clinical studies

Use of Bayesian Statistics in Drug Development: Advantages and Challenges.

Use of Bayesian statistics in drug development: Advantages and challenges.

Int J Appl Basic Med Res. 2012 Jan; 2(1): 3-6
Gupta SK

MAINLY, TWO STATISTICAL METHODOLOGIES ARE APPLICABLE TO THE DESIGN AND ANALYSIS OF CLINICAL TRIALS: frequentist and Bayesian.… Continue reading

Rapid Buildup of Brain White Matter Hyperintensities Over 4 Years Linked to Ambulatory Blood Pressure, Mobility, Cognition, and Depression in Old Persons.

Rapid Buildup of Brain White Matter Hyperintensities Over 4 Years Linked to Ambulatory Blood Pressure, Mobility, Cognition, and Depression in Old Persons.

J Gerontol A Biol Sci Med Sci. 2013 Jun 13;
Wolfson L, Wakefield DB, Moscufo N, Kaplan… Continue reading

Is Weight-Bearing Asymmetry Associated With Postural Instability After Stroke? a Systematic Review.

Is weight-bearing asymmetry associated with postural instability after stroke? A systematic review.

Stroke Res Treat. 2013; 2013: 692137
Kamphuis JF, de Kam D, Geurts AC, Weerdesteyn V

Introduction. Improvement of postural stability is an important goal during poststroke rehabilitation.… Continue reading

Protein-Protein Interactions Inferred From Domain-Domain Interactions in Genogroup II Genotype 4 Norovirus Sequences.

Protein-Protein Interactions Inferred from Domain-Domain Interactions in Genogroup II Genotype 4 Norovirus Sequences.

Int J Genomics. 2013; 2013: 456356
Huang CC, Tang CY

Severe gastroenteritis and foodborne illness caused by Noroviruses (NoVs) during the winter are a worldwide phenomenon.… Continue reading

US Approves “New Class” of Diabetes Drug, Under Review in Canada.

US approves “new class” of diabetes drug, under review in Canada.

CMAJ. 2013 Jun 3;
Lange-Chenier H

HubMed – drug

 

Medicare Covers The Majority Of FDA-Approved Devices And Part B Drugs, But Restrictions And Discrepancies Remain.

Health Aff… Continue reading

Environmental Enrichment Effects on the Neurobehavioral Profile of Selective Outbred Trait Anxiety Rats.

Environmental enrichment effects on the neurobehavioral profile of selective outbred trait anxiety rats.

Behav Brain Res. 2013 May 29;
Ravenelle R, Byrnes EM, Byrnes JJ, McInnis C, Park JH, Donaldson ST

Environmental enrichment attenuates the response to psychostimulants and… Continue reading

What Do You Think of the Book “the Antidepressant Survival Program” by Hedaya?

Question by vivaldi558: What do you think of the book “The Antidepressant Survival Program” by Hedaya?
What I am seeking to find out is whether you experts out there think that Dr. Hedaya is way out in left field or… Continue reading

Avoiding Anti-Depressants for Bipolar Depression


 

Avoiding Anti-Depressants For Bipolar Depression

 

Living With Depression by Deborah Serani
There several kinds of bipolar disorders. Bipolar I disorder is the most serious of the bipolar disorders and is diagnosed after at least one episode of… Continue reading

What Is the Role of Brain Stimulation Therapies in the Treatment of Depression?

What Is the Role of Brain Stimulation Therapies in the Treatment of Depression?

Curr Psychiatry Rep. 2013 Jul; 15(7): 368
Blumberger DM, Mulsant BH, Daskalakis ZJ

Brain stimulation therapies have demonstrated efficacy in the treatment of depression and treatment-resistant… Continue reading

Atypical Antipsychotic Augmentation Strategies in the Context of Guideline-Based Care for the Treatment of Major Depressive Disorder.

Atypical Antipsychotic Augmentation Strategies in the Context of Guideline-based Care for the Treatment of Major Depressive Disorder.

CNS Drugs. 2013 May 25;
Patkar AA, Pae CU

There is a growing body of evidence that supports the use of atypical… Continue reading