molecular mechanism

Transcriptome Sequencing of Gene Expression in the Brain of the HIV-1 Transgenic Rat.

Transcriptome Sequencing of Gene Expression in the Brain of the HIV-1 Transgenic Rat.

PLoS One. 2013; 8(3): e59582
Li MD, Cao J, Wang S, Wang J, Sarkar S, Vigorito M, Ma JZ, Chang SL

The noninfectious HIV-1 transgenic (HIV-1Tg)… Continue reading

Peptide Aptamers: Tools to Negatively or Positively Modulate HSPB1(27) Function.

Peptide aptamers: tools to negatively or positively modulate HSPB1(27) function.

Philos Trans R Soc Lond B Biol Sci. 2013; 368(1617): 20120075
Gibert B, Simon S, Dimitrova V, Diaz-Latoud C, Arrigo AP

Human HSP27 (HSPB1) is a molecular chaperone sensor… Continue reading

Repressive Epigenetic Changes at the Mglu2 Promoter in Frontal Cortex of 5-HT2A Knockout Mice.

Repressive Epigenetic Changes at the Mglu2 Promoter in Frontal Cortex of 5-HT2A Knockout Mice.

Mol Pharmacol. 2013 Mar 18;
Kurita M, Moreno JL, Holloway T, Kozlenkov A, Mocci G, Garcia-Bea A, Hanks JB, Neve R, Nestler EJ, Russo SJ,… Continue reading

Molecular Mechanisms of Cannabinoid Addiction.

Molecular mechanisms of cannabinoid addiction.

Curr Opin Neurobiol. 2013 Mar 12;
Fratta W, Fattore L

Cannabis is the world’s most widely used illicit substance, with an estimated number of 119-224 million users worldwide. In recent years we assisted to… Continue reading

Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations.

Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations.

J Young Pharm. 2012 10; 4(4): 199-200
Manikandan S

HubMed – drug

 

The Role of Phenethyl Isothiocyanate on Bladder Cancer ADM Resistance Reversal and Its Molecular Mechanism.

Anat Rec (Hoboken)… Continue reading

Bioequivalence Study of Pantoprazole Sodium-HPBCD and Conventional Pantoprazole Sodium Enteric-Coated Tablet Formulations.

Bioequivalence Study of Pantoprazole Sodium-HPBCD and Conventional Pantoprazole Sodium Enteric-Coated Tablet Formulations.

ISRN Pharmacol. 2013; 2013: 347457
Kamdi SP, Palkar PJ

The objective of this study was to investigate the bioequivalence of two formulations of 40?mg pantoprazole sodium enteric-coated… Continue reading

How ‘person-centered’ Care Helped Guide Me Toward Recovery From Mental Illness.

How ‘person-centered’ care helped guide me toward recovery from mental illness.

Health Aff (Millwood). 2013 Mar; 32(3): 622-6
Clayton AR

A community psychiatry researcher reflects on the treatment she received in her youth for post-traumatic stress disorder and depression-and… Continue reading

The Μ Opioid Receptor and Ligands Acting at the Μ Opioid Receptor, as Therapeutics and Potential Therapeutics.

The µ Opioid Receptor and Ligands Acting at the µ Opioid Receptor, as Therapeutics and Potential Therapeutics.

Curr Pharm Des. 2013 Feb 20;
Spetea M, Asim MF, Wolber G, Schmidhammer H

Although the µ opioid receptor (MOR) was pharmacologically… Continue reading

Gene-Environment Interactions in Major Depressive Disorder.

Gene-environment interactions in major depressive disorder.

Can J Psychiatry. 2013 Feb; 58(2): 76-83
Klengel T, Binder EB

Family, twin, and epidemiologic studies have suggested that both genes and environment are important risk factors for the development of major depressive… Continue reading

Transcriptional Mechanisms of Drug Addiction.

Transcriptional mechanisms of drug addiction.

Clin Psychopharmacol Neurosci. 2012 Dec; 10(3): 136-43
Nestler EJ

Regulation of gene expression is considered a plausible mechanism of drug addiction given the stability of behavioral abnormalities that define an addicted state. Numerous transcription… Continue reading