cancer cells

Drug and Alcohol Rehabilitation: [Antibody-Drug Conjugates and Their Application in the Treatment of Hematological Malignancies].

[Antibody-drug conjugates and their application in the treatment of hematological malignancies].

Filed under: Drug and Alcohol Rehabilitation

Yao Xue Xue Bao. 2012 Oct; 47(10): 1287-96
Lin L, Ding Q, Tang Q, Zhang ZZ, Dai Z, Zhan JB

Monoclonal antibody-targeted… Continue reading

Layer-by-Layer Supramolecular Assemblies Based on Linear and Star-Shaped Poly(glycerol Methacrylate)s for Doxorubicin Delivery.

Layer-by-layer supramolecular assemblies based on linear and star-shaped poly(glycerol methacrylate)s for doxorubicin delivery.

Filed under: Drug and Alcohol Rehabilitation

J Biomed Mater Res A. 2012 Dec 22;
Sun Y, Gao H, Yang YW, Wang A, Wu G, Wang Y,… Continue reading

Drug and Alcohol Rehabilitation: Metformin Inhibits the Inflammatory Response Associated With Cellular Transformation and Cancer Stem Cell Growth.

Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth.

Filed under: Drug and Alcohol Rehabilitation

Proc Natl Acad Sci U S A. 2012 Dec 31;
Hirsch HA, Iliopoulos D, Struhl K

Metformin, the first-line… Continue reading

Drug and Alcohol Rehabilitation: Comparison of Aerobic Conjunctival Bacterial Flora in Pregnant, Reproductive-Aged and Postmenopausal Women.

Comparison of aerobic conjunctival bacterial flora in pregnant, reproductive-aged and postmenopausal women.

Filed under: Drug and Alcohol Rehabilitation

Int J Ophthalmol. 2012; 5(6): 731-6
Balikoglu-Yilmaz M, Sen E, Sevket O, Polat Y, Karabulut A, Uysal O

To evaluate the effect of hormonal status on aerobic conjunctival flora in women.One hundred fifty-eight women [reproductive-aged (n=55), pregnant (n=51), and postmenopausal (n=52)] who admitted to outpatient clinic of Obstetrics and Gynecology Department of Denizli State Hospital were enrolled. Age, body-mass index (BMI), obstetric history, cigarette smoking, drug usage, presence of systemic disease, and intraocular pressure (IOP) were recorded for each patient. The samples were taken from the lower fornix with two culture swabs and directly incubated in culture containing 5% sheep blood, eosin-methylene blue and chocolate agar. The other swab specimen was Gram stained. All growths and microscopic results were analyzed.The coagulase-negative Staphylococcus was the predominant organism isolated in the conjunctival samples in both three groups. The aerobic microorganism growth rate for all isolated aerobic organisms revealed no significant change in the three groups (P >0.05). The conjunctival culture positivity rates were similar in the three groups (49% in reproductive-aged, 57% in pregnant and 58% in postmenopausal women) (P >0.05). Age, IOP,… Continue reading

Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model With Decreased Sensitivity to Histone Deacetylase Inhibition.

Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model with Decreased Sensitivity to Histone Deacetylase Inhibition.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2012; 7(12): e52335
Smith SJ, Wilson M, Ward JH, Rahman CV,… Continue reading

Recurring Extracorporeal Circuit Clotting During Continuous Renal Replacement Therapy in a Patient With Scedosporium Prolificans-Induced Fungal Sepsis: Successful Treatment With Argatroban.

Recurring Extracorporeal Circuit Clotting During Continuous Renal Replacement Therapy in a Patient With Scedosporium prolificans-Induced Fungal Sepsis: Successful Treatment With Argatroban.

Filed under: Drug and Alcohol Rehabilitation

Am J Med Sci. 2012 Dec 21;
Ferguson LM, Dreisbach AW, Csongrádi… Continue reading

ABCC4/MRP4: A MYCN-Regulated Transporter and Potential Therapeutic Target in Neuroblastoma.

ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma.

Filed under: Drug and Alcohol Rehabilitation

Front Oncol. 2012; 2: 178
Huynh T, Norris MD, Haber M, Henderson MJ

Resistance to cytotoxic drugs is thought to be a major… Continue reading

Drug and Alcohol Rehabilitation: New Stability-Indicating RP-UFLC Method for Determination of Trospium Chloride in Tablet Dosage Form.

New Stability-Indicating RP-UFLC Method for Determination of Trospium Chloride in Tablet Dosage Form.

Filed under: Drug and Alcohol Rehabilitation

Sci Pharm. 2012 Dec; 80(4): 955-64
Panda SS, Ravi Kumar BV, Mohanta G, Dash R, Patel PK

A simple, precise,… Continue reading

Addiction Rehab: Regulation of BDNF Expression by Cocaine.

Regulation of BDNF expression by cocaine.

Filed under: Addiction Rehab

Yale J Biol Med. 2012 Dec; 85(4): 437-46
McCarthy DM, Brown AN, Bhide PG

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors. It… Continue reading

Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal, SH-SY5Y Cells.

Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal, SH-SY5Y Cells.

Filed under: Addiction Rehab

PLoS One. 2012; 7(12): e51111
Narasimhan M, Patel D, Vedpathak D, Rathinam M, Henderson G, Mahimainathan L

Nuclear… Continue reading