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The Role of FTO Genotype on Eating Behavior in Obese Sardinian Children and Adolescents.

The role of FTO genotype on eating behavior in obese Sardinian children and adolescents.

J Pediatr Endocrinol Metab. 2013 Mar 18; 1-6
Ibba A, Pilia S, Zavattari P, Loche A, Guzzetti C, Casini MR, Minerba L, Loche S

Abstract… Continue reading

The Glucocorticoid Antagonist RU-486 Suppresses HIV Infectivity and Replication.

The Glucocorticoid Antagonist RU-486 Suppresses HIV Infectivity and Replication.

J Neuropsychiatry Clin Neurosci. 2013 Mar 1; 25(1): 51-7
Benton TD, Lynch KG, Dubé B, Gettes DR, Tustin NB, Metzger DS, Blume J, Douglas SD, Evans DL

The effects of… Continue reading

Postural Strategy and Back Muscle Oxygenation During Inspiratory Muscle Loading.

Postural Strategy and Back Muscle Oxygenation During Inspiratory Muscle Loading.

Med Sci Sports Exerc. 2013 Mar 6;
Janssens L, Pijnenburg M, Claeys K, McConnell A, Troosters T, Brumagne S

PURPOSE: Most healthy individuals show a multi-segmental control strategy during… Continue reading

Double Trouble: Does Co-Morbid Chronic Somatic Illness Increase Risk for Recurrence in Depression? a Systematic Review.

Double trouble: does co-morbid chronic somatic illness increase risk for recurrence in depression? A systematic review.

PLoS One. 2013; 8(3): e57510
Kok GD, Bockting CL, Burger H, Hannig W, Pijnenborg GH, Cuijpers P, Hollon SD

To perform a systematic… Continue reading

Monetary Reward Processing in Obese Individuals With and Without Binge Eating Disorder.

Monetary Reward Processing in Obese Individuals With and Without Binge Eating Disorder.

Biol Psychiatry. 2013 Feb 23;
Balodis IM, Kober H, Worhunsky PD, White MA, Stevens MC, Pearlson GD, Sinha R, Grilo CM, Potenza MN

BACKGROUND: An important step… Continue reading

Cortico-Limbic Responsiveness to High-Calorie Food Images Predicts Weight Status Among Women.

Cortico-limbic responsiveness to high-calorie food images predicts weight status among women.

Int J Obes (Lond). 2013 Mar 5;
Killgore WD, Weber M, Schwab ZJ, Kipman M, Deldonno SR, Webb CA, Rauch SL

Objectives:Excessive weight gain and obesity are currently… Continue reading

Muscarinic Acetylcholine Receptor Activation Prevents Disinhibition-Mediated LTP in the Hippocampus.

Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus.

Front Cell Neurosci. 2013; 7: 16
Takkala P, Woodin MA

Disinhibition-mediated long-term potentiation (LTP) in the CA1 region of the hippocampus involves GABAergic synaptic plasticity at feedforward inhibitory inputs,… Continue reading

Gene-Environment Interactions in Major Depressive Disorder.

Gene-environment interactions in major depressive disorder.

Can J Psychiatry. 2013 Feb; 58(2): 76-83
Klengel T, Binder EB

Family, twin, and epidemiologic studies have suggested that both genes and environment are important risk factors for the development of major depressive… Continue reading

Depression Treatment: Characteristics of Pain in Hospitalized Medical Patients, Surgical Patients, and Outpatients Attending a Pain Management Centre.

Characteristics of pain in hospitalized medical patients, surgical patients, and outpatients attending a pain management centre.

Filed under: Depression Treatment

Br J Anaesth. 2013 Feb 18;
Rockett MP, Simpson G, Crossley R, Blowey S

BACKGROUND: /st>The characteristics and psychological impact of pain suffered by medical inpatients has been relatively under-investigated. The aim of this study was to compare the pain experience of medical, surgical inpatients, and patients attending a pain management centre. Some aspects of the quality of pain scoring and prescribing were also audited. METHODS: /st>Medical inpatients with significant pain (moderate or severe pain on a verbal rating scale) were assessed using a battery of psychometric questionnaires. Comparator samples of surgical inpatients and patients attending the pain management centre were recruited. RESULTS: /st>The prevalence of significant pain did not differ between the medical group (n=37) and the surgical group (n=38) (16.7% and 19.9%). Chronic pain was common in the medical group (54%) and the surgical group (50%). There were no differences in psychometric variables between the medical and surgical groups. Clinically significant scores for anxiety and depression (HADS ?11) were common in all groups (30-38%). There was less concordance between patient-reported pain scores and nurse-recorded pain scores in the medical group than the surgical group and analgesic prescribing differed between the two groups. CONCLUSIONS: /st>The characteristics of pain in… Continue reading

Towards Personalizing Treatment for Depression : Developing Treatment Values Markers.

Towards Personalizing Treatment for Depression : Developing Treatment Values Markers.

Filed under: Depression Treatment

Patient. 2013 Feb 19;
Wittink MN, Morales KH, Cary M, Gallo JJ, Bartels SJ

BACKGROUND: While ‘personalized medicine’ commonly refers to genetic markers or profiles… Continue reading