Evaluation of the EndoPAT as a Tool to Assess Endothelial Function.

Filed under: Drug and Alcohol Rehabilitation

Int J Vasc Med. 2012; 2012: 904141
Moerland M, Kales AJ, Schrier L, van Dongen MG, Bradnock D, Burggraaf J

Endothelial dysfunction is a potential target for (pharmaceutical) intervention of several systemic pathological conditions. We investigated the feasibility of the EndoPAT to evaluate acute changes in endothelial function with repeated noninvasive measurements and assessed its discriminating power in different populations. Endothelial function was stable over a longer period of time in renally impaired patients (coefficient of variation 13%). Endothelial function in renally impaired and type 2 diabetic patients was not decreased compared to healthy volunteers (2.9 ± 1.4 and 1.8 ± 0.3, resp., versus 1.8 ± 0.5, P > 0.05). The… Continue reading →