synaptic plasticity

A? Induces Astrocytic Glutamate Release, Extrasynaptic NMDA Receptor Activation, and Synaptic Loss.

A? induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.

Proc Natl Acad Sci U S A. 2013 Jun 17;
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto SI, Dziewczapolski G, Nakamura T, Cao… Continue reading

Characterizing Protein Domain Associations by Small-Molecule Ligand Binding.

Characterizing protein domain associations by Small-molecule ligand binding.

J Proteome Sci Comput Biol. 2012 Dec 3; 1:
Li Q, Cheng T, Wang Y, Bryant SH

Protein domains are evolutionarily conserved building blocks for protein structure and function, which are… Continue reading

Breaking Worse: The Emergence of Krokodil and Excessive Injuries Among People Who Inject Drugs in Eurasia.

Breaking worse: The emergence of krokodil and excessive injuries among people who inject drugs in Eurasia.

Int J Drug Policy. 2013 May 30;
Grund JP, Latypov A, Harris M

BACKGROUND: Krokodil, a homemade injectable opioid, gained its moniker from… Continue reading

Caudal Epidural Blockade in Adolescents.

Caudal epidural blockade in adolescents.

Saudi J Anaesth. 2013 Jan; 7(1): 57-60
Schloss B, Jayanthi VR, Bhalla T, Tobias JD

Various options are available for the provision of analgesia following major surgical procedures including systemic opioids and regional anesthetic… Continue reading

The Role of Extracellular Proteolysis in Synaptic Plasticity of the Central Nervous System .

The role of extracellular proteolysis in synaptic plasticity of the central nervous system .

Postepy Hig Med Dosw (Online). 2012; 66: 959-75
Ziemia?ska K, Konopka A, Wilczy?ski GM

The extracellular matrix (ECM) of the central nervous system has… Continue reading

Rapid Feedback Regulation of Synaptic Efficacy During High-Frequency Activity at the Drosophila Larval Neuromuscular Junction.

Rapid feedback regulation of synaptic efficacy during high-frequency activity at the Drosophila larval neuromuscular junction.

Proc Natl Acad Sci U S A. 2013 May 14;
Kauwe G, Isacoff EY

High-frequency firing of neurons depresses transmitter release at many synapses.… Continue reading

Pearls and Pitfalls in Experimental Models of Spreading Depression.

Pearls and pitfalls in experimental models of spreading depression.

Cephalalgia. 2013 Jun; 33(8): 604-13
Ayata C

Spreading depression (SD) is the electrophysiological substrate of migraine aura and a potential trigger for headache. Since its discovery by Leão in 1944,… Continue reading

Amphetamine Elicits Opposing Actions on Readily Releasable and Reserve Pools for Dopamine.

Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine.

PLoS One. 2013; 8(5): e60763
Covey DP, Juliano SA, Garris PA

Amphetamine, a highly addictive drug with therapeutic efficacy, exerts paradoxical effects on the fundamental communication modes… Continue reading

Rapid, Transient Potentiation of Dendritic Spines in Context-Induced Relapse to Cocaine Seeking.

Rapid, transient potentiation of dendritic spines in context-induced relapse to cocaine seeking.

Addict Biol. 2013 May 6;
Stankeviciute NM, Scofield MD, Kalivas PW, Gipson CD

Addiction to cocaine produces long-lasting, stable changes in brain synaptic physiology that might contribute… Continue reading

The Role of Galanin System in Modulating Depression, Anxiety, and Addiction-Like Behaviors After Chronic Restraint Stress.

The role of galanin system in modulating depression, anxiety, and addiction-like behaviors after chronic restraint stress.

Neuroscience. 2013 Apr 29;
Zhao X, Seese RR, Yun K, Peng T, Wang Z

There is high comorbidity between stress-related psychiatric disorders and… Continue reading