.

KCNQ Channels Regulate Age-Related Memory Impairment.

PLoS One. 2013; 8(4): e62445
Cavaliere S, Malik BR, Hodge JJ

In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of… Continue reading →

Substance Use Disorders: Psychoneuroimmunological Mechanisms and New Targets for Therapy.

Substance use disorders: Psychoneuroimmunological mechanisms and new targets for therapy.

Pharmacol Ther. 2013 Apr 27;
Loftis JM, Huckans M

An estimated 76.4 million people worldwide meet criteria for alcohol use disorders, and 15.3 million meet criteria for drug use… Continue reading →

[Neurobiology of Behavioral Addictions.]

[Neurobiology of behavioral addictions.]

Nervenarzt. 2013 Apr 28;
Kiefer F, Fauth-Bühler M, Heinz A, Mann K

Reward learning represents a crucial mechanism in the acquisition and maintenance of addictive behavior. The underlying neurobiological foundations and associated neurobiological pathways are… Continue reading →

School-Based Programmes for Preventing Smoking.

School-based programmes for preventing smoking.

Cochrane Database Syst Rev. 2013; 4: CD001293
Thomas RE, McLellan J, Perera R

Helping young people to avoid starting smoking is a widely endorsed public health goal, and schools provide a route to communicate… Continue reading →

Can MDMA Play a Role in the Treatment of Substance Abuse?

Can MDMA Play a Role in the Treatment of Substance Abuse?

Curr Drug Abuse Rev. 2013 Apr 29;
Jerome L, Shira Schuster MA, Yazar-Klosinski BB

A wider array of treatments are needed for people with substance abuse disorders. Some… Continue reading →

Probing Active Cocaine Vaccination Performance Through Catalytic and Noncatalytic Hapten Design.

Probing Active Cocaine Vaccination Performance through Catalytic and Noncatalytic Hapten Design.

J Med Chem. 2013 Apr 29;
Cai X, Whitfield T, Hixon MS, Grant Y, Koob GF, Janda KD

Presently, there are no FDA-approved medications to treat cocaine addiction.… Continue reading →

Associations Between Morningness/eveningness and Psychopathology: An Epidemiological Survey in Three in-Patient Psychiatric Clinics.

Associations between morningness/eveningness and psychopathology: An epidemiological survey in three in-patient psychiatric clinics.

J Psychiatr Res. 2013 Apr 27;
Lemoine P, Zawieja P, Ohayon MM

OBJECTIVE: This study aims to examine the association between the chronotype (morningness/eveningness) and… Continue reading →

Treatment-Enhanced Paired Action Contributes Substantially to Change Across Multiple Health Behaviors: Secondary Analyses of Five Randomized Trials.

Treatment-enhanced paired action contributes substantially to change across multiple health behaviors: secondary analyses of five randomized trials.

Transl Behav Med. 2013 Mar 1; 3(1): 62-71
Yin HQ, Prochaska JO, Rossi JS, Redding CA, Paiva AL, Blissmer B, Velicer WF,… Continue reading →

First Demonstration That Brain CYP2D-Mediated Opiate Metabolic Activation Alters Analgesia in Vivo.

First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.

Biochem Pharmacol. 2013 Apr 23;
Zhou K, Khokhar JY, Zhao B, Tyndale RF

The response to centrally-acting drugs is highly variable between individuals and does not always… Continue reading →

Cannabinoid and Opioid Interactions: Implications for Opiate Dependence and Withdrawal.

Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal.

Neuroscience. 2013 Apr 24;
Scavone JL, Sterling RC, Van Bockstaele EJ

Withdrawal from opiates, such as heroin or oral narcotics, is characterized by a host of aversive physical and… Continue reading →