long-term potentiation

SAHA Enhances Synaptic Function and Plasticity in Vitro but Has Limited Brain Availability in Vivo and Does Not Impact Cognition.

Published August 9, 2013

... and memory, raising the possibility that SAHA treatment could have neurological benefits. We first examined the impacts of SAHA on synaptic function in vitro using rat organotypic hippocampal brain slices. Following several days of SAHA treatment, basal excitatory but… Continue reading →

Emergence of GABAergic-Dependent Regulation of Input-Specific Plasticity in the Adult Rat Prefrontal Cortex During Adolescence.

Published August 4, 2013

... on PFC plasticity.Ventral hippocampal-induced PFC plasticity begins to appear only by postnatal days (P) 45-55 with a transient suppression of the evoked response. A switch from transient to long-lasting depression (LTD) of the PFC response emerges after P55 and… Continue reading →

Lipocalin-2 Is Involved in Emotional Behaviors and Cognitive Function.

Published August 4, 2013

... alterations were associated with a hyperactivation of the hypothalamic-pituitary-adrenal axis and with an altered brain cytoarchitecture in the hippocampus. More specifically, we found that the granular and pyramidal neurons of the ventral hippocampus, a region described to be associated… Continue reading →

A Nine-Year Follow-Up Study of Sleep Patterns and Mortality in Community-Dwelling Older Adults in Taiwan.

Published August 2, 2013

... of function on par with younger adults. Research on the neural basis for age-related memory decline has focused primarily on the CA1 region of the hippocampus. However, recent studies in elderly human and rodents indicate that individual differences in… Continue reading →

Neurobiological Effects of the Green Tea Constituent Theanine and Its Potential Role in the Treatment of Psychiatric and Neurodegenerative Disorders.

Published July 27, 2013

... possible modulation of serotonin and dopamine in selected areas. It has also recently been shown to increase levels of brain-derived neurotrophic factor. An increasing number of studies demonstrate a neuroprotective effects following cerebral infarct and injury, although the exact… Continue reading →

Activation of CRH Receptor Type 1 Expressed on Glutamatergic Neurons Increases Excitability of CA1 Pyramidal Neurons by the Modulation of Voltage-Gated Ion Channels.

Published July 26, 2013

... understood. The effects of CRH on neuronal excitability were investigated in acute hippocampal brain slices. Population spikes (PS) and field excitatory postsynaptic potentials (fEPSP) were evoked by stimulating Schaffer-collaterals and recorded simultaneously from the somatic and dendritic region of… Continue reading →

Cortical Shape and Curvedness Analysis of Structural Deficits in Remitting and Non-Remitting Depression.

Published July 24, 2013

... preferential utilization of serotonin for production of melatonin and 5-MTPOL. HubMed – depression Decoding the substrate supply to human neuronal nitric oxide synthase. PLoS One. 2013; 8(7): e67707Simon A, Karbach S, Habermeier A, Closs EI Nitric oxide, produced by… Continue reading →

Cardiovascular Profile of Xanthelasma Palpebrarum.

Published July 19, 2013

... Synapses Encodes Motivation to Self-Administer Cocaine in Rats. J Neurosci. 2013 Jul 17; 33(29): 11960-11971Krawczyk M, Mason X, Debacker J, Sharma R, Normandeau CP, Hawken ER, Di Prospero C, Chiang C, Martinez A, Jones AA, Doudnikoff E, Caille S,… Continue reading →

The Effect of Acute Swim Stress and Training in the Water Maze on Hippocampal Synaptic Activity as Well as Plasticity in the Dentate Gyrus of Freely Moving Rats: Revisiting Swim-Induced LTP Reinforcement.

Published July 10, 2013

... effect of acute swim stress and training in the water maze on hippocampal synaptic activity as well as plasticity in the dentate gyrus of freely moving rats: Revisiting swim-induced LTP reinforcement. Hippocampus. 2013 Jul 8; Tabassum H, Frey JU… Continue reading →

Development of a Positive Psychology Intervention for Patients With Acute Cardiovascular Disease.

Published July 5, 2013

... role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling. J Neurosci. 2013 Jul 3; 33(27): 11206-11Siddoway BA, Altimimi HF, Hou H, Petralia RS, Xu B, Stellwagen D, Xia H Protein phosphatase-1 (PP1) activity is important for many calcium-dependent… Continue reading →