controlled clinical trial

Do Hormone Treatments for Prostate Cancer Cause Anxiety and Depression?

Do hormone treatments for prostate cancer cause anxiety and depression?

Int J Clin Oncol. 2013 Jun 1;
Sharpley CF, Christie DR, Bitsika V

BACKGROUND: To investigate the relationship between hormone therapy (HT) and incidence of anxiety and depression among… Continue reading

Atypical Antipsychotic Augmentation Strategies in the Context of Guideline-Based Care for the Treatment of Major Depressive Disorder.

Atypical Antipsychotic Augmentation Strategies in the Context of Guideline-based Care for the Treatment of Major Depressive Disorder.

CNS Drugs. 2013 May 25;
Patkar AA, Pae CU

There is a growing body of evidence that supports the use of atypical… Continue reading

Correlation of Angiogenic Biomarker Signatures With Clinical Outcomes in Metastatic Colorectal Cancer Patients Receiving Capecitabine, Oxaliplatin, and Bevacizumab.

Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab.

Cancer Med. 2013 Apr; 2(2): 234-42
Liu Y, Starr MD, Bulusu A, Pang H, Wong NS, Honeycutt W, Amara A, Hurwitz… Continue reading

Can MDMA Play a Role in the Treatment of Substance Abuse?

Can MDMA Play a Role in the Treatment of Substance Abuse?

Curr Drug Abuse Rev. 2013 Apr 29;
Jerome L, Shira Schuster MA, Yazar-Klosinski BB

A wider array of treatments are needed for people with substance abuse disorders. Some… Continue reading

The Effect of 2 Different Single Injections of High Dose of Vitamin D on Improving the Depression in Depressed Patients With Vitamin D Deficiency: A Randomized Clinical Trial.

The Effect of 2 Different Single Injections of High Dose of Vitamin D on Improving the Depression in Depressed Patients With Vitamin D Deficiency: A Randomized Clinical Trial.

J Clin Psychopharmacol. 2013 Apr 19;
Mozaffari-Khosravi H, Nabizade L, Yassini-Ardakani… Continue reading

Acute Hamstring Injuries in Swedish Elite Football: A Prospective Randomised Controlled Clinical Trial Comparing Two Rehabilitation Protocols.

Acute hamstring injuries in Swedish elite football: a prospective randomised controlled clinical trial comparing two rehabilitation protocols.

Br J Sports Med. 2013 Mar 27;
Askling CM, Tengvar M, Thorstensson A

BACKGROUND: Hamstring injury is the single most common injury… Continue reading

Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice.

Scientific challenges and implementation barriers to translation of pharmacogenomics in clinical practice.

ISRN Pharmacol. 2013; 2013: 641089
Lam YW

The mapping of the human genome and subsequent advancements in genetic technology had provided clinicians and scientists an understanding of… Continue reading

Oral Rehabilitation of an Edentulous Patient Using Two-Segment Le Fort I Repositioning and Implant-Supported Fixed Prostheses.

Oral rehabilitation of an edentulous patient using two-segment le fort I repositioning and implant-supported fixed prostheses.

Int J Oral Maxillofac Implants. 2013 Mar-Apr; 28(2): e106-11
Abdel-Azim T, Fantuzzo J, Batalocco G, Cho S, Ercoli C, Morton D

Anteroposterior (AP)… Continue reading

Post Laryngectomy Speech Rehabilitation Outcome in Elderly Patients.

Post laryngectomy speech rehabilitation outcome in elderly patients.

Eur Arch Otorhinolaryngol. 2013 Mar 22;
Cocuzza S, Bonfiglio M, Grillo C, Maiolino L, Malaguarnera M, Martines F, Serra A

The aim of our work has been to evaluate the different options of tracheoesophageal voice rehabilitation in over 70-year-old patients, who had undergone laryngectomy, assessing advantages and drawbacks of this method of vocal recovery. A retrospective study has been carried out. This has included 40 subjects, all aged more than 70 years old, who have been referred to tracheoesophageal voice rehabilitation. It has been realized a phonatory fistula between trachea and esophagus with prosthesis positioning by means of a primary puncture in 18 cases and it has been realized a secondary puncture in 22 cases. The results gathered in these patients were compared with data obtained from a group made of 39 patients, less than 70 years of age that therefore represented our control group. In primary tracheoesophageal puncture (TEP), the short-term success was 67 %, while in the 22 cases who underwent secondary TEP, the short-term success was 64 %. After 2 years from TEP, the long-term success was 82.5 %. In the control group, the short-term success was 65 % in primary TEP and 73 % in secondary TEP. After 2 years from TEP, the long-term success was 77 %. The evaluation of the results has shown the absence of a statistically significant difference both as regards complications incidence, during and after surgery (p > 0.9) and as regards overall success ratio of prosthesis implants between the two groups (p > 0.7). The possibilities of tracheoesophageal recovery of elderly patients do… Continue reading

Molecular Mechanisms of Cannabinoid Addiction.

Molecular mechanisms of cannabinoid addiction.

Curr Opin Neurobiol. 2013 Mar 12;
Fratta W, Fattore L

Cannabis is the world’s most widely used illicit substance, with an estimated number of 119-224 million users worldwide. In recent years we assisted to… Continue reading