The Role of FTO Genotype on Eating Behavior in Obese Sardinian Children and Adolescents.

The role of FTO genotype on eating behavior in obese Sardinian children and adolescents.

J Pediatr Endocrinol Metab. 2013 Mar 18; 1-6
Ibba A, Pilia S, Zavattari P, Loche A, Guzzetti C, Casini MR, Minerba L, Loche S

Abstract Aim: We aimed to study the influence of the fat mass and obesity-associated (FTO) gene on eating behavior in 412 obese Sardinian children and adolescents. Genome-wide association studies (GWAS) have identified several susceptibility loci for obesity. Among these, the polymorphisms in the intron 1 of the FTO gene has been found associated to weight gain and obesity in various populations. Methods: All obese patients were genotyped for the FTO single nucleotide polimorphysm (SNP) rs9939609. In all subjects we evaluated eating behavior using the Child Eating Behaviour Questionnaire (CEBQ). Results: We found no differences in eating behavior according to the genotype, either in the entire cohort, or when subjects were subdivided into four different age groups. Conclusions: FTO genotype is associated with body mass index but does not influence eating behavior in a selected cohort of obese children from the isolated genetic population of Sardinia. HubMed – eating


Assessment of the quality of life in maxillectomy patients: A longitudinal study.

J Adv Prosthodont. 2013 Feb; 5(1): 29-35
Kumar P, Alvi HA, Rao J, Singh BP, Jurel SK, Kumar L, Aggarwal H

To longitudinally assess the quality of life in maxillectomy patients rehabilitated with obturator prosthesis.Thirty-six subjects were enrolled in the span of 16 months, out of which six were dropouts. Subjects (age group 20-60 years) with maxillary defects, irrespective of the cause, planned for definite obturator prosthesis, were recruited. The Hindi version of European Organization for Research and Treatment of Cancer, Head and Neck version 1 of Quality of Life Questionnaire was used before surgical intervention and one month after definitive obturator. Questionnaire includes 35 questions related to the patient’s physical health, well being, psychological status, social relation and environmental conditions. The data were processed with statistical package for social science (SPSS). Probability level of P<.05 was considered statistically significant.The quality of life after rehabilitation with obturator prosthesis was 81.48% (±13.64) on average. On item-level, maximum mean scores were obtained for items problem with teeth (1.87 ± 0.94), pain in mouth (1.80 ± 0.92), trouble in eating (1.70 ± 0.88), trouble in talking to other people (1.60 ± 1.22), problems in swallowing solid food (1.57 ± 1.22) and bothering appearance (1.53 ± 1.04); while minimum scores were obtained for the items coughing (1.17 ± 0.38), hoarseness of voice (1.17 ± 0.53), painful throat (1.13 ± 0.43), trouble in having social contacts with friends (1.10 ± 0.40) and trouble having physical contacts with family or friends (1.10 ± 0.31).Obturator prosthesis is a highly positive and non-invasive approach to improve the quality of life of patients with maxillectomy defects. HubMed – eating


Risk factors for ocular toxoplasmosis in Brazil.

Epidemiol Infect. 2013 Mar 18; 1-7
Ferreira AI, De Mattos CC, Frederico FB, Meira CS, Almeida GC, Nakashima F, Bernardo CR, Pereira-Chioccola VL, De Mattos LC

SUMMARY The aim of this study was to investigate risk factors for ocular toxoplasmosis (OT) in patients who received medical attention at a public health service. Three hundred and forty-nine consecutive patients, treated in the Outpatient Eye Clinic of Hospital de Base, São José do Rio Preto, São Paulo state, Brazil, were enrolled in this study. After an eye examination, enzyme-linked immunosorbent assay (ELISA) was used to determine anti-Toxoplasma gondii antibodies. The results showed that 25·5% of the patients were seronegative and 74·5% were seropositive for IgG anti-T. gondii antibodies; of these 27·3% had OT and 72·7% had other ocular diseases (OOD). The presence of cats or dogs [odds ratio (OR) 2·22, 95% confidence interval (CI) 1·24-3·98, P = 0·009] and consumption of raw or undercooked meat (OR 1·77, 95% CI 1·05-2·98, P = 0·03) were associated with infection but not with the development of OT. Age (OT 48·2 ± 21·2 years vs. OOD: 69·5 ± 14·7 years, P < 0·0001) and the low level of schooling/literacy (OT vs. OOD: OR 0·414, 95% CI 0·2231-0·7692, P = 0·007) were associated with OT. The presence of dogs and cats as well as eating raw/undercooked meat increases the risk of infection, but is not associated with the development of OT. HubMed – eating



Types of Eating Disorders – In todays video, Jamie defines the different types of Eating Disorders. Jamie on Youtube – Music by Nathan Wills …