Neurological Disorders

Do You Think Hording Is a Mental Disease or Do You Think Its Laziness?

Question by Friend: Do you think hording is a mental disease or do you think its laziness?
I am watching Hording: Buried Alive on TLC and they say hording/ocd is a mental disease. But I really think it is laziness.… Continue reading

Deep Brain Procedure Makes Debut Locally

Deep brain procedure makes debut locally
The diodes emit an electric pulse into parts of the brain such as the thalamus (a sort of switchboard in the brain that relays sensory information) that can lessen the effects of neurological disorders… Continue reading

Another Tragedy of Perinatal Illness

Another Tragedy of Perinatal Illness
We need to continue to educate the public and the media so that they know the signs and symptoms of postpartum depression and anxiety disorders and the more severe symptoms of postpartum psychosis. It makes… Continue reading

Depression Treatment Device Co Brainsway Raises NIS 24m

Depression treatment device co Brainsway raises NIS 24m
The payment is for exclusive rights to distribute Brainsway's systems for treating depression and is the first of two such payments. Brainsway is engaged in R&D and sales of medical equipment for… Continue reading

Susceptibility Genes Are Enriched in Those of the HSV-1/host Interactome in Psychiatric and Neurological Disorders.

Susceptibility genes are enriched in those of the HSV-1/host interactome in psychiatric and neurological disorders.

Pathog Dis. 2013 Aug 3;
Carter CJ

Herpes simplex (HSV-1) can promote beta-amyloid deposition and tau phosphorylation, demyelination or cognitive deficits relevant to Alzheimer’s disease or multiple sclerosis and to many neuropsychiatric disorders with which it has been implicated. A seroprevalence much higher than disease incidence has called into question any primary causal role. However, as also the case with risk promoting polymorphisms, (also present in control populations) any causal effects are likely to be conditional. During its life cycle, the virus binds to many proteins and modifies the expression of multiple genes creating a host/pathogen interactome involving 1347 host genes. This dataset is heavily enriched in the susceptibility genes for multiple sclerosis (P= 1.3E-99) >Alzheimer’s disease > schizophrenia > Parkinsonism > depression> bipolar disorder> childhood obesity> chronic fatigue> autism > and anorexia (P=0.047) but not ADHD, a relationship maintained for GWAS datasets in multiple sclerosis and Alzheimer’s… Continue reading

Training-Induced Behavioral and Brain Plasticity in Inhibitory Control.

Training-induced behavioral and brain plasticity in inhibitory control.

Front Hum Neurosci. 2013; 7: 427
Spierer L, Chavan CF, Manuel AL

Deficits in inhibitory control, the ability to suppress ongoing or planned motor or cognitive processes, contribute to many psychiatric… Continue reading

Thursday April 14 on the Dr. Phil Show: Young Women in Trouble

Thursday April 14 on The Dr. Phil Show: Young Women in Trouble
Liz shares the shocking way she copes with her grief after the death of her baby boy. And, see an update on Meagan, who was struggling with a… Continue reading

The Size, Burden and Cost of Disorders of the Brain in the UK.

The size, burden and cost of disorders of the brain in the UK.

J Psychopharmacol. 2013 Jul 24;
Fineberg NA, Haddad PM, Carpenter L, Gannon B, Sharpe R, Young AH, Joyce E, Rowe J, Wellsted D, Nutt D, Sahakian… Continue reading

Zinc Homeostasis and Neurodegenerative Disorders.

Zinc homeostasis and neurodegenerative disorders.

Front Aging Neurosci. 2013; 5: 33
Szewczyk B

Zinc is an essential trace element, whose importance to the function of the central nervous system (CNS) is increasingly being appreciated. Alterations in zinc dyshomeostasis has… Continue reading

Implications of Genome Wide Association Studies for Addiction: Are Our a Priori Assumptions All Wrong?

Implications of genome wide association studies for addiction: Are our a priori assumptions all wrong?

Pharmacol Ther. 2013 Jul 18;
Hall FS, Drgonova J, Jain S, Uhl GR

Substantial genetic contributions to addiction vulnerability are supported by data from… Continue reading