drug design

Poisoning With Depilatory Agents in Iran.

Poisoning with depilatory agents in Iran.

J Res Med Sci. 2013 Feb; 18(2): 168-9
Mehrpour O, Farzaneh E, Hasanian-Moghaddam H, Abdollahi A, Rayesson MR, Abdollahi M

HubMed – addiction

Addiction is a Reward Deficit and Stress Surfeit Disorder.

Front… Continue reading

Adherence to Treatment With Imatinib in Chronic Myeloid Leukemia: A Study of the First Decade of Responses Obtained at a Brazilian Hospital.

Adherence to treatment with imatinib in chronic myeloid leukemia: a study of the first decade of responses obtained at a Brazilian hospital.

Rev Bras Hematol Hemoter. 2013; 35(3): 174-9
Dos Reis SR, Quixadá AT, Nunes ST, Cid DM, de… Continue reading

The Pharmacists’ Potential to Provide Targets for Interventions to Optimize Pharmacotherapy in Patients With Asthma.

The pharmacists’ potential to provide targets for interventions to optimize pharmacotherapy in patients with asthma.

Int J Clin Pharm. 2013 Jul 26;
van Boven JF, Hiddink EG, Stuurman-Bieze AG, Schuiling-Veninga CC, Postma MJ, Vegter S

Background Despite of pharmacists’ specialized knowledge of medication and his/her regular contact with patients, the expertise of the pharmacist may not be used enough yet. Furthermore, the potential of pharmacy dispensing data is underestimated. Objective To provide targets for tailored interventions in asthma patients and to illustrate the potential value of pharmacists in the identification of these targets using individual pharmacy dispensing data. Setting We performed a cross sectional retrospective analysis assessing the quality of asthma patients’ pharmacotherapeutic treatment. Method Drug dispensing data from 2008 to 2009 were retrieved from a Dutch pharmacy database. All asthma patients were screened for potential suboptimal pharmacotherapy in 2009. Results were projected to a single community pharmacy to provide an estimate of the number of patients eligible for potential interventions. Main outcome measures (1) frequent use of short-acting ?-agonists without preventive medication, (2) concomitant use of ?-blockers, (3) multiple short courses of oral corticosteroids without using inhaled corticosteroids and 4) use of long-acting ?-agonist without inhaled corticosteroids. Results A total of 8,504 patients were eligible for analysis of the quality of their asthma treatment. 20.9 % of all asthma patients used >100 DDD short-acting ?-agonists… Continue reading

Clinical Approach to Fever in the Neurosurgical Intensive Care Unit: Focus on Drug Fever.

Clinical approach to fever in the neurosurgical intensive care unit: Focus on drug fever.

Surg Neurol Int. 2013; 4(Suppl 5): S318-22
Cunha BA

As fever is one of the cardinal signs of infection, the presence of fever in a patient in the neurosurgical intensive care unit (NSICU) raises the question of whether it is infectious in etiology. Infectious and noninfectious causes of fever in the NSICU may be determined based upon assessment of clinical signs and symptoms, the degree of temperature elevation, the relationship of the pulse to the fever (e.g., an infectious process resulting in hyperpyrexia and bradycardia), and when the fever occurs (e.g., related to the length of stay in the NSICU). There are many noninfectious disorders which contribute to temperatures >102°F in the NSICU; these include drug fevers, deep vein thrombosis, phlebitis/pulmonary embolism, acute myocardial infarction, atelectasis, dehydration, acute gout flare, malignancy, acute pancreatitis, transfusion associated hepatitis, and hemorrhage. Infectious rather than noninfectious disorders, however, are more typically associated with high-grade fevers (>102°F.) in the NSICU, and nosocomial pneumonia, (synonymous with ventilator-associated pneumonia [VAP]), is the leading culprit,… Continue reading

Warning Signs of Adolescent Depression – Voice Article


 

Warning Signs Of Adolescent Depression – Voice Article – Warning Signs Of Adolescent Depression We are all concerned about the health of our children from the moment that they emerge into the world, but an overlook…

 

Don't abort… Continue reading

Reconciling Parenting and Smoking in the Context of Child Development.

Reconciling Parenting and Smoking in the Context of Child Development.

Qual Health Res. 2013 Jun 17;
Bottorff JL, Oliffe JL, Kelly MT, Johnson JL, Chan A

In this article we explore the micro-social context of parental tobacco use in… Continue reading

Comparative Proteomic Analysis of Peritoneal Dialysate From Chronic Glomerulonephritis Patients.

Comparative proteomic analysis of peritoneal dialysate from chronic glomerulonephritis patients.

Biomed Res Int. 2013; 2013: 863860
Wu HY, Liao AC, Huang CC, Liao PC, Chien CC, Kan WC, Wang HY

Peritoneal dialysis (PD) frequently contributes to peritoneal damage which… Continue reading

Protein-Protein Interactions Inferred From Domain-Domain Interactions in Genogroup II Genotype 4 Norovirus Sequences.

Protein-Protein Interactions Inferred from Domain-Domain Interactions in Genogroup II Genotype 4 Norovirus Sequences.

Int J Genomics. 2013; 2013: 456356
Huang CC, Tang CY

Severe gastroenteritis and foodborne illness caused by Noroviruses (NoVs) during the winter are a worldwide phenomenon.… Continue reading

BcL-xL Conformational Changes Upon Fragment Binding Revealed by NMR.

BcL-xL Conformational Changes upon Fragment Binding Revealed by NMR.

PLoS One. 2013; 8(5): e64400
Aguirre C, Ten Brink T, Walker O, Guillière F, Davesne D, Krimm I

Protein-protein interactions represent difficult but increasingly important targets for the design of… Continue reading

Induction Chemotherapy in Technically Unresectable Locally Advanced Oral Cavity Cancers: Does It Make a Difference?

Induction chemotherapy in technically unresectable locally advanced oral cavity cancers: Does it make a difference?

Indian J Cancer. 2013 Jan-Mar; 50(1): 1-8
Patil VM, Noronha V, Muddu VK, Gulia S, Bhosale B, Arya S, Juvekar S, Chatturvedi P, Chaukar… Continue reading