clinical trials

Human Experimental Pain Models: A Review of Standardized Methods in Drug Development.

Human experimental pain models: A review of standardized methods in drug development.

J Res Med Sci. 2012 Jun; 17(6): 587-95
Reddy KS, Naidu MU, Rani PU, Rao TR

Human experimental pain models are essential in understanding the pain mechanisms… Continue reading

Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions.

Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions.

PLoS One. 2013; 8(4): e62576
D’Agnillo F, Williams MC, Moayeri M, Warfel JM

Vascular leakage pathologies such as pleural effusion and hemorrhage are hallmarks of anthrax pathogenesis. We… Continue reading

Chlamydophila Pneumoniae Infection and Cardiovascular Disease.

Chlamydophila pneumoniae infection and cardiovascular disease.

N Am J Med Sci. 2013 Mar; 5(3): 169-81
Joshi R, Khandelwal B, Joshi D, Gupta OP

Atherosclerosis is a multifactorial vascular inflammatory process; however, the inciting cause for inflammation remains unclear. Two… Continue reading

Antiaggressive Activity of Central Oxytocin in Male Rats.

Antiaggressive activity of central oxytocin in male rats.

Psychopharmacology (Berl). 2013 Apr 28;
Calcagnoli F, de Boer SF, Althaus M, den Boer JA, Koolhaas JM

RATIONALE: A substantial body of research suggests that the neuropeptide oxytocin promotes social affiliative… Continue reading

Evaluation of Digoxin Concentration After Loading Dose in Patients With Renal Dysfunction.

Evaluation of digoxin concentration after loading dose in patients with renal dysfunction.

Can J Hosp Pharm. 2013 Mar; 66(2): 104-9
Pawlosky N, Macdonald E, Patel R, Kanji S

Loading dose recommendations for digoxin are based on the volume of… Continue reading

A Model of Postsurgical Advanced Metastatic Breast Cancer More Accurately Replicates the Clinical Efficacy of Antiangiogenic Drugs.

A Model of Postsurgical Advanced Metastatic Breast Cancer More Accurately Replicates the Clinical Efficacy of Antiangiogenic Drugs.

Cancer Res. 2013 Apr 22;
Guerin E, Man S, Xu P, Kerbel RS

The failure rate of randomized phase III oncology clinical… Continue reading

Safety and Efficacy of Deferasirox in the Management of Transfusion-Dependent Patients With Myelodysplastic Syndrome and Aplastic Anaemia: A Perspective Review.

Safety and efficacy of deferasirox in the management of transfusion-dependent patients with myelodysplastic syndrome and aplastic anaemia: a perspective review.

Ther Adv Hematol. 2013 Apr; 4(2): 93-102
Adams RL, Bird RJ

Deferasirox is an orally administered, once-daily iron chelator… Continue reading

Safety and Efficacy of Pralatrexate in the Treatment of Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma.

Safety and efficacy of pralatrexate in the treatment of patients with relapsed or refractory peripheral T-cell lymphoma.

Ther Adv Hematol. 2012 Aug; 3(4): 227-35
Marchi E, O’Connor OA

T-cell lymphomas (TCL) are a diverse and heterogeneous group of malignancies… Continue reading

Successful Use of Cyclophosphamide as an Add-on Therapy for Multiple Myeloma Patients With Acquired Resistance to Bortezomib or Lenalidomide.

Successful use of cyclophosphamide as an add-on therapy for multiple myeloma patients with acquired resistance to bortezomib or lenalidomide.

Case Rep Hematol. 2013; 2013: 651902
Ito S, Oyake T, Murai K, Ishida Y

Novel agents such as thalidomide, lenalidomide,… Continue reading

Ben Stasiewicz – Through Depression and Beyond


 

Ben Stasiewicz – Through Depression and Beyond – Ben Stasiewicz from Wellignton shares the story of his own journey through depression, how he came to personally know Jesus Christ, and what difference that …

 

There's a pill for… Continue reading