translational research

Protein Kinase C? Is a Modulator of the Dopamine D2 Autoreceptor-Activated Trafficking of the Dopamine Transporter.

Protein kinase C? is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter.

J Neurochem. 2013 Mar 4;
Chen R, Daining CP, Sun H, Fraser R, Stokes SL, Leitges M, Gnegy ME

The strength and duration… Continue reading

Using the High-Risk Family Design to Identify Biomarkers for Major Depression.

Using the high-risk family design to identify biomarkers for major depression.

Philos Trans R Soc Lond B Biol Sci. 2013; 368(1615): 20120129
Talati A, Weissman MM, Hamilton SP

The familial nature of major depressive disorder (MDD) is now well… Continue reading

Drug and Alcohol Rehabilitation: Evaluation of Linear Classifiers on Articles Containing Pharmacokinetic Evidence of Drug-Drug Interactions.

Evaluation of linear classifiers on articles containing pharmacokinetic evidence of drug-drug interactions.

Filed under: Drug and Alcohol Rehabilitation

Pac Symp Biocomput. 2013; 409-20
Kolchinsky A, Lourenço A, Li L, Rocha LM

Background. Drug-drug interaction (DDI) is a major cause… Continue reading

Eating Disorders: Research and Clinical Findings–a Wholistic View.

Research and clinical findings–a wholistic view.

Filed under: Eating Disorders

Int J Orofacial Myology. 2012 Nov; 38: 4-7
Hanson ML

Valuable information is available to clinicians both from research articles, and reports from clinicians. Both sources have limitations. Research,… Continue reading

Drug and Alcohol Rehabilitation: Doctor Shopping: A Phenomenon of Many Themes.

Doctor Shopping: A Phenomenon of Many Themes.

Filed under: Drug and Alcohol Rehabilitation

Innov Clin Neurosci. 2012 11; 9(11-12): 42-46
Sansone RA, Sansone LA

Doctor shopping is defined as seeing multiple treatment providers, either during a single illness episode… Continue reading

The MTHFR C677T Variant Is Associated With Responsiveness to Disulfiram Treatment for Cocaine Dependency.

The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency.

Filed under: Addiction Rehab

Front Psychiatry. 2012; 3: 109
Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA

Objective: Disulfiram is a one of… Continue reading

Prepulse Inhibition in Psychiatric Disorders – Apart From Schizophrenia.

Prepulse inhibition in psychiatric disorders – Apart from schizophrenia.

Filed under: Depression Treatment

J Psychiatr Res. 2012 Dec 31;
Kohl S, Heekeren K, Klosterkötter J, Kuhn J

Prepulse inhibition (PPI) is a robust operational measure of sensorimotor gating. In… Continue reading

Layer-by-Layer Supramolecular Assemblies Based on Linear and Star-Shaped Poly(glycerol Methacrylate)s for Doxorubicin Delivery.

Layer-by-layer supramolecular assemblies based on linear and star-shaped poly(glycerol methacrylate)s for doxorubicin delivery.

Filed under: Drug and Alcohol Rehabilitation

J Biomed Mater Res A. 2012 Dec 22;
Sun Y, Gao H, Yang YW, Wang A, Wu G, Wang Y,… Continue reading

Inflammation and Depression: Translating Discoveries Into New Therapeutics – Dr. Scott Russo


 

Inflammation and Depression: Translating Discoveries into New Therapeutics – Dr. Scott Russo – Scott Russo, Ph.D., Johnson & Johnson / IMHRO Rising Star Translational Research Award winner, explains his lab’s discoveries connecting depression with the immune system, suggesting a… Continue reading

Cognitive Function in an Elderly Population: Interaction Between Vitamin B12 Status, Depression, and Apolipoprotein E {Varepsilon}4: The Hordaland Homocysteine Study.

Cognitive Function in an Elderly Population: Interaction Between Vitamin B12 Status, Depression, and Apolipoprotein E {varepsilon}4: The Hordaland Homocysteine Study.

Filed under: Depression Treatment

Psychosom Med. 2012 Dec 4;
Vogiatzoglou A, Smith AD, Nurk E, Drevon CA, Ueland PM,… Continue reading