THE CLINIC

QSAR Models for the Prediction of Plasma Protein Binding.

QSAR models for the prediction of plasma protein binding.

Bioimpacts. 2013; 3(1): 21-7
Ghafourian T, Amin Z

The prediction of plasma protein binding (ppb) is of paramount importance in the pharmacokinetics characterization of drugs, as it causes significant changes… Continue reading

Will Sociology or Psychology Help Me More in the Career I Want to Pursue?

Question by Amber: Will sociology or psychology help me more in the career I want to pursue?
I want to either work in a mental hospital or an eating disorder clinic. Just some sore of ward or clinic of some… Continue reading

Tumor Burden Talks in Cancer Treatment With PEGylated Liposomal Drugs.

Tumor Burden Talks in Cancer Treatment with PEGylated Liposomal Drugs.

PLoS One. 2013; 8(5): e63078
Lin YY, Kao HW, Li JJ, Hwang JJ, Tseng YL, Lin WJ, Lin MH, Ting G, Wang HE

PEGylated liposomes are important drug carriers that can passively target tumor by enhanced permeability and retention (EPR) effect in neoplasm lesions. This study demonstrated that tumor burden determines the tumor uptake, and also the tumor response, in cancer treatment with PEGylated liposomal drugs in a C26/tk-luc colon carcinoma-bearing mouse model.Empty PEGylated liposomes (NanoX) and those encapsulated with VNB (NanoVNB) were labeled with In-111 to obtain InNanoX and InVNBL in high labeling yield and radiochemical purity (all >90%). BALB/c mice bearing either small… Continue reading

Corticosterone Facilitates Fluoxetine-Induced Neuronal Plasticity in the Hippocampus.

Corticosterone Facilitates Fluoxetine-Induced Neuronal Plasticity in the Hippocampus.

PLoS One. 2013; 8(5): e63662
Kobayashi K, Ikeda Y, Asada M, Inagaki H, Kawada T, Suzuki H

The hippocampal dentate gyrus has been implicated in a neuronal basis of antidepressant action.… Continue reading

How Does Antiretroviral Treatment Attenuate the Stigma of HIV? Evidence From a Cohort Study in Rural Uganda.

How Does Antiretroviral Treatment Attenuate the Stigma of HIV? Evidence from a Cohort Study in Rural Uganda.

AIDS Behav. 2013 May 14;
Tsai AC, Bangsberg DR, Bwana M, Haberer JE, Frongillo EA, Muzoora C, Kumbakumba E, Hunt PW, Martin… Continue reading

Insight in Alzheimer’s Disease and Its Relation to Psychiatric and Behavioral Disturbances.

Insight in Alzheimer’s disease and its relation to psychiatric and behavioral disturbances.

Int J Geriatr Psychiatry. 2013 May 14;
Horning SM, Melrose R, Sultzer D

OBJECTIVE: Individuals suffering from Alzheimer’s disease (AD) often have impaired awareness or a lack… Continue reading

Protective Effects of Resveratrol on TNF-?-Induced Endothelial Cytotoxicity in Baboon Femoral Arterial Endothelial Cells.

Protective Effects of Resveratrol on TNF-?-Induced Endothelial Cytotoxicity in Baboon Femoral Arterial Endothelial Cells.

J Diabetes Res. 2013; 2013: 185172
Xiao J, Song J, Hodara V, Ford A, Wang XL, Shi Q, Chen L, Vandeberg JL

Endothelial injury induced… Continue reading

A Cross-Cultural Validation of the Clinician Administered PTSD Scale for Children and Adolescents in a Dutch Population.

A cross-cultural validation of the Clinician Administered PTSD Scale for Children and Adolescents in a Dutch population.

Eur J Psychotraumatol. 2013; 4:
Diehle J, de Roos C, Boer F, Lindauer RJ

Trauma-focused interventions for children could be administered more… Continue reading

Efficacy and Safety of Short-Term Use of COX-2 Inhibitors in Patients After an Acute Stroke With Musculoskeletal Pain.

Efficacy and safety of short-term use of COX-2 inhibitors in patients after an acute stroke with musculoskeletal pain.

Ann Indian Acad Neurol. 2013 Jan; 16(1): 47-52
Rabadi MH, Rabadi FM, Hallford G, Aston CE

Musculoskeletal pain commonly occurs in… Continue reading

An Evolutionary Perspective on Food and Human Taste.

An evolutionary perspective on food and human taste.

Curr Biol. 2013 May 6; 23(9): R409-18
Breslin PA

The sense of taste is stimulated when nutrients or other chemical compounds activate specialized receptor cells within the oral cavity. Taste helps… Continue reading