liquid chromatography

Association Between Ward-Specific Antimicrobial Use Density and Methicillin-Resistant Staphylococcu Aureus Surveillance: A 60-Month Study.

Association between ward-specific antimicrobial use density and methicillin-resistant Staphylococcu aureus surveillance: a 60-month study.

Infect Drug Resist. 2013; 6: 59-66
Yoshida J, Kikuchi T, Matsubara N, Asano I, Ogami N

It is not known whether or not ward-specific antimicrobial… Continue reading

The Pharmacists’ Potential to Provide Targets for Interventions to Optimize Pharmacotherapy in Patients With Asthma.

The pharmacists’ potential to provide targets for interventions to optimize pharmacotherapy in patients with asthma.

Int J Clin Pharm. 2013 Jul 26;
van Boven JF, Hiddink EG, Stuurman-Bieze AG, Schuiling-Veninga CC, Postma MJ, Vegter S

Background Despite of pharmacists’ specialized knowledge of medication and his/her regular contact with patients, the expertise of the pharmacist may not be used enough yet. Furthermore, the potential of pharmacy dispensing data is underestimated. Objective To provide targets for tailored interventions in asthma patients and to illustrate the potential value of pharmacists in the identification of these targets using individual pharmacy dispensing data. Setting We performed a cross sectional retrospective analysis assessing the quality of asthma patients’ pharmacotherapeutic treatment. Method Drug dispensing data from 2008 to 2009 were retrieved from a Dutch pharmacy database. All asthma patients were screened for potential suboptimal pharmacotherapy in 2009. Results were projected to a single community pharmacy to provide an estimate of the number of patients eligible for potential interventions. Main outcome measures (1) frequent use of short-acting ?-agonists without preventive medication, (2) concomitant use of ?-blockers, (3) multiple short courses of oral corticosteroids without using inhaled corticosteroids and 4) use of long-acting ?-agonist without inhaled corticosteroids. Results A total of 8,504 patients were eligible for analysis of the quality of their asthma treatment. 20.9 % of all asthma patients used >100 DDD short-acting ?-agonists… Continue reading

Role of Benzodiazepines in the Management of Agitation Due to Inappropriate Use of Naltrexone.

Role of Benzodiazepines in the management of agitation due to inappropriate use of naltrexone.

Iran J Nurs Midwifery Res. 2012 7; 17(5): 365-369
Sabzghabaee AM, Eizadi-Mood N, Gheshlaghi F, Javani A, Shirani S, Aghaabdollahian S

Agitation is an early… Continue reading

Cross-Reactivities and Structure-Reactivity Relationships of Six Benzodiazepines to EMIT(®) Immunoassay.

Cross-reactivities and structure-reactivity relationships of six benzodiazepines to EMIT(®) immunoassay.

J Pharm Biomed Anal. 2013 Jun 10; 84C: 168-172
Bertol E, Vaiano F, Furlanetto S, Mari F

Benzodiazepines are among the most frequently prescribed drugs due to their sedative,… Continue reading

Identification of (2-Aminopropyl)indole Positional Isomers in Forensic Samples.

Identification of (2-aminopropyl)indole positional isomers in forensic samples.

Drug Test Anal. 2013 Jul 8;
Scott KR, Power JD, McDermott SD, O’Brien JE, Talbot BN, Barry MG, Kavanagh PV

In 2012, 5-(2-aminopropyl)indole (5-API, 5-IT) was reported by Norwegian authorities to… Continue reading

Preventive Effects of Curcumin Against Drug- and Starvation-Induced Gastric Erosions in Rats.

Preventive effects of curcumin against drug- and starvation-induced gastric erosions in rats.

Sci Pharm. 2013 Jun; 81(2): 549-58
Haider S, Naqvi F, Tabassum S, Saleem S, Batool Z, Sadir S, Rasheed S, Saleem D, Nawaz A, Ahmad S

The… Continue reading

In Silico and in Vitro Metabolism Studies Support Identification of Designer Drugs in Human Urine by Liquid Chromatography/quadrupole-Time-of-Flight Mass Spectrometry.

In silico and in vitro metabolism studies support identification of designer drugs in human urine by liquid chromatography/quadrupole-time-of-flight mass spectrometry.

Anal Bioanal Chem. 2013 Jun 25;
Tyrkkö E, Pelander A, Ketola RA, Ojanperä I

Human phase I metabolism of… Continue reading

?4?6?2* nAChR Activation on VTA DA Neurons Is Sufficient to Stimulate a Depolarizing Conductance and Enhance Surface AMPA Receptor Function.

?4?6?2* nAChR Activation on VTA DA Neurons is Sufficient to Stimulate a Depolarizing Conductance and Enhance Surface AMPA Receptor Function.

Mol Pharmacol. 2013 Jun 20;
Engle SE, Shih PY, McIntosh JM, Drenan RM

Tobacco addiction is a serious threat… Continue reading

Optimization and Validation of Spectrophotometric Methods for Determination of Finasteride in Dosage and Biological Forms.

Optimization and validation of spectrophotometric methods for determination of finasteride in dosage and biological forms.

Pharm Methods. 2012 Jan; 3(1): 48-55
Amin AS, Kassem MA

Three simple, accurate and sensitive spectrophotometric methods for the determination of finasteride in pure,… Continue reading

Development and Validation of a Stability Indicating RP-HPLC Method for Simultaneous Estimation of Olmesartan Medoxomil and Metoprolol Succinate in Pharmaceutical Dosage Form.

Development and validation of a stability indicating RP-HPLC method for simultaneous estimation of Olmesartan Medoxomil and Metoprolol Succinate in pharmaceutical dosage form.

Pharm Methods. 2012 Jul; 3(2): 84-9
Thakker NM, Panchal HB, Rakholiya DR, Murugan R, Choudhari VP, Kuchekar… Continue reading