Wang J

Structural Evidence for a Bifurcated Mode of Action in the Antibody-Mediated Neutralization of Hepatitis C Virus.

Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus.

Proc Natl Acad Sci U S A. 2013 Apr 15;
Deng L, Zhong L, Struble E, Duan H, Ma L, Harman C, Yan… Continue reading

Does the Knowledge-to-Action (KTA) Framework Facilitate Physical Demands Analysis Development for Firefighter Injury Management and Return-to-Work Planning?

Does the Knowledge-to-Action (KTA) Framework Facilitate Physical Demands Analysis Development for Firefighter Injury Management and Return-to-Work Planning?

J Occup Rehabil. 2013 Apr 13;
Sinden K, Macdermid JC

Purpose Employers are tasked with developing injury management and return-to-work (RTW) programs… Continue reading

Development of a Preclinical PK/PD Model to Assess Antitumor Response of a Sequential Aflibercept and Doxorubicin-Dosing Strategy in Acute Myeloid Leukemia.

Development of a Preclinical PK/PD Model to Assess Antitumor Response of a Sequential Aflibercept and Doxorubicin-Dosing Strategy in Acute Myeloid Leukemia.

AAPS J. 2013 Apr 3;
Fetterly GJ, Aras U, Lal D, Murphy M, Meholick PD, Wang ES

Timing… Continue reading

Transcriptome Sequencing of Gene Expression in the Brain of the HIV-1 Transgenic Rat.

Transcriptome Sequencing of Gene Expression in the Brain of the HIV-1 Transgenic Rat.

PLoS One. 2013; 8(3): e59582
Li MD, Cao J, Wang S, Wang J, Sarkar S, Vigorito M, Ma JZ, Chang SL

The noninfectious HIV-1 transgenic (HIV-1Tg)… Continue reading

Intake of Game Birds in the UK: Assessment of the Contribution to the Dietary Intake of Lead by Women of Childbearing Age and Children.

Intake of game birds in the UK: assessment of the contribution to the dietary intake of lead by women of childbearing age and children.

Public Health Nutr. 2013 Mar 26; 1-5
Taylor CM, Golding J, Emond AM

OBJECTIVE: Concern has recently been expressed about Pb levels in Pb-shot game meat. Our aim was to determine the consumption of game birds in a representative sample population in the UK, and in children and women of childbearing age in particular. DESIGN: Population-based cross-sectional cohort study. Data from 4 d diet diaries from the UK National Diet and Nutrition Survey (NDNS; 2008-2010) were extracted to analyse data on game bird consumption in the sample population, in women of childbearing age (15-45 years old) and in children ?6 years old. SETTING: Home-based study in representative areas of the UK. SUBJECTS: Participants in the NDNS (2008-2010; n 2126, age 1·5 to >65 years).… Continue reading

Induction of Thoracic Aortic Remodeling by Endothelial-Specific Deletion of MicroRNA-21 in Mice.

Induction of Thoracic Aortic Remodeling by Endothelial-Specific Deletion of MicroRNA-21 in Mice.

PLoS One. 2013; 8(3): e59002
Zhang XY, Shen BR, Zhang YC, Wan XJ, Yao QP, Wu GL, Wang JY, Chen SG, Yan ZQ, Jiang ZL

MicroRNAs (miRs)… Continue reading

Does Pharmacogenomics Account for Variability in Control of Acute Chemotherapy-Induced Nausea and Vomiting With 5-Hydroxytryptamine Type 3 Receptor Antagonists?

Does Pharmacogenomics Account for Variability in Control of Acute Chemotherapy-Induced Nausea and Vomiting with 5-Hydroxytryptamine Type 3 Receptor Antagonists?

Curr Oncol Rep. 2013 Mar 21;
Trammel M, Roederer M, Patel J, McLeod H

Chemotherapy-induced nausea and vomiting is one… Continue reading

3.0-T MR Imaging of Intracoronary Local Delivery of Motexafin Gadolinium Into Coronary Artery Walls.

3.0-T MR Imaging of Intracoronary Local Delivery of Motexafin Gadolinium into Coronary Artery Walls.

Radiology. 2013 Mar 19;
Meng Y, Wang J, Sun J, Zhang F, Willis P, Li J, Wang H, Zhang T, Soriano S, Qiu B, Yang… Continue reading

Genetic Variants of Uncoupling Proteins-2 and -3 in Relation to Maximal Oxygen Uptake in Different Sports.

Genetic variants of uncoupling proteins-2 and -3 in relation to maximal oxygen uptake in different sports.

Acta Biochim Pol. 2013 Mar 15;
Holdys J, Gronek P, Kry?ciak J, Stanis?awski D

Uncoupling proteins 2 and 3 (UCP2 and UCP3) as mitochondrial electron transporters are involved in regulation of ATP production and energy dissipation as heat. Energy efficiency plays an important role in physical performance, especially in aerobic fitness. The aim of this study was to examine the association between maximal oxygen uptake and genetic variants of the UCP2 and UCP3 genes. The studies were carried out in a group of 154 men and 85 women, professional athletes representing various sports and fitness levels and students of the University of Physical Education in Pozna?. Physiological and molecular procedures were used, i.e. direct measurement of maximum oxygen uptake (VO2max) and analysis of an insertion/deletion (I/D) polymorphism in the 3’untranslated region of exon 8 of the UCP2 gene and a C\>T substitution in exon 5 (Y210Y) of the UCP3… Continue reading

Changes in Corticospinal Excitability Following Adaptive Modification to Human Walking.

Changes in corticospinal excitability following adaptive modification to human walking.

Exp Brain Res. 2013 Mar 15;
Zabukovec JR, Boyd LA, Linsdell MA, Lam T

Locomotor adaptations to a novel environment can be measured through changes in muscle activity patterns… Continue reading