potassium channel

Inhibition of Kv4.3 Potassium Channels by Trazodone.

Inhibition of Kv4.3 potassium channels by trazodone.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Apr 25;
Chae YJ, Choi JS, Hahn SJ

Trazodone, a triazolopyridine antidepressant, is commonly used in the treatment of depression and insomnia. Kv4.3 channels are transiently, and… Continue reading

The KCNH2 Genetic Polymorphism (1956, C>T) Is a Novel Biomarker That Is Associated With CCB and ?,?-ADR Blocker Response in EH Patients in China.

The KCNH2 Genetic Polymorphism (1956, C>T) Is a Novel Biomarker That Is Associated with CCB and ?,?-ADR Blocker Response in EH Patients in China.

PLoS One. 2013; 8(4): e61317
He F, Luo J, Luo Z, Fan L, He Y, Zhu D, Gao J, Deng… Continue reading

Antibiotic Resistance and Carriage Class 1 and 2 Integrons in Clinical Isolates of Acinetobacter Baumannii From Tehran, Iran.

Antibiotic resistance and carriage class 1 and 2 integrons in clinical isolates of Acinetobacter baumannii from Tehran, Iran.

Asian Pac J Trop Biomed. 2013 Feb; 3(2): 140-145
Mirnejad R, Mostofi S, Masjedian F, Fooladi AA

To investigate antibiotic resistance… Continue reading

Agomelatine: A Review of Adverse Effects.

Agomelatine: a review of adverse effects.

Prescrire Int. 2013 Mar; 22(136): 70-1

More pharmacovigilance data on agomelatine became available in 2012. The main sources of information were surveillance data from the French national monitoring system, EU periodic safety update… Continue reading

[Non-Motor Symptoms in Myasthenia Gravis: Attributed to T-Cell Clones From Thymoma].

[Non-motor Symptoms in Myasthenia Gravis: Attributed to T-cell Clones from Thymoma].

Brain Nerve. 2013 Apr; 65(4): 477-83
Suzuki S

Abstract Autoimmune myasthenia gravis (MG) comprises a broad spectrum of non-motor symptoms. Patients with MG sometimes have psychiatric symptoms, such… Continue reading

Generation and Validation of a Zebrafish Model of EAST (Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy) Syndrome.

Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome.

Dis Model Mech. 2013 Feb 14;
Mahmood F, Mozere M, Zdebik AA, Stanescu HC, Tobin J, Beales PL, Kleta R, Bockenhauer D, Russell… Continue reading

Rehab Centers: Opening of Astrocytic Mitochondrial ATP-Sensitive Potassium Channels Upregulates Electrical Coupling Between Hippocampal Astrocytes in Rat Brain Slices.

Opening of Astrocytic Mitochondrial ATP-Sensitive Potassium Channels Upregulates Electrical Coupling between Hippocampal Astrocytes in Rat Brain Slices.

Filed under: Rehab Centers

PLoS One. 2013; 8(2): e56605
Wang J, Li Z, Feng M, Ren K, Shen G, Zhao C, Jin… Continue reading

Drug and Alcohol Rehabilitation: A Mathematical Model for Thermosensitive Liposomal Delivery of Doxorubicin to Solid Tumour.

A mathematical model for thermosensitive liposomal delivery of Doxorubicin to solid tumour.

Filed under: Drug and Alcohol Rehabilitation

J Drug Deliv. 2013; 2013: 172529
Zhan W, Xu XY

The effectiveness of anticancer treatments is often hampered by the serious… Continue reading

[Zebrafish as a Model Animal for the Study of Blood-Brain Barrier Permeability by Biomolecules].

[Zebrafish as a model animal for the study of blood-brain barrier permeability by biomolecules].

Filed under: Drug and Alcohol Rehabilitation

Yao Xue Xue Bao. 2012 Nov; 47(11): 1447-51
Fu AL, Chen HY, Xu XR, Zhao BQ

Blood-brain barrier (BBB)… Continue reading

Depression Treatment: A Novel Metabotropic Glutamate Receptor 5 Positive Allosteric Modulator Acts at a Unique Site and Confers Stimulus Bias to mGlu5 Signaling.

A Novel Metabotropic Glutamate Receptor 5 Positive Allosteric Modulator Acts at a Unique Site and Confers Stimulus Bias to mGlu5 Signaling.

Filed under: Depression Treatment

Mol Pharmacol. 2013 Jan 24;
Noetzel MJ, Gregory KJ, Vinson PN, Manka JT, Stauffer… Continue reading