Signal transduction

The Role of the Aversive Effects of Drugs in Self-Administration: Assessing the Balance of Reward and Aversion in Drug-Taking Behavior.

The role of the aversive effects of drugs in self-administration: assessing the balance of reward and aversion in drug-taking behavior.

Behav Pharmacol. 2013 Jul 16;
Verendeev A, Riley AL

Since the first experimental demonstration that a drug of abuse… Continue reading

Overview of Cancer Stem Cells (CSCs) and Mechanisms of Their Regulation: Implications for Cancer Therapy.

Overview of Cancer Stem Cells (CSCs) and Mechanisms of Their Regulation: Implications for Cancer Therapy.

Curr Protoc Pharmacol. 2013 Jun; Chapter 14: Unit14.25
Bao B, Ahmad A, Azmi AS, Ali S, Sarkar FH

The identification of small subpopulations of… Continue reading

Targeting Nuclear Factor-Kappa B to Overcome Resistance to Chemotherapy.

Targeting Nuclear Factor-Kappa B to Overcome Resistance to Chemotherapy.

Front Oncol. 2013; 3: 120
Godwin P, Baird AM, Heavey S, Barr MP, O’Byrne KJ, Gately K

Intrinsic or acquired resistance to chemotherapeutic agents is a common phenomenon and a… Continue reading

Comparison of Responses of Human Melanoma Cell Lines to MEK and BRAF Inhibitors.

Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.

Front Genet. 2013; 4: 66
Stones CJ, Kim JE, Joseph WR, Leung E, Marshall ES, Finlay GJ, Shelling AN, Baguley BC

The NRAS and BRAF genes… Continue reading

PET Radiopharmaceuticals for Probing Enzymes in the Brain.

PET radiopharmaceuticals for probing enzymes in the brain.

Am J Nucl Med Mol Imaging. 2013; 3(3): 194-216
Holland JP, Cumming P, Vasdev N

Biologically important processes in normal brain function and brain disease involve the action of various protein-based… Continue reading

Treatment-Enhanced Paired Action Contributes Substantially to Change Across Multiple Health Behaviors: Secondary Analyses of Five Randomized Trials.

Treatment-enhanced paired action contributes substantially to change across multiple health behaviors: secondary analyses of five randomized trials.

Transl Behav Med. 2013 Mar 1; 3(1): 62-71
Yin HQ, Prochaska JO, Rossi JS, Redding CA, Paiva AL, Blissmer B, Velicer WF,… Continue reading

Nicotine and Lung Cancer.

Nicotine and lung cancer.

J Carcinog. 2013; 12: 1
Warren GW, Singh AK

Tobacco use in cancer patients is associated with increased cancer treatment failure and decreased survival. Nicotine is one of over 7,000 compounds in tobacco smoke and… Continue reading

“Exercise Is Medicine”: Curbing the Burden of Chronic Disease and Physical Inactivity.

“Exercise Is Medicine”: Curbing the Burden of Chronic Disease and Physical Inactivity.

Asia Pac J Public Health. 2013 Apr 9;
Coombes JS, Law J, Lancashire B, Fassett RG

An exercise program designed to improve fitness is essential for most… Continue reading

NCK2 Is Significantly Associated With Opiates Addiction in African-Origin Men.

NCK2 Is Significantly Associated with Opiates Addiction in African-Origin Men.

ScientificWorldJournal. 2013; 2013: 748979
Liu Z, Guo X, Jiang Y, Zhang H

Substance dependence is a complex environmental and genetic disorder with significant social and medical concerns. Understanding the… Continue reading

Antipurinergic Therapy Corrects the Autism-Like Features in the Poly(IC) Mouse Model.

Antipurinergic Therapy Corrects the Autism-Like Features in the Poly(IC) Mouse Model.

PLoS One. 2013; 8(3): e57380
Naviaux RK, Zolkipli Z, Wang L, Nakayama T, Naviaux JC, Le TP, Schuchbauer MA, Rogac M, Tang Q, Dugan LL, Powell SB

Autism… Continue reading