clinical studies

Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson’s Disease With Neuroprotective Potential.

Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson’s Disease with Neuroprotective Potential.

Rambam Maimonides Med J. 2010 Jul; 1(1): e0003
Finberg JP

Rasagiline (Azilect) is a highly selective and potent propargylamine inhibitor of monoamine… Continue reading

Deep Brain Stimulation for the Treatment of Addiction: Basic and Clinical Studies and Potential Mechanisms of Action.

Deep brain stimulation for the treatment of addiction: basic and clinical studies and potential mechanisms of action.

Psychopharmacology (Berl). 2013 Aug 2;
Pierce RC, Vassoler FM

Deep brain stimulation (DBS) has achieved substantial success as a treatment for movement… Continue reading

Strategies to Increase Drug Penetration in Solid Tumors.

Strategies to increase drug penetration in solid tumors.

Front Oncol. 2013; 3: 193
Choi IK, Strauss R, Richter M, Yun CO, Lieber A

Despite significant improvement in modalities for treatment of cancer that led to a longer survival period,… Continue reading

Antiproliferative Activity of New Benzimidazole Derivatives.

Antiproliferative activity of new benzimidazole derivatives.

Acta Biochim Pol. 2013 Jul 25;
B?aszczak-?wi?tkiewicz K, Olszewska P, Mikiciuk-Olasik E

A series of new benzimidazole derivatives were synthesized and tested in vitro for possible anticancer activity. Their effect of proliferation into… Continue reading

Plurigon: Three Dimensional Visualization and Classification of High-Dimensionality Data.

Plurigon: three dimensional visualization and classification of high-dimensionality data.

Front Physiol. 2013; 4: 190
Martin B, Chen H, Daimon CM, Chadwick W, Siddiqui S, Maudsley S

High-dimensionality data is rapidly becoming the norm for biomedical sciences and many other… Continue reading

Implications of Genome Wide Association Studies for Addiction: Are Our a Priori Assumptions All Wrong?

Implications of genome wide association studies for addiction: Are our a priori assumptions all wrong?

Pharmacol Ther. 2013 Jul 18;
Hall FS, Drgonova J, Jain S, Uhl GR

Substantial genetic contributions to addiction vulnerability are supported by data from… Continue reading

The Role of Platelet-Rich Plasma in Inducing Musculoskeletal Tissue Healing.

The role of platelet-rich plasma in inducing musculoskeletal tissue healing.

HSS J. 2012 Jul; 8(2): 137-45
Halpern BC, Chaudhury S, Rodeo SA

Platelet-rich plasma [PRP] has received increasing interest across many musculoskeletal disciplines and has been widely applied clinically… Continue reading

Imaging Addiction: D2 Receptors and Dopamine Signaling in the Striatum as Biomarkers for Impulsivity.

Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity.

Neuropharmacology. 2013 Jul 9;
Trifilieff P, Martinez D

Dependence to drugs of abuse is closely associated with impulsivity, or the propensity to choose a lower,… Continue reading

Mutation in Ribosomal Protein S5 Leads to Spectinomycin Resistance in Neisseria Gonorrhoeae.

Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae.

Front Microbiol. 2013; 4: 186
Ilina EN, Malakhova MV, Bodoev IN, Oparina NY, Filimonova AV, Govorun VM

Spectinomycin remains a useful reserve option for therapy of gonorrhea.… Continue reading

Antidepressant Medication Use Among Patients With Depression: Comparison Between Usual Care and Collaborative Care Using Care Managers.

Antidepressant Medication Use Among Patients with Depression: Comparison between Usual Care and Collaborative Care Using Care Managers.

Clin Pract Epidemiol Ment Health. 2013; 9: 84-87
Dejesus RS, Angstman KB, Cha SS, Williams MD

Depression poses a significant economic and… Continue reading