clinical studies

Potential Use of Custirsen to Treat Prostate Cancer.

Potential use of custirsen to treat prostate cancer.

Onco Targets Ther. 2013; 6: 785-97
Higano CS

Over the last few years, five agents have demonstrated a survival benefit over a comparator treatment or placebo in the treatment of metastatic… Continue reading

Neurophysiological Signals as Potential Translatable Biomarkers for Modulation of Metabotropic Glutamate 5 Receptors.

Neurophysiological signals as potential translatable biomarkers for modulation of metabotropic glutamate 5 receptors.

Neuropharmacology. 2013 Jul 4;
Harvey BD, Siok CJ, Kiss T, Volfson D, Grimwood S, Shaffer CL, Hajós M

The Group I metabotropic glutamate receptor subtype 5… Continue reading

Preventive Effects of Curcumin Against Drug- and Starvation-Induced Gastric Erosions in Rats.

Preventive effects of curcumin against drug- and starvation-induced gastric erosions in rats.

Sci Pharm. 2013 Jun; 81(2): 549-58
Haider S, Naqvi F, Tabassum S, Saleem S, Batool Z, Sadir S, Rasheed S, Saleem D, Nawaz A, Ahmad S

The… Continue reading

Images in Electroconvulsive Therapy: Pilot Impressions Suggesting That ECT Reduces Excitatory Synapses in the Basolateral Amygdala.

Images in electroconvulsive therapy: Pilot impressions suggesting that ECT reduces excitatory synapses in the basolateral amygdala.

Indian J Psychiatry. 2013 Apr; 55(2): 204-5
Khaleel N, Ravindranath R, Sagar BK, Andrade C

In animal models, stress and depression are associated… Continue reading

Neurotoxic Saboteurs: Straws That Break the Hippo’s (Hippocampus) Back Drive Cognitive Impairment and Alzheimer’s Disease.

Neurotoxic Saboteurs: Straws that Break the Hippo’s (Hippocampus) Back Drive Cognitive Impairment and Alzheimer’s Disease.

Neurotox Res. 2013 Jul 3;
Daulatzai MA

Late onset Alzheimer’s disease (AD) is the most common cause of progressive cognitive dysfunction and dementia. Despite… Continue reading

Differential Roles of the Prefrontal Cortical Subregions and Basolateral Amygdala in Compulsive Cocaine Seeking and Relapse After Voluntary Abstinence in Rats.

Differential roles of the prefrontal cortical subregions and basolateral amygdala in compulsive cocaine seeking and relapse after voluntary abstinence in rats.

Eur J Neurosci. 2013 Jul 1;
Pelloux Y, Murray JE, Everitt BJ

Compulsive drug use and a persistent… Continue reading

Beneficial Effects of Omega-3 Fatty Acids on Low Density Lipoprotein Particle Size in Patients With Type 2 Diabetes Already Under Statin Therapy.

Beneficial Effects of Omega-3 Fatty Acids on Low Density Lipoprotein Particle Size in Patients with Type 2 Diabetes Already under Statin Therapy.

Diabetes Metab J. 2013 Jun; 37(3): 207-211
Lee MW, Park JK, Hong JW, Kim KJ, Shin DY,… Continue reading

Managing Hepatitis C in Users of Illicit Drugs.

Managing Hepatitis C in Users of Illicit Drugs.

Curr Hepat Rep. 2007; 6(2): 60-67
Edlin BR, Carden MR, Ferrando SJ

Persons who inject illicit drugs are the group most severely affected by the hepatitis C epidemic but the least… Continue reading

The Context Dependency of Extinction Negates the Effectiveness of Cognitive Enhancement to Reduce Cocaine-Primed Reinstatement.

The context dependency of extinction negates the effectiveness of cognitive enhancement to reduce cocaine-primed reinstatement.

Behav Brain Res. 2013 Jun 21;
Hammond S, Wagner JJ

With respect to the treatment of addiction, the objective of extinction training is to… Continue reading

Pain Is Associated With Heroin Use Over Time in HIV-Infected Russian Drinkers.

Pain is Associated with Heroin Use over Time in HIV-Infected Russian Drinkers.

Addiction. 2013 Jun 17;
Tsui JI, Cheng DM, Coleman SM, Blokhina E, Bridden C, Krupitsky E, Samet JH

AIMS: To evaluate whether pain was associated with increased… Continue reading