Molecular Imaging

Scavenger Receptor-AI-Targeted Iron Oxide Nanoparticles for in Vivo MRI Detection of Atherosclerotic Lesions.

Scavenger Receptor-AI-Targeted Iron Oxide Nanoparticles for In Vivo MRI Detection of Atherosclerotic Lesions.

Arterioscler Thromb Vasc Biol. 2013 Jun 6;
Segers FM, den Adel B, Bot I, van der Graaf LM, van der Veer E, Gonzalez W, Raynal I,… Continue reading

The Role of Tumor Tissue Architecture in Treatment Penetration and Efficacy: An Integrative Study.

The role of tumor tissue architecture in treatment penetration and efficacy: an integrative study.

Front Oncol. 2013; 3: 111
Rejniak KA, Estrella V, Chen T, Cohen AS, Lloyd MC, Morse DL

Despite the great progress that has been made… Continue reading

Proteomic Approach Toward Molecular Backgrounds of Drug Resistance of Osteosarcoma Cells in Spheroid Culture System.

Proteomic approach toward molecular backgrounds of drug resistance of osteosarcoma cells in spheroid culture system.

Proteomics. 2013 May 28;
Arai K, Sakamoto R, Kubota D, Kondo T

Chemoresistance is one of the most critical prognostic factors in osteosarcoma, and… Continue reading

Tumor Burden Talks in Cancer Treatment With PEGylated Liposomal Drugs.

Tumor Burden Talks in Cancer Treatment with PEGylated Liposomal Drugs.

PLoS One. 2013; 8(5): e63078
Lin YY, Kao HW, Li JJ, Hwang JJ, Tseng YL, Lin WJ, Lin MH, Ting G, Wang HE

PEGylated liposomes are important drug carriers that can passively target tumor by enhanced permeability and retention (EPR) effect in neoplasm lesions. This study demonstrated that tumor burden determines the tumor uptake, and also the tumor response, in cancer treatment with PEGylated liposomal drugs in a C26/tk-luc colon carcinoma-bearing mouse model.Empty PEGylated liposomes (NanoX) and those encapsulated with VNB (NanoVNB) were labeled with In-111 to obtain InNanoX and InVNBL in high labeling yield and radiochemical purity (all >90%). BALB/c mice bearing either small… Continue reading

PET Radiopharmaceuticals for Probing Enzymes in the Brain.

PET radiopharmaceuticals for probing enzymes in the brain.

Am J Nucl Med Mol Imaging. 2013; 3(3): 194-216
Holland JP, Cumming P, Vasdev N

Biologically important processes in normal brain function and brain disease involve the action of various protein-based… Continue reading

Self-Inflicted Male Bladder Foreign Body: Its Endoscopic Removal Using a Rigid Cystoscope and a Suprapubic Forceps.

Self-inflicted male bladder foreign body: its endoscopic removal using a rigid cystoscope and a suprapubic forceps.

Case Rep Urol. 2013; 2013: 729013
Moslemi MK, Sorani M

Introduction. Herein we present an interesting technique for the removal of bladder foreign… Continue reading

Synthesis and in Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging With PET.

Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging with PET.

Filed under: Drug and Alcohol Rehabilitation

ACS Chem Neurosci. 2012 Dec 19; 3(12): 1002-7
Herth MM, Volk B, Pallagi K, Kofoed Bech… Continue reading

Synthesis and in Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging With PET.

Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging with PET.

Filed under: Drug and Alcohol Rehabilitation

ACS Chem Neurosci. 2012 Dec 19; 3(12): 1002-7
Herth MM, Volk B, Pallagi K, Kofoed Bech… Continue reading

Drug and Alcohol Rehabilitation: Non-Invasive Imaging of PI3K/Akt/mTOR Signalling in Cancer.

Non-invasive imaging of PI3K/Akt/mTOR signalling in cancer.

Filed under: Drug and Alcohol Rehabilitation

Am J Nucl Med Mol Imaging. 2012; 2(4): 418-31
Gaikwad SM, Ray P

Platinum based drugs are widely used to treat various types of cancers by… Continue reading

Addiction Rehab: PET Imaging of Metabotropic Glutamate Receptor Subtype 5 (MGluR5).

PET imaging of metabotropic glutamate receptor subtype 5 (mGluR5).

Filed under: Addiction Rehab

Am J Nucl Med Mol Imaging. 2012; 2(1): 29-32
Li D, Shan H, Conti P, Li Z

Metabotropic glutamate receptors (mGluRs) belong to a family of… Continue reading