Vascular endothelial growth factor

Metformin Downregulates the Insulin/IGF-I Signaling Pathway and Inhibits Different Uterine Serous Carcinoma (USC) Cells Proliferation and Migration in P53-Dependent or -Independent Manners.

Metformin Downregulates the Insulin/IGF-I Signaling Pathway and Inhibits Different Uterine Serous Carcinoma (USC) Cells Proliferation and Migration in p53-Dependent or -Independent Manners.

PLoS One. 2013; 8(4): e61537
Sarfstein R, Friedman Y, Attias-Geva Z, Fishman A, Bruchim I, Werner H… Continue reading

Access to Cardiac Rehabilitation Does Not Equate to Attendance.

Access to cardiac rehabilitation does not equate to attendance.

Eur J Cardiovasc Nurs. 2013 Apr 17;
Clark RA, Coffee N, Turner D, Eckert KA, van Gaans D, Wilkinson D, Stewart S, Tonkin AM

Background/Aims:Timely access to appropriate cardiac care… Continue reading

Screening of the Antidepressant-Like Effect of the Traditional Chinese Medicinal Formula Si-Ni-San and Their Possible Mechanism of Action in Mice.

Screening of the antidepressant-like effect of the traditional Chinese medicinal formula Si-Ni-San and their possible mechanism of action in mice.

Pharmacognosy Res. 2013 1; 5(1): 36-42
Yi LT, Li J, Liu BB, Li CF

The traditional Chinese medicine formula… Continue reading

Second-Line Treatment of Metastatic Prostate Cancer. Prednisone and Radiotherapy for Symptom Relief.

Second-line treatment of metastatic prostate cancer. Prednisone and radiotherapy for symptom relief.

Prescrire Int. 2013 Mar; 22(136): 74-8

First-line treatment based on androgen suppression is initially very effective in relieving the symptoms of metastatic prostate cancer. When androgen suppression… Continue reading

Will the EU Clinical Trials Regulation Support the Innovative Industry in Bringing New Medicines Faster to Patients?

Will the EU Clinical Trials Regulation Support the Innovative Industry in Bringing New Medicines Faster to Patients?

Pharmaceut Med. 2013 Apr; 27(2): 75-82
Atzor S, Gokhale S, Doherty M

A perspective from the innovative industry is provided in this… Continue reading

Multi Target Neuroprotective and Neurorestorative Anti-Parkinson and Anti-Alzheimer Drugs Ladostigil and M30 Derived From Rasagiline.

Multi target neuroprotective and neurorestorative anti-Parkinson and anti-Alzheimer drugs ladostigil and m30 derived from rasagiline.

Exp Neurobiol. 2013 Mar; 22(1): 1-10
Youdim MB

Present anti-PD and -AD drugs have limited symptomatic activity and devoid of neuroprotective and neurorestorative property… Continue reading

Characteristics of Opioid-Users Whose Death Was Related to Opioid-Toxicity: A Population-Based Study in Ontario, Canada.

Characteristics of opioid-users whose death was related to opioid-toxicity: a population-based study in ontario, Canada.

PLoS One. 2013; 8(4): e60600
Madadi P, Hildebrandt D, Lauwers AE, Koren G

The impact of the prescription opioid public health crisis has been… Continue reading

Toxic Cardiomyopathy Leading to Fatal Acute Cardiac Failure Related to Vandetanib: A Case Report With Histopathological Analysis.

Toxic Cardiomyopathy leading to fatal acute cardiac failure related to vandetanib: a case report with histopathological analysis.

Eur J Endocrinol. 2013 Mar 13;
Scheffel RS, Dora JM, Siqueira DR, Burttet LM, Cerski MR, Maia AL

CONTEXT: Medullary thyroid carcinoma… Continue reading

Propagation of Adult SSCs: From Mouse to Human.

Propagation of Adult SSCs: From Mouse to Human.

Biomed Res Int. 2013; 2013: 384734
Martin LA, Seandel M

Adult spermatogonial stem cells (SSCs) represent a distinctive source of stem cells in mammals for several reasons. First, by giving rise… Continue reading

Rehab Centers: Two Valid Measures of Self-Rated Physical Activity and Capacity.

Two Valid Measures of Self-rated Physical Activity and Capacity.

Filed under: Rehab Centers

Open Cardiovasc Med J. 2012; 6: 156-62
Holen MS, Een R, Mildestvedt T, Eide GE, Meland E

Questionnaires on physical activity (PA) and physical capacity (PC)… Continue reading