lung cancer

Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions.

Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions.

PLoS One. 2013; 8(4): e62576
D’Agnillo F, Williams MC, Moayeri M, Warfel JM

Vascular leakage pathologies such as pleural effusion and hemorrhage are hallmarks of anthrax pathogenesis. We… Continue reading

Feasibility and Effectiveness of a Home-Based Exercise Training Program Before Lung Resection Surgery.

Feasibility and effectiveness of a home-based exercise training program before lung resection surgery.

Can Respir J. 2013 Mar-Apr; 20(2): e10-6
Coats V, Maltais F, Simard S, Fréchette E, Tremblay L, Ribeiro F, Saey D

Patients with lung cancer often experience a reduction in exercise tolerance, muscle weakness and decreased quality of life. Although the effectiveness of pulmonary rehabilitation programs is well recognized in other forms of cancers and in many pulmonary diseases, few researchers have studied its impact in patients with lung cancer, particularly in those awaiting lung resection surgery (LRS).To investigate the feasibility of a short, home-based exercise training program (HBETP) with patients under investigation for non-small cell lung cancer and potential candidates for LRS, and to determine the effectiveness of this program on exercise tolerance, skeletal muscle strength and quality of life.Sixteen patients with lung cancer awaiting LRS participated in a four-week HBETP including moderate aerobic activities (walking and cycling) and muscle training performed three times weekly. Before and after the intervention, a cardiopulmonary exercise test, a 6 min walk test and the assessment of muscle strength and quality of life were performed.Thirteen patients completed the four-week HBETP and all the patients completed >75% of the prescribed exercise… Continue reading

Noninvasive Visualization of MicroRNA-16 in the Chemoresistance of Gastric Cancer Using a Dual Reporter Gene Imaging System.

Noninvasive Visualization of MicroRNA-16 in the Chemoresistance of Gastric Cancer Using a Dual Reporter Gene Imaging System.

PLoS One. 2013; 8(4): e61792
Wang F, Song X, Li X, Xin J, Wang S, Yang W, Wang J, Wu K, Chen… Continue reading

Safety and Efficacy of Pralatrexate in the Treatment of Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma.

Safety and efficacy of pralatrexate in the treatment of patients with relapsed or refractory peripheral T-cell lymphoma.

Ther Adv Hematol. 2012 Aug; 3(4): 227-35
Marchi E, O’Connor OA

T-cell lymphomas (TCL) are a diverse and heterogeneous group of malignancies… Continue reading

Nicotine and Lung Cancer.

Nicotine and lung cancer.

J Carcinog. 2013; 12: 1
Warren GW, Singh AK

Tobacco use in cancer patients is associated with increased cancer treatment failure and decreased survival. Nicotine is one of over 7,000 compounds in tobacco smoke and… Continue reading

Late-Life Depression, Mild Cognitive Impairment, and Dementia.

Late-life depression, mild cognitive impairment, and dementia.

JAMA Neurol. 2013 Mar 1; 70(3): 374-82
Richard E, Reitz C, Honig LH, Schupf N, Tang MX, Manly JJ, Mayeux R, Devanand D, Luchsinger JA

To evaluate the association of late-life depression… Continue reading

Towards Polypharmacokinetics: Pharmacokinetics of Multicomponent Drugs and Herbal Medicines Using a Metabolomics Approach.

Towards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach.

Evid Based Complement Alternat Med. 2013; 2013: 819147
Lan K, Xie G, Jia W

Determination of pharmacokinetics (PKs) of multicomponent pharmaceuticals and/or nutraceuticals (polypharmacokinetics, poly-PKs) is… Continue reading

[Analysis of Drug Therapy of Lung Cancer in Hungary].

[Analysis of drug therapy of lung cancer in Hungary].

Magy Onkol. 2013 Apr; 57(1): 33-8
Moldvay J, Rokszin G, Abonyi-Tóth Z, Katona L, Kovács G

Hungary is a world leader in the field of lung cancer deaths, so it… Continue reading

NCK2 Is Significantly Associated With Opiates Addiction in African-Origin Men.

NCK2 Is Significantly Associated with Opiates Addiction in African-Origin Men.

ScientificWorldJournal. 2013; 2013: 748979
Liu Z, Guo X, Jiang Y, Zhang H

Substance dependence is a complex environmental and genetic disorder with significant social and medical concerns. Understanding the… Continue reading

Reduced Susceptibility of Plasmodium Falciparum to Artesunate in Southern Myanmar.

Reduced Susceptibility of Plasmodium falciparum to Artesunate in Southern Myanmar.

PLoS One. 2013; 8(3): e57689
Kyaw MP, Nyunt MH, Chit K, Aye MM, Aye KH, Aye MM, Lindegardh N, Tarning J, Imwong M, Jacob CG, Rasmussen C, Perin J,… Continue reading