High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound With Anti-Diabetic Efficacy in Db/db Mice.
High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound with Anti-Diabetic Efficacy in db/db Mice.
PLoS One. 2013; 8(5): e63861
Zhang M, Feng Y, Wang J, Zhao J, Li T, He M, Yang D, Nosjean O, Boutin J, Renard… Continue reading
Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(Ethylsulfinyl)-6-(Trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.
Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.
Drug Metab Dispos. 2013 May 7;
Eng H, Sharma R, McDonald TS, Edmonds DJ, Fortin JP, Li X, Stevens… Continue reading
Differential Targeting of Brain Stress Circuits With a Selective Glucocorticoid Receptor Modulator.
Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator.
Proc Natl Acad Sci U S A. 2013 Apr 23;
Zalachoras I, Houtman R, Atucha E, Devos R, Tijssen AM, Hu P, Lockey PM, Datson NA, Belanoff… Continue reading
Addiction Rehab: Peroxisome Proliferator Activated Receptor-?/Hypoxia Inducible Factor-1? Interplay Sustains Carbonic Anhydrase IX and Apoliprotein E Expression in Breast Cancer Stem Cells.
Peroxisome Proliferator Activated Receptor-?/Hypoxia Inducible Factor-1? Interplay Sustains Carbonic Anhydrase IX and Apoliprotein E Expression in Breast Cancer Stem Cells.
Filed under: Addiction Rehab
PLoS One. 2013; 8(1): e54968
Papi A, Storci G, Guarnieri T, De Carolis S, Bertoni… Continue reading
Addiction Rehab: Novel Hsp90 Inhibitor NVP-AUY922 Radiosensitizes Prostate Cancer Cells.
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells.
Filed under: Addiction Rehab
Cancer Biol Ther. 2013 Jan 28; 14(4):
Gandhi N, Wild AT, Chettiar ST, Aziz K, Kato Y, Gajula RP, Williams RD, Cades JA, Annadanam A, Song D,… Continue reading
Drug and Alcohol Rehabilitation: Murine Atrial HL-1 Cell Line Is a Reliable Model to Study Drug Metabolizing Enzymes in the Heart.
Murine Atrial HL-1 Cell Line is a Reliable Model to Study Drug Metabolizing Enzymes in the Heart.
Filed under: Drug and Alcohol Rehabilitation
Vascul Pharmacol. 2012 Dec 22;
Elshenawy OH, Anwar-Mohamed A, Abdelhamid G, El-Kadi AO
HL-1 cells are… Continue reading