Crohn’s disease

Effect of DA-9701 on Gastric Emptying in a Mouse Model: Assessment by (13)C-Octanoic Acid Breath Test.

Effect of DA-9701 on gastric emptying in a mouse model: Assessment by (13)C-octanoic acid breath test.

World J Gastroenterol. 2013 Jul 21; 19(27): 4380-5
Lim CH, Choi MG, Park H, Baeg MK, Park JM

To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the (13)C-octanoic acid breath test in a mouse model.Male C57BL/6 mice aged > 8 wk and with body… Continue reading

IL-23R Is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer.

IL-23R is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer.

Front Oncol. 2013; 3: 162
Baird AM, Dockry E, Daly A, Stack E, Doherty DG, O’Byrne KJ, Gray SG

The Interleukin-23 (IL-23)/IL-23R signaling axis is an… Continue reading

Optimization of Drug Delivery Systems for Intraperitoneal Therapy to Extend the Residence Time of the Chemotherapeutic Agent.

Optimization of drug delivery systems for intraperitoneal therapy to extend the residence time of the chemotherapeutic agent.

ScientificWorldJournal. 2013; 2013: 720858
De Smet L, Ceelen W, Remon JP, Vervaet C

Intraperitoneal (IP) chemotherapy is an effective way of treating… Continue reading

Depressive Symptoms in Crohn’s Disease: Relationship With Immune Activation and Tryptophan Availability.

Depressive symptoms in Crohn’s disease: relationship with immune activation and tryptophan availability.

PLoS One. 2013; 8(3): e60435
Guloksuz S, Wichers M, Kenis G, Russel MG, Wauters A, Verkerk R, Arts B, van Os J

Crohn’s disease (CD) is associated… Continue reading

Dysregulation of Synaptic Plasticity Precedes Appearance of Morphological Defects in a Pten Conditional Knockout Mouse Model of Autism.

Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.

Proc Natl Acad Sci U S A. 2013 Mar 4;
Takeuchi K, Gertner MJ, Zhou J, Parada LF, Bennett MV, Zukin… Continue reading

Gene Expression and Thiopurine Metabolite Profiling in Inflammatory Bowel Disease – Novel Clues to Drug Targets and Disease Mechanisms?

Gene expression and thiopurine metabolite profiling in inflammatory bowel disease – novel clues to drug targets and disease mechanisms?

PLoS One. 2013; 8(2): e56989
Haglund S, Almer S, Peterson C, Söderman J

Thiopurines are effective to induce and maintain remission in inflammatory bowel disease (IBD). The methyl thioinosine monophosphate (meTIMP)/6-thioguanine nucleotide (6-TGN) concentration ratio has been associated with drug efficacy. Here we explored the molecular basis of differences in metabolite profiles and in relation to disease activity.Transcriptional profiles in blood samples from an exploratory IBD-patient cohort (n?=?21) with a normal thiopurine S-methyltransferase phenotype and meTIMP/6-TGN ratios >20, 10.0-14.0 and ?4, respectively, were assessed… Continue reading

Sick and Tired of Being Sick and Tired


 

Sick And Tired Of Being Sick And Tired – WPBF News 25’s Terri Parker takes a look at the problem some women are having while trying to find a diagnosis to their health problems.

 

What's Going Around: Seasonal… Continue reading

Sex-Dimorphic Adverse Drug Reactions to Immune Suppressive Agents in Inflammatory Bowel Disease.

Sex-dimorphic adverse drug reactions to immune suppressive agents in inflammatory bowel disease.

Filed under: Drug and Alcohol Rehabilitation

World J Gastroenterol. 2012 Dec 21; 18(47): 6967-73
Zelinkova Z, Bultman E, Vogelaar L, Bouziane C, Kuipers EJ, van der Woude… Continue reading

Acquired Zinc Deficiency in an Adult Female.

Acquired zinc deficiency in an adult female.

Filed under: Eating Disorders

Indian J Dermatol. 2012 Nov; 57(6): 492-4
Saritha M, Gupta D, Chandrashekar L, Thappa DM, Rajesh NG

Acrodermatitis enteropathica is an autosomal recessive inherited disorder of zinc absorption.… Continue reading

Eating Disorders: Clinical Diagnostic Clues in Crohn’s Disease: A 41-Year Experience.

Clinical diagnostic clues in Crohn’s disease: a 41-year experience.

Filed under: Eating Disorders

ISRN Gastroenterol. 2012; 2012: 285475
Quintana C, Galleguillos L, Benavides E, Quintana JC, Zúñiga A, Duarte I, Klaassen J, Kolbach M, Soto RM, Iacobelli S, Alvarez… Continue reading