Weak Affinity Chromatography for Evaluation of Stereoisomers in Early Drug Discovery.
Weak Affinity Chromatography for Evaluation of Stereoisomers in Early Drug Discovery.
J Biomol Screen. 2013 Mar 11;
Duong-Thi MD, Bergström M, Fex T, Svensson S, Ohlson S, Isaksson R
In early drug discovery (e.g., in fragment screening), recognition of… Continue reading
Efficient Generation of Stable Bispecific IgG1 by Controlled Fab-Arm Exchange.
Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.
Proc Natl Acad Sci U S A. 2013 Mar 11;
Labrijn AF, Meesters JI, de Goeij BE, van den Bremer ET, Neijssen J, van Kampen MD, Strumane K, Verploegen… Continue reading
Generation and Validation of a Zebrafish Model of EAST (Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy) Syndrome.
Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome.
Dis Model Mech. 2013 Feb 14;
Mahmood F, Mozere M, Zdebik AA, Stanescu HC, Tobin J, Beales PL, Kleta R, Bockenhauer D, Russell… Continue reading
The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/?-Catenin Signaling in Cancer Cells.
The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/?-Catenin Signaling in Cancer Cells.
PLoS One. 2013; 8(2): e58102
Lin C, Lu W, Zhang W, Londoño-Joshi AI, Buchsbaum DJ, Bu G, Li Y
While… Continue reading
[A New Method of Calibration and Positioning in Quantitative Analysis of Multicomponents by Single Marker].
[A new method of calibration and positioning in quantitative analysis of multicomponents by single marker].
Yao Xue Xue Bao. 2012 Dec; 47(12): 1653-9
He B, Yang SY, Zhang Y
This paper aims to establish a new method of calibration… Continue reading
The Μ Opioid Receptor and Ligands Acting at the Μ Opioid Receptor, as Therapeutics and Potential Therapeutics.
The µ Opioid Receptor and Ligands Acting at the µ Opioid Receptor, as Therapeutics and Potential Therapeutics.
Curr Pharm Des. 2013 Feb 20;
Spetea M, Asim MF, Wolber G, Schmidhammer H
Although the µ opioid receptor (MOR) was pharmacologically… Continue reading
Kinetic Modeling-Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.
Kinetic Modeling-Based Detection of Genetic Signatures that Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.
Cancer Res. 2013 Feb 27;
Vera J, Schmitz U, Lai X, Engelmann D, Khan FM, Wolkenhauer O, Putzer BM
Drug resistance is a major cause of… Continue reading
A More Balanced Approach to Drug-Grapefruit Juice Interactions.
A more balanced approach to drug-grapefruit juice interactions.
BMJ. 2013; 346: f1073
Backman WD, Bakhai A
Increased Glucagon-like peptide-1 secretion may be involved in anti-diabetic effects of ginsenosides.
J Endocrinol. 2013 Feb 26;
Liu… Continue reading
Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex.
Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex.
PLoS One. 2013; 8(2): e57445
Zhang B, McDaniel SS, Rensing NR, Wong M
Epilepsy is a common neurological disorder and cause of significant morbidity… Continue reading