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The Role of FTO Genotype on Eating Behavior in Obese Sardinian Children and Adolescents.

The role of FTO genotype on eating behavior in obese Sardinian children and adolescents.

J Pediatr Endocrinol Metab. 2013 Mar 18; 1-6
Ibba A, Pilia S, Zavattari P, Loche A, Guzzetti C, Casini MR, Minerba L, Loche S

Abstract… Continue reading →

The Glucocorticoid Antagonist RU-486 Suppresses HIV Infectivity and Replication.

The Glucocorticoid Antagonist RU-486 Suppresses HIV Infectivity and Replication.

J Neuropsychiatry Clin Neurosci. 2013 Mar 1; 25(1): 51-7
Benton TD, Lynch KG, Dubé B, Gettes DR, Tustin NB, Metzger DS, Blume J, Douglas SD, Evans DL

The effects of… Continue reading →

Postural Strategy and Back Muscle Oxygenation During Inspiratory Muscle Loading.

Postural Strategy and Back Muscle Oxygenation During Inspiratory Muscle Loading.

Med Sci Sports Exerc. 2013 Mar 6;
Janssens L, Pijnenburg M, Claeys K, McConnell A, Troosters T, Brumagne S

PURPOSE: Most healthy individuals show a multi-segmental control strategy during… Continue reading →

Double Trouble: Does Co-Morbid Chronic Somatic Illness Increase Risk for Recurrence in Depression? a Systematic Review.

Double trouble: does co-morbid chronic somatic illness increase risk for recurrence in depression? A systematic review.

PLoS One. 2013; 8(3): e57510
Kok GD, Bockting CL, Burger H, Hannig W, Pijnenborg GH, Cuijpers P, Hollon SD

To perform a systematic… Continue reading →

Monetary Reward Processing in Obese Individuals With and Without Binge Eating Disorder.

Monetary Reward Processing in Obese Individuals With and Without Binge Eating Disorder.

Biol Psychiatry. 2013 Feb 23;
Balodis IM, Kober H, Worhunsky PD, White MA, Stevens MC, Pearlson GD, Sinha R, Grilo CM, Potenza MN

BACKGROUND: An important step… Continue reading →

Cortico-Limbic Responsiveness to High-Calorie Food Images Predicts Weight Status Among Women.

Cortico-limbic responsiveness to high-calorie food images predicts weight status among women.

Int J Obes (Lond). 2013 Mar 5;
Killgore WD, Weber M, Schwab ZJ, Kipman M, Deldonno SR, Webb CA, Rauch SL

Objectives:Excessive weight gain and obesity are currently… Continue reading →

Muscarinic Acetylcholine Receptor Activation Prevents Disinhibition-Mediated LTP in the Hippocampus.

Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus.

Front Cell Neurosci. 2013; 7: 16
Takkala P, Woodin MA

Disinhibition-mediated long-term potentiation (LTP) in the CA1 region of the hippocampus involves GABAergic synaptic plasticity at feedforward inhibitory inputs,… Continue reading →

Gene-Environment Interactions in Major Depressive Disorder.

Gene-environment interactions in major depressive disorder.

Can J Psychiatry. 2013 Feb; 58(2): 76-83
Klengel T, Binder EB

Family, twin, and epidemiologic studies have suggested that both genes and environment are important risk factors for the development of major depressive… Continue reading →

Depression Treatment: Characteristics of Pain in Hospitalized Medical Patients, Surgical Patients, and Outpatients Attending a Pain Management Centre.

Characteristics of pain in hospitalized medical patients, surgical patients, and outpatients attending a pain management centre.

Filed under: Depression Treatment

Br J Anaesth. 2013 Feb 18;
Rockett MP, Simpson G, Crossley R, Blowey S

BACKGROUND: /st>The characteristics and psychological impact of pain suffered by medical inpatients has been relatively under-investigated. The aim of this study was to compare the pain experience of medical, surgical inpatients, and patients attending a pain management centre. Some aspects of the quality of pain scoring and prescribing were also audited. METHODS: /st>Medical inpatients with significant pain (moderate or severe pain on a verbal rating scale) were assessed using a battery of psychometric questionnaires. Comparator samples of surgical inpatients and patients attending the pain management centre were recruited. RESULTS: /st>The prevalence of significant pain did not differ between the medical group (n=37) and the surgical group (n=38) (16.7% and 19.9%). Chronic pain was common in the medical group (54%) and the surgical group (50%). There were no differences in psychometric variables between the medical and surgical groups. Clinically significant scores for anxiety and depression (HADS ?11) were common in all groups (30-38%). There was less concordance between patient-reported pain scores and nurse-recorded pain scores in the medical group than the surgical group and analgesic prescribing differed between the two groups. CONCLUSIONS: /st>The characteristics of pain in… Continue reading →

Towards Personalizing Treatment for Depression : Developing Treatment Values Markers.

Towards Personalizing Treatment for Depression : Developing Treatment Values Markers.

Filed under: Depression Treatment

Patient. 2013 Feb 19;
Wittink MN, Morales KH, Cary M, Gallo JJ, Bartels SJ

BACKGROUND: While ‘personalized medicine’ commonly refers to genetic markers or profiles… Continue reading →