PLoS One

Deoxyhypusine Hydroxylase From Plasmodium Vivax, the Neglected Human Malaria Parasite: Molecular Cloning, Expression and Specific Inhibition by the 5-LOX Inhibitor Zileuton.

Deoxyhypusine Hydroxylase from Plasmodium vivax, the Neglected Human Malaria Parasite: Molecular Cloning, Expression and Specific Inhibition by the 5-LOX Inhibitor Zileuton.

PLoS One. 2013; 8(3): e58318
Atemnkeng VA, Pink M, Schmitz-Spanke S, Wu XJ, Dong LL, Zhao KH, May… Continue reading

Predicting Where Small Molecules Bind at Protein-Protein Interfaces.

Predicting where Small Molecules Bind at Protein-Protein Interfaces.

PLoS One. 2013; 8(3): e58583
Walter P, Metzger J, Thiel C, Helms V

Small molecules that bind at protein-protein interfaces may either block or stabilize protein-protein interactions in cells. Thus, some… Continue reading

Stroke in a Patient With Tuberculous Meningitis and HIV Infection.

Stroke in a Patient with Tuberculous Meningitis and HIV Infection.

Mediterr J Hematol Infect Dis. 2013; 5(1): e2013017
Pasticci MB, Paciaroni M, Floridi P, Cecchini E, Baldelli F

Tuberculous meningitis (TBM) is a devastating disease. TBM occurs more commonly… Continue reading

The Puzzle of Neuroimaging and Psychiatric Diagnosis: Technology and Nosology in an Evolving Discipline.

The Puzzle of Neuroimaging and Psychiatric Diagnosis: Technology and Nosology in an Evolving Discipline.

AJOB Neurosci. 2012 Oct 1; 3(4): 31-41
Farah MJ, Gillihan SJ

Brain imaging provides ever more sensitive measures of structure and function relevant to human… Continue reading

Genetic Variants of Uncoupling Proteins-2 and -3 in Relation to Maximal Oxygen Uptake in Different Sports.

Genetic variants of uncoupling proteins-2 and -3 in relation to maximal oxygen uptake in different sports.

Acta Biochim Pol. 2013 Mar 15;
Holdys J, Gronek P, Kry?ciak J, Stanis?awski D

Uncoupling proteins 2 and 3 (UCP2 and UCP3) as mitochondrial electron transporters are involved in regulation of ATP production and energy dissipation as heat. Energy efficiency plays an important role in physical performance, especially in aerobic fitness. The aim of this study was to examine the association between maximal oxygen uptake and genetic variants of the UCP2 and UCP3 genes. The studies were carried out in a group of 154 men and 85 women, professional athletes representing various sports and fitness levels and students of the University of Physical Education in Pozna?. Physiological and molecular procedures were used, i.e. direct measurement of maximum oxygen uptake (VO2max) and analysis of an insertion/deletion (I/D) polymorphism in the 3’untranslated region of exon 8 of the UCP2 gene and a C\>T substitution in exon 5 (Y210Y) of the UCP3… Continue reading

Protein-Protein Docking With F2Dock 2.0 and GB-Rerank.

Protein-Protein Docking with F2Dock 2.0 and GB-Rerank.

PLoS One. 2013; 8(3): e51307
Chowdhury R, Rasheed M, Keidel D, Moussalem M, Olson A, Sanner M, Bajaj C

Computational simulation of protein-protein docking can expedite the process of molecular modeling and… Continue reading

Label-Free Recognition of Drug Resistance via Impedimetric Screening of Breast Cancer Cells.

Label-Free Recognition of Drug Resistance via Impedimetric Screening of Breast Cancer Cells.

PLoS One. 2013; 8(3): e57423
Eker B, Meissner R, Bertsch A, Mehta K, Renaud P

We present a novel study on label-free recognition and distinction of drug… Continue reading

Control of (Multi)Drug Resistance and Tuberculosis Incidence Over 23 Years in the Context of a Well-Supported Tuberculosis Programme in Rural Malawi.

Control of (Multi)Drug Resistance and Tuberculosis Incidence over 23 Years in the Context of a Well-Supported Tuberculosis Programme in Rural Malawi.

PLoS One. 2013; 8(3): e58192
Mboma SM, Houben RM, Glynn JR, Sichali L, Drobniewski F, Mpunga J, Fine… Continue reading

Propagation of Adult SSCs: From Mouse to Human.

Propagation of Adult SSCs: From Mouse to Human.

Biomed Res Int. 2013; 2013: 384734
Martin LA, Seandel M

Adult spermatogonial stem cells (SSCs) represent a distinctive source of stem cells in mammals for several reasons. First, by giving rise… Continue reading

Evening Chronotype Is Associated With Changes in Eating Behavior, More Sleep Apnea, and Increased Stress Hormones in Short Sleeping Obese Individuals.

Evening Chronotype Is Associated with Changes in Eating Behavior, More Sleep Apnea, and Increased Stress Hormones in Short Sleeping Obese Individuals.

PLoS One. 2013; 8(3): e56519
Lucassen EA, Zhao X, Rother KI, Mattingly MS, Courville AB, de Jonge L,… Continue reading