receptor antagonist

Optimization of Drug Delivery Systems for Intraperitoneal Therapy to Extend the Residence Time of the Chemotherapeutic Agent.

Optimization of drug delivery systems for intraperitoneal therapy to extend the residence time of the chemotherapeutic agent.

ScientificWorldJournal. 2013; 2013: 720858
De Smet L, Ceelen W, Remon JP, Vervaet C

Intraperitoneal (IP) chemotherapy is an effective way of treating… Continue reading

Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor.

Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor.

PLoS One. 2013; 8(4): e59778
Sakaki H, Tsukimoto M, Harada H, Moriyama Y, Kojima S

It is important to understand the mechanisms that regulate macrophage… Continue reading

Microinjection of Ghrelin in the Nucleus Accumbens Core Enhances Locomotor Activity Induced by Cocaine.

Microinjection of ghrelin in the nucleus accumbens core enhances locomotor activity induced by cocaine.

Behav Brain Res. 2013 Apr 8;
Jang JK, Kim WY, Cho BR, Lee JW, Kim JH

Ghrelin has a regulatory role not only in the… Continue reading

GET73 Increases Rat Extracellular Hippocampal CA1 GABA Levels Through a Possible Involvement of Local mGlu5 Receptor.

GET73 increases rat extracellular hippocampal CA1 GABA levels through a possible involvement of local mGlu5 receptor.

Synapse. 2013 Apr 8;
Beggiato S, O’Connor WT, Tomasini MC, Antonelli T, Loche A, Tanganelli S, Cacciaglia R, Ferraro L

N-[(4-trifluoromethyl) benzyl] 4-methoxybutyramide… Continue reading

Clinical Spectrum and Therapeutic Approach to Hepatocellular Injury in Patients With Hyperthyroidism.

Clinical spectrum and therapeutic approach to hepatocellular injury in patients with hyperthyroidism.

Clin Exp Gastroenterol. 2013; 6: 9-17
de Campos Mazo DF, de Vasconcelos GB, Pereira MA, de Mello ES, Bacchella T, Carrilho FJ, Cançado EL

Liver dysfunction in… Continue reading

Response to Letter Regarding Article, “Short- and Long-Term Outcomes With Drug-Eluting and Bare-Metal Coronary Stents: A Mixed-Treatment Comparison Analysis of 117,762 Patient-Years of Follow-Up From Randomized Trials”.

Response to letter regarding article, “Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison Analysis of 117,762 patient-years of follow-up from randomized trials”.

Circulation. 2013 Feb 12; 127(6): e447
Bangalore S, Fusaro M, Amoroso N,… Continue reading

Does Pharmacogenomics Account for Variability in Control of Acute Chemotherapy-Induced Nausea and Vomiting With 5-Hydroxytryptamine Type 3 Receptor Antagonists?

Does Pharmacogenomics Account for Variability in Control of Acute Chemotherapy-Induced Nausea and Vomiting with 5-Hydroxytryptamine Type 3 Receptor Antagonists?

Curr Oncol Rep. 2013 Mar 21;
Trammel M, Roederer M, Patel J, McLeod H

Chemotherapy-induced nausea and vomiting is one… Continue reading

Detection of Epigenetic Changes Using ANOVA With Spatially Varying Coefficients.

Detection of epigenetic changes using ANOVA with spatially varying coefficients.

Stat Appl Genet Mol Biol. 2013 Mar 13; 1-17
Guanghua X, Xinlei W, Quincey L, Nestler EJ, Xie Y

Abstract Identification of genome-wide epigenetic changes, the stable changes in… Continue reading

Train-of-Four and Tetanic Fade Are Not Always a Prejunctional Phenomenon as Evaluated by Toxins Having Highly Specific Pre- and Postjunctional Actions.

Train-of-Four and Tetanic Fade Are Not Always a Prejunctional Phenomenon as Evaluated by Toxins Having Highly Specific Pre- and Postjunctional Actions.

Anesth Analg. 2013 Mar 11;
Nagashima M, Yasuhara S, Martyn JA

BACKGROUND:Nerve-stimulated fade in muscle is generally accepted… Continue reading

Melatonin and Its Agonists in Pain Modulation and Its Clinical Application.

Melatonin and its agonists in pain modulation and its clinical application.

Arch Ital Biol. 2012 Dec; 150(4): 274-92
Srinivasan V, Zakaria R, Jeet Singh H, Acuna-Castroviejo D

Melatonin, the hormone of darkness has many physiological functions in the body… Continue reading