Drug and Alcohol Rehabilitation: Comparison of Aerobic Conjunctival Bacterial Flora in Pregnant, Reproductive-Aged and Postmenopausal Women.
Comparison of aerobic conjunctival bacterial flora in pregnant, reproductive-aged and postmenopausal women.
Filed under: Drug and Alcohol Rehabilitation
Int J Ophthalmol. 2012; 5(6): 731-6
Balikoglu-Yilmaz M, Sen E, Sevket O, Polat Y, Karabulut A, Uysal O
To evaluate the effect of hormonal status on aerobic conjunctival flora in women.One hundred fifty-eight women [reproductive-aged (n=55), pregnant (n=51), and postmenopausal (n=52)] who admitted to outpatient clinic of Obstetrics and Gynecology Department of Denizli State Hospital were enrolled. Age, body-mass index (BMI), obstetric history, cigarette smoking, drug usage, presence of systemic disease, and intraocular pressure (IOP) were recorded for each patient. The samples were taken from the lower fornix with two culture swabs and directly incubated in culture containing 5% sheep blood, eosin-methylene blue and chocolate agar. The other swab specimen was Gram stained. All growths and microscopic results were analyzed.The coagulase-negative Staphylococcus was the predominant organism isolated in the conjunctival samples in both three groups. The aerobic microorganism growth rate for all isolated aerobic organisms revealed no significant change in the three groups (P >0.05). The conjunctival culture positivity rates were similar in the three groups (49% in reproductive-aged, 57% in pregnant and 58% in postmenopausal women) (P >0.05). Age, IOP,… Continue reading
Parametric Model of Combination Therapy for Non-Hodgkin Lymphoma.
Parametric model of combination therapy for non-hodgkin lymphoma.
Filed under: Drug and Alcohol Rehabilitation
PLoS One. 2012; 7(12): e51736
Weiss RF, Miller MG, Cronin JF, Hensley HH, Joshi ID, Smith MR
The development and clinical testing of drug combinations… Continue reading
Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model With Decreased Sensitivity to Histone Deacetylase Inhibition.
Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model with Decreased Sensitivity to Histone Deacetylase Inhibition.
Filed under: Drug and Alcohol Rehabilitation
PLoS One. 2012; 7(12): e52335
Smith SJ, Wilson M, Ward JH, Rahman CV,… Continue reading
Drug and Alcohol Rehabilitation: Murine Atrial HL-1 Cell Line Is a Reliable Model to Study Drug Metabolizing Enzymes in the Heart.
Murine Atrial HL-1 Cell Line is a Reliable Model to Study Drug Metabolizing Enzymes in the Heart.
Filed under: Drug and Alcohol Rehabilitation
Vascul Pharmacol. 2012 Dec 22;
Elshenawy OH, Anwar-Mohamed A, Abdelhamid G, El-Kadi AO
HL-1 cells are… Continue reading
Use of an Algorithm for Identifying Hidden Drug-Drug Interactions in Adverse Event Reports.
Use of an algorithm for identifying hidden drug-drug interactions in adverse event reports.
Filed under: Drug and Alcohol Rehabilitation
J Am Med Inform Assoc. 2012 Dec 25;
Gooden KM, Pan X, Kawabata H, Heim JM
Drug and Alcohol Rehabilitation: Inducible Nitric Oxide Synthase Haplotype Associated With Hypertension and Responsiveness to Antihypertensive Drug Therapy.
Inducible nitric oxide synthase haplotype associated with hypertension and responsiveness to antihypertensive drug therapy.
Filed under: Drug and Alcohol Rehabilitation
Gene. 2012 Dec 21;
Oliveira-Paula GH, Lacchini R, Coeli-Lacchini FB, Junior HM, Tanus-Santos JE
Hypertension is a multifactorial disorder associated with increased inducible nitric oxide synthase (iNOS) expression and activity. While genetic polymorphisms affect iNOS expression, it is not known whether iNOS gene polymorphisms affect the susceptibility to hypertension and the responses to antihypertensive therapy. This study aimed at assessing whether iNOS polymorphisms ((CCTTT)(n), g.-1026C>A, and g.2087G>A) and haplotypes are associated with hypertension and with responsiveness to drug therapy. We studied 115 well controlled hypertensive patients (HTN), 82 hypertensive patients resistant to optimized antihypertensive therapy (RHTN), and 113 normotensive healthy subjects (NT). Genotypings were carried out using real-time polymerase chain reaction (PCR) and PCR amplification followed by capillary electrophoresis. The software PHASE 2.1 was used to estimate the haplotypes frequencies in each group. Variant genotypes (GA+AA) for the g.2087G>A polymorphism were more commonly found in hypertensive patients (HTN+RHTN) than in normotensives (P=0.016; OR=2.05). We found no associations between genotypes and responsiveness to therapy (P>0.05). The S-C-A haplotype was more commonly found in hypertensive patients (HTN+RHTN) than in normotensives (P=0.014; OR=6.07). Interestingly, this haplotype was more commonly found in the HTN group than in the RHTN group (P=0.012; OR=0.14). Our findings indicate that the g.2087G>A polymorphism in the iNOS… Continue reading
Depression Support Groups
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Support groups
Filed under: depression support groups
A depression/bipolar support… Continue reading
Depression Treatment: [Diagnosis and Treatment of Anxiety-Depressive Disorders in Patients With Myocardial Infarction.]
[Diagnosis and treatment of anxiety-depressive disorders in patients with myocardial infarction.]
Filed under: Depression Treatment
Zh Nevrol Psikhiatr Im S S Korsakova. 2012; 112(11 Vypusk 2 Depressija): 91-95
Semiglazova MV, Krasnov VN, Dovzhenko TV, Lebedev AV
The results of… Continue reading