Addiction Rehab

KCNQ Channels Regulate Age-Related Memory Impairment.

KCNQ Channels Regulate Age-Related Memory Impairment.

PLoS One. 2013; 8(4): e62445
Cavaliere S, Malik BR, Hodge JJ

In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of… Continue reading

Substance Use Disorders: Psychoneuroimmunological Mechanisms and New Targets for Therapy.

Substance use disorders: Psychoneuroimmunological mechanisms and new targets for therapy.

Pharmacol Ther. 2013 Apr 27;
Loftis JM, Huckans M

An estimated 76.4 million people worldwide meet criteria for alcohol use disorders, and 15.3 million meet criteria for drug use… Continue reading

[Neurobiology of Behavioral Addictions.]

[Neurobiology of behavioral addictions.]

Nervenarzt. 2013 Apr 28;
Kiefer F, Fauth-Bühler M, Heinz A, Mann K

Reward learning represents a crucial mechanism in the acquisition and maintenance of addictive behavior. The underlying neurobiological foundations and associated neurobiological pathways are… Continue reading

School-Based Programmes for Preventing Smoking.

School-based programmes for preventing smoking.

Cochrane Database Syst Rev. 2013; 4: CD001293
Thomas RE, McLellan J, Perera R

Helping young people to avoid starting smoking is a widely endorsed public health goal, and schools provide a route to communicate… Continue reading

Can MDMA Play a Role in the Treatment of Substance Abuse?

Can MDMA Play a Role in the Treatment of Substance Abuse?

Curr Drug Abuse Rev. 2013 Apr 29;
Jerome L, Shira Schuster MA, Yazar-Klosinski BB

A wider array of treatments are needed for people with substance abuse disorders. Some… Continue reading

Probing Active Cocaine Vaccination Performance Through Catalytic and Noncatalytic Hapten Design.

Probing Active Cocaine Vaccination Performance through Catalytic and Noncatalytic Hapten Design.

J Med Chem. 2013 Apr 29;
Cai X, Whitfield T, Hixon MS, Grant Y, Koob GF, Janda KD

Presently, there are no FDA-approved medications to treat cocaine addiction.… Continue reading

Associations Between Morningness/eveningness and Psychopathology: An Epidemiological Survey in Three in-Patient Psychiatric Clinics.

Associations between morningness/eveningness and psychopathology: An epidemiological survey in three in-patient psychiatric clinics.

J Psychiatr Res. 2013 Apr 27;
Lemoine P, Zawieja P, Ohayon MM

OBJECTIVE: This study aims to examine the association between the chronotype (morningness/eveningness) and… Continue reading

Treatment-Enhanced Paired Action Contributes Substantially to Change Across Multiple Health Behaviors: Secondary Analyses of Five Randomized Trials.

Treatment-enhanced paired action contributes substantially to change across multiple health behaviors: secondary analyses of five randomized trials.

Transl Behav Med. 2013 Mar 1; 3(1): 62-71
Yin HQ, Prochaska JO, Rossi JS, Redding CA, Paiva AL, Blissmer B, Velicer WF,… Continue reading

First Demonstration That Brain CYP2D-Mediated Opiate Metabolic Activation Alters Analgesia in Vivo.

First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.

Biochem Pharmacol. 2013 Apr 23;
Zhou K, Khokhar JY, Zhao B, Tyndale RF

The response to centrally-acting drugs is highly variable between individuals and does not always… Continue reading

Cannabinoid and Opioid Interactions: Implications for Opiate Dependence and Withdrawal.

Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal.

Neuroscience. 2013 Apr 24;
Scavone JL, Sterling RC, Van Bockstaele EJ

Withdrawal from opiates, such as heroin or oral narcotics, is characterized by a host of aversive physical and… Continue reading