Vascular endothelial growth factor

How to Optimize Binding of Coated Nanoparticles: Coupling of Physical Interactions, Molecular Organization and Chemical State.

How to Optimize Binding of Coated Nanoparticles: Coupling of Physical Interactions, Molecular Organization and Chemical State.

Biomater Sci. 2013 Aug 1; 1(8): 814-823
Nap RJ, Szleifer I

One of the key challenges in the development of nano carriers for… Continue reading

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

PLoS One. 2013; 8(6): e68016
Gründemann C, Thell K, Lengen K, Garcia-Käufer M, Huang YH, Huber R, Craik DJ, Schabbauer G, Gruber CW

Cyclotides are a diverse and abundant… Continue reading

Critical Appraisal of Ranibizumab in the Treatment of Diabetic Macular Edema.

Critical appraisal of ranibizumab in the treatment of diabetic macular edema.

Clin Ophthalmol. 2013; 7: 1257-67
Stewart MW

Diabetic retinopathy is the leading cause of blindness among individuals of working age in industrialized nations, with most of the vision… Continue reading

Angiogenesis Inhibitor Bevacizumab Increases the Risk of Ischemic Heart Disease Associated With Chemotherapy: A Meta-Analysis.

Angiogenesis Inhibitor Bevacizumab Increases the Risk of Ischemic Heart Disease Associated with Chemotherapy: A Meta-Analysis.

PLoS One. 2013; 8(6): e66721
Chen XL, Lei YH, Liu CF, Yang QF, Zuo PY, Liu CY, Chen CZ, Liu YW

Concerns have arisen… Continue reading

Exceptions to and Deviations From the INN Common Stem System.

Exceptions to and deviations from the INN common stem system.

Prescrire Int. 2013 May; 22(138): 138-9

For various reasons, mainly related to the history of the drug and of drug nomenclature, some INNs lack a common stem. As INN… Continue reading

Parthenolide Enhances Dacarbazine Activity Against Melanoma Cells.

Parthenolide enhances dacarbazine activity against melanoma cells.

Anticancer Drugs. 2013 Jun 21;
Koprowska K, Hartman ML, Sztiller-Sikorska M, Czyz ME

Dacarbazine induces a clinical response only in 15% of melanoma patients. New treatment strategies may involve combinations of drugs… Continue reading

Update on the Safety and Bioequivalence of Biosimilars – Focus on Enoxaparin.

Update on the safety and bioequivalence of biosimilars – focus on enoxaparin.

Drug Healthc Patient Saf. 2013; 5: 133-141
Jeske W, Walenga JM, Hoppensteadt D, Fareed J

Generic forms of chemically-derived drugs must exhibit chemical identity and be bioequivalent… Continue reading

The Role of Tumor Tissue Architecture in Treatment Penetration and Efficacy: An Integrative Study.

The role of tumor tissue architecture in treatment penetration and efficacy: an integrative study.

Front Oncol. 2013; 3: 111
Rejniak KA, Estrella V, Chen T, Cohen AS, Lloyd MC, Morse DL

Despite the great progress that has been made… Continue reading

Comment on “ApoE-Directed Therapeutics Rapidly Clear ?-Amyloid and Reverse Deficits in AD Mouse Models”

Comment on “ApoE-Directed Therapeutics Rapidly Clear ?-Amyloid and Reverse Deficits in AD Mouse Models”

Science. 2013 May 24; 340(6135): 924
Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM

Cramer et al. (Reports, 23… Continue reading

Polypharmacy in Psychiatry: A Review.

Polypharmacy in psychiatry: a review.

Mens Sana Monogr. 2013 Jan; 11(1): 82-99
Kukreja S, Kalra G, Shah N, Shrivastava A

Psychiatric polypharmacy refers to the prescription of two or more psychiatric medications concurrently to a patient. It can be… Continue reading