Lipids and Addiction: How Sex Steroids, Prostaglandins, and Cannabinoids Interact With Drugs of Abuse.
Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse.
Ann N Y Acad Sci. 2013 Mar 19;
Leishman E, Kokesh KJ, Bradshaw HB
Lipidomics aims to identify and characterize all endogenous species of lipids… Continue reading
Dantrolene-Induced Inhibition of Skeletal L-Type Ca(2+) Current Requires RyR1 Expression.
Dantrolene-Induced Inhibition of Skeletal L-Type Ca(2+) Current Requires RyR1 Expression.
Biomed Res Int. 2013; 2013: 390493
Bannister RA
Malignant hyperthermia (MH) is a pharmacogenetic disorder most often linked to mutations in the type 1 ryanodine receptor (RyR1) or the… Continue reading
Addressing Missing Data Mechanism Uncertainty Using Multiple-Model Multiple Imputation: Application to a Longitudinal Clinical Trial.
Addressing Missing Data Mechanism Uncertainty using Multiple-Model Multiple Imputation: Application to a Longitudinal Clinical Trial.
Ann Appl Stat. 2012 Dec 1; 6(4): 1814-1837
Siddique J, Harel O, Crespi CM
We present a framework for generating multiple imputations for continuous… Continue reading
Intermittent Access to Sweet High-Fat Liquid Induces Increased Palatability and Motivation to Consume in a Rat Model of Binge Consumption.
Intermittent access to sweet high-fat liquid induces increased palatability and motivation to consume in a rat model of binge consumption.
Physiol Behav. 2013 Mar 13;
Lardeux S, Kim JJ, Nicola SM
Binge eating disorders are characterized by discrete episodes… Continue reading
A Medical Oncologist’s Perspective on Communication Skills and Burnout Syndrome With Psycho-Oncological Approach (To Die With Each Patient One More Time: The Fate of the Oncologists).
A medical oncologist’s perspective on communication skills and burnout syndrome with psycho-oncological approach (To die with each patient one more time: the fate of the oncologists).
Med Oncol. 2013 Jun; 30(2): 530
Tanriverdi O
The increasing incidence of cancer… Continue reading
Comparative Performance of Two Drug Interaction Screening Programmes Analysing a Cross-Sectional Prescription Dataset of 84,625 Psychiatric Inpatients.
Comparative Performance of Two Drug Interaction Screening Programmes Analysing a Cross-Sectional Prescription Dataset of 84,625 Psychiatric Inpatients.
Drug Saf. 2013 Mar 14;
Zorina OI, Haueis P, Greil W, Grohmann R, Kullak-Ublick GA, Russmann S
BACKGROUND: Clinical decision support software… Continue reading
A Prospective Study of Neurocognitive Changes 15 Years After Chronic Inhalant Abuse.
A prospective study of neurocognitive changes 15 years after chronic inhalant abuse.
Addiction. 2013 Mar 13;
Cairney S, O’ Connor N, Dingwall KM, Maruff P, Shafiq-Antonacci R, Currie J, Currie BJ
AIMS: In a previous study, neurological and cognitive deficits reflecting central nervous system (CNS) disruption from chronic inhalant abuse showed substantial recovery after 2 years’ abstinence. Functional recovery was progressive, with recovery rates dependent on the degree of impairment prior to abstinence, and severity and duration of initial abuse. Persistent deficits occurred in those with previous ‘lead encephalopathy’ from leaded petrol abuse. The current study examined recovery in the same cohort 15 years after baseline. DESIGN: Prospective cohort design. SETTING: Two remote Aboriginal communities in Arnhem Land, Australia. PARTICIPANTS: Using baseline group classifications, 27 healthy controls, 60 ex-chronic inhalant abusers and an additional 17 with previous lead encephalopathy were assessed. MEASUREMENTS: Standard neurological, ocular-motor and cognitive functions and blood lead levels. FINDINGS: Chronic (non-encephalopathic) inhalant abusers showed elevated blood lead levels and abnormal scores on most tasks at baseline. At 2 years’ abstinence, blood lead was reduced but remained elevated and most scores had normalized. By 15 years, blood lead and all performance scores were equivalent to healthy controls for this group (P?>?0.05). The encephalopathic group was more severely impaired… Continue reading
Episodes of Breathlessness: Types and Patterns – a Qualitative Study Exploring Experiences of Patients With Advanced Diseases.
Episodes of breathlessness: Types and patterns – a qualitative study exploring experiences of patients with advanced diseases.
Palliat Med. 2013 Mar 13;
Simon ST, Higginson IJ, Benalia H, Gysels M, Murtagh FE, Spicer J, Bausewein C
Background:Despite the high… Continue reading