Vascular endothelial growth factor

How to Optimize Binding of Coated Nanoparticles: Coupling of Physical Interactions, Molecular Organization and Chemical State.

How to Optimize Binding of Coated Nanoparticles: Coupling of Physical Interactions, Molecular Organization and Chemical State.

Biomater Sci. 2013 Aug 1; 1(8): 814-823
Nap RJ, Szleifer I

One of the key challenges in the development of nano carriers for… Continue reading →

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

PLoS One. 2013; 8(6): e68016
Gründemann C, Thell K, Lengen K, Garcia-Käufer M, Huang YH, Huber R, Craik DJ, Schabbauer G, Gruber CW

Cyclotides are a diverse and abundant… Continue reading →

Critical Appraisal of Ranibizumab in the Treatment of Diabetic Macular Edema.

Critical appraisal of ranibizumab in the treatment of diabetic macular edema.

Clin Ophthalmol. 2013; 7: 1257-67
Stewart MW

Diabetic retinopathy is the leading cause of blindness among individuals of working age in industrialized nations, with most of the vision… Continue reading →

Angiogenesis Inhibitor Bevacizumab Increases the Risk of Ischemic Heart Disease Associated With Chemotherapy: A Meta-Analysis.

Angiogenesis Inhibitor Bevacizumab Increases the Risk of Ischemic Heart Disease Associated with Chemotherapy: A Meta-Analysis.

PLoS One. 2013; 8(6): e66721
Chen XL, Lei YH, Liu CF, Yang QF, Zuo PY, Liu CY, Chen CZ, Liu YW

Concerns have arisen… Continue reading →

Exceptions to and Deviations From the INN Common Stem System.

Exceptions to and deviations from the INN common stem system.

Prescrire Int. 2013 May; 22(138): 138-9

For various reasons, mainly related to the history of the drug and of drug nomenclature, some INNs lack a common stem. As INN… Continue reading →

Parthenolide Enhances Dacarbazine Activity Against Melanoma Cells.

Parthenolide enhances dacarbazine activity against melanoma cells.

Anticancer Drugs. 2013 Jun 21;
Koprowska K, Hartman ML, Sztiller-Sikorska M, Czyz ME

Dacarbazine induces a clinical response only in 15% of melanoma patients. New treatment strategies may involve combinations of drugs… Continue reading →

Update on the Safety and Bioequivalence of Biosimilars – Focus on Enoxaparin.

Update on the safety and bioequivalence of biosimilars – focus on enoxaparin.

Drug Healthc Patient Saf. 2013; 5: 133-141
Jeske W, Walenga JM, Hoppensteadt D, Fareed J

Generic forms of chemically-derived drugs must exhibit chemical identity and be bioequivalent… Continue reading →

The Role of Tumor Tissue Architecture in Treatment Penetration and Efficacy: An Integrative Study.

The role of tumor tissue architecture in treatment penetration and efficacy: an integrative study.

Front Oncol. 2013; 3: 111
Rejniak KA, Estrella V, Chen T, Cohen AS, Lloyd MC, Morse DL

Despite the great progress that has been made… Continue reading →

Comment on “ApoE-Directed Therapeutics Rapidly Clear ?-Amyloid and Reverse Deficits in AD Mouse Models”

Comment on “ApoE-Directed Therapeutics Rapidly Clear ?-Amyloid and Reverse Deficits in AD Mouse Models”

Science. 2013 May 24; 340(6135): 924
Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM

Cramer et al. (Reports, 23… Continue reading →

Polypharmacy in Psychiatry: A Review.

Polypharmacy in psychiatry: a review.

Mens Sana Monogr. 2013 Jan; 11(1): 82-99
Kukreja S, Kalra G, Shah N, Shrivastava A

Psychiatric polypharmacy refers to the prescription of two or more psychiatric medications concurrently to a patient. It can be… Continue reading →