translational research

Protein Kinase C? Is a Modulator of the Dopamine D2 Autoreceptor-Activated Trafficking of the Dopamine Transporter.

Protein kinase C? is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter.

J Neurochem. 2013 Mar 4;
Chen R, Daining CP, Sun H, Fraser R, Stokes SL, Leitges M, Gnegy ME

The strength and duration… Continue reading →

Using the High-Risk Family Design to Identify Biomarkers for Major Depression.

Using the high-risk family design to identify biomarkers for major depression.

Philos Trans R Soc Lond B Biol Sci. 2013; 368(1615): 20120129
Talati A, Weissman MM, Hamilton SP

The familial nature of major depressive disorder (MDD) is now well… Continue reading →

Drug and Alcohol Rehabilitation: Evaluation of Linear Classifiers on Articles Containing Pharmacokinetic Evidence of Drug-Drug Interactions.

Evaluation of linear classifiers on articles containing pharmacokinetic evidence of drug-drug interactions.

Filed under: Drug and Alcohol Rehabilitation

Pac Symp Biocomput. 2013; 409-20
Kolchinsky A, Lourenço A, Li L, Rocha LM

Background. Drug-drug interaction (DDI) is a major cause… Continue reading →

Eating Disorders: Research and Clinical Findings–a Wholistic View.

Research and clinical findings–a wholistic view.

Filed under: Eating Disorders

Int J Orofacial Myology. 2012 Nov; 38: 4-7
Hanson ML

Valuable information is available to clinicians both from research articles, and reports from clinicians. Both sources have limitations. Research,… Continue reading →

Drug and Alcohol Rehabilitation: Doctor Shopping: A Phenomenon of Many Themes.

Doctor Shopping: A Phenomenon of Many Themes.

Filed under: Drug and Alcohol Rehabilitation

Innov Clin Neurosci. 2012 11; 9(11-12): 42-46
Sansone RA, Sansone LA

Doctor shopping is defined as seeing multiple treatment providers, either during a single illness episode… Continue reading →

The MTHFR C677T Variant Is Associated With Responsiveness to Disulfiram Treatment for Cocaine Dependency.

The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency.

Filed under: Addiction Rehab

Front Psychiatry. 2012; 3: 109
Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA

Objective: Disulfiram is a one of… Continue reading →

Prepulse Inhibition in Psychiatric Disorders – Apart From Schizophrenia.

Prepulse inhibition in psychiatric disorders – Apart from schizophrenia.

Filed under: Depression Treatment

J Psychiatr Res. 2012 Dec 31;
Kohl S, Heekeren K, Klosterkötter J, Kuhn J

Prepulse inhibition (PPI) is a robust operational measure of sensorimotor gating. In… Continue reading →

Layer-by-Layer Supramolecular Assemblies Based on Linear and Star-Shaped Poly(glycerol Methacrylate)s for Doxorubicin Delivery.

Layer-by-layer supramolecular assemblies based on linear and star-shaped poly(glycerol methacrylate)s for doxorubicin delivery.

Filed under: Drug and Alcohol Rehabilitation

J Biomed Mater Res A. 2012 Dec 22;
Sun Y, Gao H, Yang YW, Wang A, Wu G, Wang Y,… Continue reading →

Inflammation and Depression: Translating Discoveries Into New Therapeutics – Dr. Scott Russo


 

Inflammation and Depression: Translating Discoveries into New Therapeutics – Dr. Scott Russo – Scott Russo, Ph.D., Johnson & Johnson / IMHRO Rising Star Translational Research Award winner, explains his lab’s discoveries connecting depression with the immune system, suggesting a… Continue reading →

Cognitive Function in an Elderly Population: Interaction Between Vitamin B12 Status, Depression, and Apolipoprotein E {Varepsilon}4: The Hordaland Homocysteine Study.

Cognitive Function in an Elderly Population: Interaction Between Vitamin B12 Status, Depression, and Apolipoprotein E {varepsilon}4: The Hordaland Homocysteine Study.

Filed under: Depression Treatment

Psychosom Med. 2012 Dec 4;
Vogiatzoglou A, Smith AD, Nurk E, Drevon CA, Ueland PM,… Continue reading →